thiocolchicine

Product Name: thiocolchicine
CAS No.: 2730-71-4
Chemical Name: thiocolchicine
Synonyms: NSC 186301;thiocolchicine;thiocholchicine;10-Thiocolchicine;Thiocolchicine, 10 mM in DMSO;Thiocolchicoside EP Impurity B;10-Demethoxy-10-methylthiocolchicine;(S)-7-Acetylamino-6,7-dihydro-10-methylthio-1,2,3-trimethoxybenzo[a]heptalen-9(5H)-one;(S)-7α-Acetylamino-6,7-dihydro-10-(methylthio)-1,2,3-trimethoxybenzo[a]heptalene-9(5H)-one;N-[(S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-methylthio-9-oxobenzo[a]heptalen-7-yl]acetamide
CBNumber: CB1926071
Molecular Formula: C22H25NO5S
Formula Weight: 415.5
MOL File: 2730-71-4.mol

More

Less

thiocolchicine Property

Melting point:: 193℃
alpha: D20 -221°
Boiling point:: 729.1±60.0 °C(Predicted)
Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO: soluble10mg/mL, clear
pka: 14.75±0.40(Predicted)
form: powder
color: white to beige

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
RIDADR: UN 1544PSN1 6.1 / PGI
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H318Causes serious eye damage

H340May cause genetic defects

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0954
Product name: Thiocolchicine
Purity: ≥97% (HPLC)
Packaging: 5mg
Price: $47
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0954
Product name: Thiocolchicine
Purity: ≥97% (HPLC)
Packaging: 25mg
Price: $192
Updated: 2024/03/01

Cayman Chemical

Product number: 17427
Product name: Thiocolchicine
Purity: ≥98%
Packaging: 5mg
Price: $38
Updated: 2024/03/01

Cayman Chemical

Product number: 17427
Product name: Thiocolchicine
Purity: ≥98%
Packaging: 10mg
Price: $71
Updated: 2024/03/01

Cayman Chemical

Product number: 17427
Product name: Thiocolchicine
Purity: ≥98%
Packaging: 25mg
Price: $166
Updated: 2024/03/01

More

Less

thiocolchicine Chemical Properties,Usage,Production

Chemical Properties

Bright Yellow Solid

Uses

A muscle relaxant.

Biochem/physiol Actions

Thiocolchicine is an antimitotic alkaloid and apoptosis inducer that inhibits tubulin polymerization and microtubule assembly.

thiocolchicine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

thiocolchicine Suppliers

Canada 1 China 63 France 1 India 5 United States 9 Global 79

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

Cato Research Chemicals Inc.

Tel: 020-81960175
Fax: +1-541-2553641
Email: min.he@cato-chem.com
Country: China
ProdList: 1955
Advantage: 55

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Wuhan ChemFaces Biochemical Co., Ltd.

Tel: 18607101326 15172504745
Fax: +86-27-84254680
Email: aileen@chemfaces.com
Country: China
ProdList: 6905
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57423
Advantage: 58

2730-71-4, thiocolchicineRelated Search:

thiocolchicine

thiocholchicine

(S)-7-Acetylamino-6,7-dihydro-10-methylthio-1,2,3-trimethoxybenzo[a]heptalen-9(5H)-one

(S)-7α-Acetylamino-6,7-dihydro-10-(methylthio)-1,2,3-trimethoxybenzo[a]heptalene-9(5H)-one

10-Demethoxy-10-methylthiocolchicine

10-Thiocolchicine

N-[(S)-5,6,7,9-Tetrahydro-1,2,3-trimethoxy-10-methylthio-9-oxobenzo[a]heptalen-7-yl]acetamide

N-[(7S)-5,6,7,9-Tetrahydro-1,2,3-triMethoxy-10-(Methylthio)-9-oxobenzo[a]heptalen-7-yl]acetaMide

NSC 186301

(S)-N-(1,2,3-trimethoxy-10-(methylthio)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide

Thiocolchicoside EP Impurity B

Acetamide, N-[(7S)-5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-

breast,LoVo/DX,MDR-positive,Microtubule/Tubulin,inhibit,MCF-7,leukemia,Colchicine,Apoptosis,BALB/3T3,cancer,A-549,LoVo,Thiocolchicine,Analogue,Inhibitor

N-[(7S,12aRa)-1,2,3-trimethoxy-10-(methylsulfanyl)-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide (thiocolchicine)

Thiocolchicine, 10 mM in DMSO

2730-71-4

Intermediates & Fine Chemicals

Pharmaceuticals