Acid Mordant Orange 14 Property

Melting point:

244°C (rough estimate)

Boiling point:

427.65°C (rough estimate)

Density 

1.3989 (rough estimate)

refractive index 

1.4700 (estimate)

storage temp. 

-20°C Freezer, Under inert atmosphere

solubility 

Dichloromethane (Slightly), DMSO (Slightly)

form 

Solid

pka

3.95±0.20(Predicted)

color 

Dark Yellow to Very Dark Yellow

NIST Chemistry Reference

3-Nitroalizarine(568-93-4)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Acid Mordant Orange 14 Chemical Properties,Usage,Production

Uses

1,2-Dihydroxy-3-nitroanthraquinone (cas# 568-93-4) is useful for the development of allosteric PGAM1 inhibitors that are effective at suppressing the proliferation of pancreatic ductal adenocarcinoma cells.

Uses

Dyes cloth mordanted with Al orange, with Fe red to violet. As indicator in satd alcohol solution. pH 2.0-4.0, color change from golden orange to flat yellow (in water). pH 5.0-6.5 from yellow to purplish red.

Preparation

(a) in the presence of boric acid 1,2-Dihydroxyanthracene-9,10-dione?in sulfuric acid in the nitration; (b) 1,2-Dihydroxyanthracene-9,10-dione?in glacial acetic acid, toluene, petroleum ether or the nitration of nitrobenzene.

Properties and Applications

red light brown (chromium), red orange (aluminum). Insoluble in water. In concentrated sulfuric acid to orange, dilution after yellow.

Purification Methods

Crystallise the dye from AcOH (m 244-245o). It has max at 494nm (H2SO4) and forms Cu salts. [Beilstein 8 H 447, 8 II 491, 8 III 3774, 8 IV 2359.]