2-Methoxy-5-fluoro-4-aminopyrimidine
- Product Name
- 2-Methoxy-5-fluoro-4-aminopyrimidine
- CAS No.
- 1993-63-1
- Chemical Name
- 2-Methoxy-5-fluoro-4-aminopyrimidine
- Synonyms
- 5-Fluoro-2-MethoxypyriMidin-4-aMine;5-Fluoro-2-methoxy-4-pyrimidinamine;4-AMINO-5-FLUORO-2-METHOXYPYRIMIDINE;2-Methoxy-5-fluoro-4-aminopyrimidine;4-Pyrimidinamine, 5-fluoro-2-methoxy;5-Fluoro-2-methoxy-pyrimidin-4-ylamine;4-Amino-5-fluoro-2-methoxypyrimidine >4-Pyrimidinamine, 5-fluoro-2-methoxy- (9CI);2-Methoxy-5-fluoro-4-aminopyrimidine ISO 9001：2015 REACH;2-methoxy-5-fluoro-4-aminopyrimidine (intermediate of flucytosine)
- CBNumber
- CB1946996
- Molecular Formula
- C5H6FN3O
- Formula Weight
- 143.12
- MOL File
- 1993-63-1.mol
2-Methoxy-5-fluoro-4-aminopyrimidine Property
- Melting point:
- 193 °C
- Boiling point:
- 278.9±43.0 °C(Predicted)
- Density
- 1.345±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- powder to crystal
- pka
- 3.63±0.10(Predicted)
- color
- White to Almost white
- InChI
- InChI=1S/C5H6FN3O/c1-10-5-8-2-3(6)4(7)9-5/h2H,1H3,(H2,7,8,9)
- InChIKey
- BYALTIIVASWNSY-UHFFFAOYSA-N
- SMILES
- C1(OC)=NC=C(F)C(N)=N1
- CAS DataBase Reference
- 1993-63-1
Safety
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- A2125
- Product name
- 4-Amino-5-fluoro-2-methoxypyrimidine
- Purity
- >99.0%(T)
- Packaging
- 5g
- Price
- $317
- Updated
- 2025/07/31
- Product number
- F599353
- Product name
- 5-Fluoro-2-methoxypyrimidin-4-amine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- PC906580
- Product name
- 4-Amino-5-fluoro-2-methoxypyrimidine
- Purity
- 95%
- Packaging
- 1g
- Price
- $105
- Updated
- 2021/12/16
- Product number
- Z4372
- Product name
- 5-Fluoro-2-methoxypyrimidin-4-amine
- Packaging
- 10g
- Price
- $191
- Updated
- 2021/12/16
- Product number
- PC906580
- Product name
- 4-Amino-5-fluoro-2-methoxypyrimidine
- Purity
- 95%
- Packaging
- 5g
- Price
- $230
- Updated
- 2021/12/16
2-Methoxy-5-fluoro-4-aminopyrimidine Chemical Properties,Usage,Production
Synthesis
1801-06-5
1993-63-1
General procedure for the synthesis of 5-fluoro-2-methoxy-4-fluoropyrimidinamine using 2-methoxy-4-chloro-5-fluoropyrimidine as starting material: 32.5 g of 2-methoxy-4-chloro-5-fluoropyrimidine (compound of formula III) was added to 170 g of a 10 wt% solution of isopropanol in ammonia, heated to 40-60 °C, and the reaction was stirred for 3-5 hours. After completion of the reaction, it was naturally cooled to room temperature and the solid product was collected by filtration. The solid was washed with isopropanol and dried to give 27.2 g of 5-fluoro-2-methoxy-4-pyrimidinamine (compound of formula II, white solid) in 95.0% molar yield and 99.0% HPLC purity.
References
[1] Patent: CN105272922, 2016, A. Location in patent: Paragraph 0038; 0039; 0040
2-Methoxy-5-fluoro-4-aminopyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Methoxy-5-fluoro-4-aminopyrimidine Suppliers
- Tel
- --
- Fax
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- Country
- United Kingdom
- ProdList
- 6309
- Advantage
- 46
View Lastest Price from 2-Methoxy-5-fluoro-4-aminopyrimidine manufacturers
- Product
- 2-Methoxy-5-fluoro-4-aminopyrimidine 1993-63-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-26
- Product
- 2-Methoxy-5-fluoro-4-aminopyrimidine 1993-63-1
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98.00%
- Supply Ability
- 20tons
- Release date
- 2023-09-08