ChemicalBook > CAS DataBase List > 4-Bromo-6-fluoroquinoline
4-Bromo-6-fluoroquinoline
- Product Name
- 4-Bromo-6-fluoroquinoline
- CAS No.
- 661463-17-8
- Chemical Name
- 4-Bromo-6-fluoroquinoline
- Synonyms
- 4-Bromo-6-fluoroquinoline;Quinoline, 4-bromo-6-fluoro-
- CBNumber
- CB1948011
- Molecular Formula
- C9H5BrFN
- Formula Weight
- 226.05
- MOL File
- 661463-17-8.mol
More
Less
4-Bromo-6-fluoroquinoline Property
- Boiling point:
- 299.7±20.0 °C(Predicted)
- Density
- 1.647±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- pka
- 2.71±0.16(Predicted)
- Appearance
- Colorless to yellow Solid
- InChIKey
- HIWPTYUKGHNQCU-UHFFFAOYSA-N
More
Less
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H318Causes serious eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- BBO000278
- Product name
- 4-Bromo-6-fluoroquinoline
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $356
- Updated
- 2025/07/31
TRC
- Product number
- B804385
- Product name
- 4-bromo-6-fluoroquinoline
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
Apolloscientific
- Product number
- PC404567
- Product name
- 4-Bromo-6-fluoroquinoline
- Packaging
- 1g
- Price
- $285
- Updated
- 2021/12/16
AK Scientific
- Product number
- 7568BB
- Product name
- 4-Bromo-6-fluoroquinoline
- Packaging
- 5g
- Price
- $377
- Updated
- 2021/12/16
SynQuest Laboratories
- Product number
- 3H32-B-0G
- Product name
- 4-Bromo-6-fluoroquinoline
- Packaging
- 1g
- Price
- $456
- Updated
- 2021/12/16
More
Less
4-Bromo-6-fluoroquinoline Chemical Properties,Usage,Production
Synthesis
391-78-6
661463-17-8
General procedure for the synthesis of 4-bromo-6-fluoroquinoline from 4-hydroxy-6-fluoroquinoline: To a solution of 4-hydroxy-6-fluoroquinoline (20 g, 122.58 mmol) in DMF (130 mL) heated to 60 °C was slowly added phosphorus tribromide (13 mL, 1.15 equiv.). The reaction mixture was heated at 45 °C with stirring for 45 min. After the reaction was completed, it was cooled to room temperature and the reaction solution was diluted with water (200 mL). Subsequently, Na2CO3 was slowly added until the pH of the reaction solution reached 10. The precipitated solid product was collected by filtration. The solid was dissolved in ethyl acetate (200 mL) and the solution was concentrated to dryness. The residue was purified by column chromatography (eluent: ethyl acetate) to afford the target product 4-bromo-6-fluoroquinoline as a pale yellow solid (22 g, 79% yield).1H NMR (CDCl3) δ: 8.70 (d, J = 4.7 Hz, 1H); 8.14 (m, 1H); 7.96 (d, J = 4.7 Hz, 1H); 7.81-7.73 (m 2H).
References
[1] Patent: WO2008/152603, 2008, A1. Location in patent: Page/Page column 36
[2] Patent: WO2017/21319, 2017, A1. Location in patent: Page/Page column 32
4-Bromo-6-fluoroquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
4-Bromo-6-fluoroquinoline Suppliers
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 16077
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 18986259541
- Fax
- 027-87840182
- sales@3stc.com
- Country
- China
- ProdList
- 3764
- Advantage
- 58
- Tel
- 18030648795
- Fax
- 028-61777050
- sales@cdforestchem.com
- Country
- China
- ProdList
- 2000
- Advantage
- 58
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9510
- Advantage
- 58
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9342
- Advantage
- 55
- Tel
- 027-027-87342388 18086026008
- Fax
- 027-87342388
- sales@kaymke.com
- Country
- China
- ProdList
- 3731
- Advantage
- 55
- Tel
- 0512-62857507
- Fax
- +86-512-62857507
- sales@sinorarechem.com
- Country
- China
- ProdList
- 998
- Advantage
- 58
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 0512-62968256 18550502935
- Fax
- 0512-62968256
- export@laingbiotec.com
- Country
- China
- ProdList
- 981
- Advantage
- 58
- Tel
- 13661411401
- Fax
- 51370935-8011
- yinglv.que@aqbiopharma.com.cn
- Country
- China
- ProdList
- 2930
- Advantage
- 58
- Tel
- 微信 17321281695 18019252918
- Fax
- 17321281695
- sale@amkchem.com
- Country
- China
- ProdList
- 15136
- Advantage
- 55
- Tel
- 025-57018978 18251899859
- Fax
- 025-57018008
- sales@chalf-pharm.com
- Country
- China
- ProdList
- 5674
- Advantage
- 50
- Tel
- 13817873692
- Fax
- 021-31329586
- mkt@boynerspharm.com
- Country
- China
- ProdList
- 1707
- Advantage
- 55
- Tel
- 021-58088081 Q2635253576
- Fax
- QQ3382968513
- hailey@shsendpharm.com
- Country
- China
- ProdList
- 2081
- Advantage
- 55
- Tel
- 028-88469284 18000562381
- rzbtsj@163.com
- Country
- China
- ProdList
- 9951
- Advantage
- 56
- Tel
- 0570-3081766 18357083060
- Fax
- 0570-3072337
- sales@qzamkbio.com
