Boc-S-trityl-D-cysteine

Product Name: Boc-S-trityl-D-cysteine
CAS No.: 87494-13-1
Chemical Name: Boc-S-trityl-D-cysteine
Synonyms: Boc-Cys(trt)-OH;BOC-D-CYS(TRT)-OH 98%;Boc-S-trityl-D-cysteine;N-Boc-S-trityl-D-cysteine;Boc-D-Cys(Trt)-OH（non-animal）;N-Boc-S-trityl-D-cysteine, 98%;Boc-S-trityl-D-cysteine USP/EP/BP;(Tert-Butoxy)Carbonyl D-Cys(Trt)-OH;Boc-S-trityl-D-cysteine≥ 99% (HPLC);Boc-D-Cys(Trt)-OH Boc-S-trityl-D-cysteine
CBNumber: CB1966770
Molecular Formula: C27H29NO4S
Formula Weight: 463.59
MOL File: 87494-13-1.mol

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Boc-S-trityl-D-cysteine Property

Melting point:: 146-149°C
Boiling point:: 610.9±55.0 °C(Predicted)
Density: 1.200±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: Chloroform (Slightly), DMSO (Slightly), Ethanol (Sparingly)
form: Solid
pka: 3.82±0.10(Predicted)
color: White to Off-White
CAS DataBase Reference: 87494-13-1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: B600660
Product name: Boc-D-Cys(Trt)-OH
Packaging: 5g
Price: $150
Updated: 2021/12/16

Chem-Impex

Product number: 05484
Product name: Boc-S-trityl-D-cysteine,99%(HPLC)
Purity: 99%(HPLC)
Packaging: 1G
Price: $11.2
Updated: 2021/12/16

Chem-Impex

Product number: 05484
Product name: Boc--trityl-D-cysteine
Purity: ≥ 99% (HPLC)
Packaging: 5G
Price: $35
Updated: 2021/12/16

AK Scientific

Product number: X5764
Product name: Boc-D-Cys(Trt)-OH
Packaging: 5g
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB48462
Product name: Boc-S-trityl-D-cysteine
Packaging: 2g
Price: $104.3
Updated: 2021/12/16

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Boc-S-trityl-D-cysteine Chemical Properties,Usage,Production

Uses

Boc-Cys(Trt)-OH is used in method for preparing ularitide.

reaction suitability

reaction type: Boc solid-phase peptide synthesis

Synthesis

24424-99-5

2799-07-7

21947-98-8

General procedure for the synthesis of N-tert-butoxycarbonyl-S-trityl-L-cysteine from di-tert-butyl dicarbonate and S-trityl-L-cysteine: to a solution of 2N NaOH (80 mL) of S-trityl-L-cysteine (5 g, 12.7 mmol) was added di-tert-butyl dicarbonate (4.5 g, 20 mmol), and the reaction mixture was at room temperature The reaction mixture was stirred for 24 hours at room temperature. Upon completion of the reaction, the aqueous solution was acidified to pH 2 with concentrated HCl and then extracted with CH2Cl2 (2 x 100 mL). The organic phases were combined, washed with brine, dried and concentrated under reduced pressure to give N-Boc-S-trityl-L-cysteine (5.3 g, 90%) as a white foam, which did not need to be further purified.1H NMR (DMSO): δ (ppm) 1.37 (s, 9H, 3 × CH3); 2.29-2.58 (m, 2H, CH2); 3.76- 3.79 (m, 1H, CH); 6.84 (d, J = 7.8 Hz, 1H, NH); 7.14-7.38 (m, 15H, triphenylmethyl-H).MALDI-TOF MS: m/z 464.8 Da [M + H], C27H29NO4S, molecular weight: 463.59.

References

[1] European Journal of Medicinal Chemistry, 2012, vol. 50, p. 383 - 392
[2] Chemical Communications, 2013, vol. 49, # 92, p. 10808 - 10810
[3] Patent: CN106432014, 2017, A. Location in patent: Paragraph 0096; 0100; 0101; 0102; 0142; 0146; 0147; 0148
[4] Patent: WO2009/137251, 2009, A2. Location in patent: Page/Page column 30; 31
[5] Chemistry of Natural Compounds, 1979, vol. 15, p. 471 - 476

Boc-S-trityl-D-cysteine Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-S-trityl-D-cysteine Suppliers

China 114 Germany 3 India 2 Japan 2 United Kingdom 1 United States 16 Global 138

Meryer (Shanghai) Chemical Technology Co., Ltd.

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Alfa Aesar

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Jia Xing Isenchem Co.,Ltd

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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky (shanghai) International Co.,Ltd

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China DongFan Chemical Co.,LTD

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ChemPep, Inc.

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Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
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Country: China
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9ding chemical ( Shanghai) Limited

Tel: 4009209199
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View Lastest Price from Boc-S-trityl-D-cysteine manufacturers

Career Henan Chemical Co

Product: Boc-S-trityl-D-cysteine 87494-13-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-14

87494-13-1, Boc-S-trityl-D-cysteineRelated Search:

N-(tert-Butoxycarbonyl)-L-alanine FMOC-D-alanine Nalpha-Fmoc-Ndelta-trityl-L-glutamine Fmoc-Asn(Trt)-OH FMOC-CYS(MMT)-OH FMOC-S-trityl-L-cysteine Fmoc-S-acetamidomethyl-L-cysteine BOC-D-Alanine Boc-beta-cyclohexyl-D-alanine monohydrate Boc-D-aspartic acid 4-benzyl ester BOC-D-Cysteine (Boc-D-Cys-OH ) Boc-D-aspartic acid 4-cyslohexyl ester BOC-D-ASP(OTBU)-OH DCHA Boc-alpha-Cyclohexyl-D-glycine BOC-D-ASP(OBZL)-OH N-Boc-S-Trityl-L-cysteine

N-alpha-t-Butyloxycarbonyl-S-trityl-D-cysteine

Boc-S-trityl-D-cysteine

Boc-Cys(trt)-OH

Boc-D-Cys(Trt)-OH Boc-S-trityl-D-cysteine

N-Boc-S-trityl-D-cysteine, 98%

(S)-2-(Tert-butoxycarbonylamino)-3-(tritylthio)propanoic acid

Boc-S-trityl-D-cysteine≥ 99% (HPLC)

(Tert-Butoxy)Carbonyl D-Cys(Trt)-OH

(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[(triphenylmethyl)sulfanyl]propanoic acid

N-alpha-tert-Butyloxycarbonyl-s-trityl-D-cysteine

D-?Cysteine, N-?[(1,?1-?dimethylethoxy)?carbonyl]?-?S-?(triphenylmethyl)?-

Boc-D-Cys(Trt)-OH（non-animal）

Boc-S-trityl-D-cysteine USP/EP/BP

(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-tritylsulfanylpropanoic acid

2-{[(tert-butoxy)carbonyl]amino}-3-[(triphenylmethyl)sulfanyl]propanoic acid

N-[(1,1-Dimethylethoxy)carbonyl]-S-(triphenylmethyl)-D-cysteine

BOC-D-CYS(TRT)-OH 98%

N-Boc-S-trityl-D-cysteine

87494-13-1

Amino Acids