- Country
- China
- ProdList
- 1051
- Advantage
- 55
- Tel
- 028-86040038 13980902949;
- Fax
- 028-85149890
- market@dingdangchem.com
- Country
- China
- ProdList
- 1853
- Advantage
- 55
- Tel
- 0311-89250318 031166536426
- Fax
- 4000311741
- master@sjzsdyn.com
- Country
- China
- ProdList
- 3495
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 0519-85528066 13775048983
- Fax
- 0519-85528066
- sales@hopschem.com
- Country
- China
- ProdList
- 31553
- Advantage
- 55
- Tel
- 025-83453382-8005
- Fax
- 025-83453382
- sale@parabiochem.com
- Country
- China
- ProdList
- 9595
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 021-20432229
- Fax
- QQ2412110556
- 2412110556@qq.com
- Country
- China
- ProdList
- 6017
- Advantage
- 55
- Tel
- 0371-55900031 18137872243
- Fax
- QQ：2853979815
- 2853979815@qq.com
- Country
- China
- ProdList
- 9996
- Advantage
- 55
- Tel
- +86-（0）57185586718; +8613336195806
- Fax
- +86-571-85864795
- sales@capot.com
- Country
- China
- ProdList
- 29735
- Advantage
- 60
- Tel
- 025-58859352 18068836627
- Fax
- (5)02557626880
- dt3@aikonchem.com
- Country
- China
- ProdList
- 15493
- Advantage
- 58
- Tel
- 400-8210725 400821072
- Fax
- 021-58955996
- malulu@leyan.com
- Country
- China
- ProdList
- 25000
- Advantage
- 58
- Tel
- 15981811963
- Fax
- QQ：1410472904
- 1410472904@qq.com
- Country
- China
- ProdList
- 5825
- Advantage
- 58
- Tel
- 025-83453327
- Fax
- 025-83453327
- product@chemlin.com.cn
- Country
- China
- ProdList
- 277
- Advantage
- 58
- Tel
- 025-83453353
- Fax
- 025-83453353
- nj.chemlin@chemlin.com.cn
- Country
- CHINA
- ProdList
- 853
- Advantage
- 58
- Tel
- 13370351217 kungfu1217@1
- Fax
- QQ1400885609
- kungfu1217@163.com
- Country
- China
- ProdList
- 2720
- Advantage
- 58
- Tel
- 0371-63315541 13323832564
- Fax
- QQ:3001332135
- 3001332135@qq.com
- Country
- China
- ProdList
- 9972
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58
- Tel
- 028-87925786 18010564218
- Fax
- 028-61777050
- vendi@cdforestchem.com
- Country
- China
- ProdList
- 1992
- Advantage
- 58
- Tel
- +86-023-62871537
- sales@rosewachem.com
- Country
- China
- ProdList
- 2803
- Advantage
- 58
- Tel
- 0512-65816829 18662214788
- Fax
- 0512-65816829
- info@rovathin.com.cn
- Country
- China
- ProdList
- 9987
- Advantage
- 58
- Tel
- +86-400-0216110 +86-15958047586
- Fax
- 0086-21-33275002
- sales@allfluoro.com
- Country
- China
- ProdList
- 11385
- Advantage
- 58
- Tel
- +86-13916956214
- sales@victory-pharm.com
- Country
- China
- ProdList
- 1299
- Advantage
- 58
- Tel
- +86-27-50766799 +8618062016861
- contact@labnetwork.com
- Country
- China
- ProdList
- 19987
- Advantage
- 58
- Tel
- 18516099287
- 3045383737@qq.com
- Country
- China
- ProdList
- 230
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- Fax
- 0086-371-86658258
- factory@coreychem.com
- Country
- China
- ProdList
- 29798
- Advantage
- 58
- Tel
- 0531-0531-88163906-805-805 15588346797
- fanbomedical@163.com
- Country
- China
- ProdList
- 564
- Advantage
- 58
- Tel
- +8613580539051
- joe@yuhengpharm.com
- Country
- CHINA
- ProdList
- 21142
- Advantage
- 58
- Tel
- nanfengdrug@163.com; 18616377689
- nanfengdrug@163.com
- Country
- China
- ProdList
- 20009
- Advantage
- 58
- Tel
- 0519-68985668 13685222090
- Fax
- qq735434464
- sales@kechem.cn
- Country
- China
- ProdList
- 26028
- Advantage
- 58
- Tel
- 1701086315
- Fax
- 1701086315@qq.com
- dexuanpharma@126.com
- Country
- China
- ProdList
- 9475
- Advantage
- 58
- Tel
- 021-51816796-820 13611835272
- Fax
- 021-5161 3951
- sales2@sunwaypharm.com
- Country
- China
- ProdList
- 44119
- Advantage
- 58
- Tel
- 18939844854
- Fax
- QQ3004479448
- sales6@myuchem.com
- Country
- China
- ProdList
- 4997
- Advantage
- 58
- Tel
- 0574-87314919 057487319282
- info@nbinno.com
- Country
- China
- ProdList
- 7047
- Advantage
- 58
More
Less
View Lastest Price from 4-Bromo-6-fluoroquinoline manufacturers
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
- Product
- 4-Bromo-6-fluoroquinoline 661463-17-8
- Price
- US $1.10-9.90/KG
- Min. Order
- 1KG
- Purity
- 99% min
- Supply Ability
- 100kg
- Release date
- 2025-08-18
Career Henan Chemical Co
- Product
- 4-Bromo-6-fluoroquinoline 661463-17-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-07
661463-17-8, 4-Bromo-6-fluoroquinolineRelated Search:
4-Bromo-6-chloroquinoline
4-BROMO-6-METHOXYQUINOLINE
4-Bromo-6-methylquinoline
4-broMo-6-MethoxypyriMidine
4-Bromo-6-methoxyquinoline-3-carboxylic acid ethyl ester
4-BroMo-6,7-diMethoxyquinazoline
4-Bromo-6-(trifluoromethyl)quinoline
4-Bromo-6-fluoroquinoline