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FMOC-S-trityl-L-cysteine

Product Name
FMOC-S-trityl-L-cysteine
CAS No.
103213-32-7
Chemical Name
FMOC-S-trityl-L-cysteine
Synonyms
FMOC-CYS(TRT)-OH;FMOC-CYS(TRT);FMOC-L-CYS(TRT)-OH;Fomc-Cys(Trt)-OH;N-FMOC-S-TRITYL-L-CYSTEINE;Fmoc-Cyc(Trt)-OH;FMOC-L-CYS(TRT);Fmoc-Cys(Trt)-0H;FMOC-L-CYS(TRITYL);FMOC Cysteine (trt)
CBNumber
CB2138770
Molecular Formula
C37H31NO4S
Formula Weight
585.71
MOL File
103213-32-7.mol
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FMOC-S-trityl-L-cysteine Property

Melting point:
170-173 °C(lit.)
alpha 
16 º (c=1, THF)
Boiling point:
763.4±60.0 °C(Predicted)
Density 
1.270±0.06 g/cm3(Predicted)
refractive index 
18 ° (C=1, THF)
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka
3.70±0.10(Predicted)
form 
Powder
color 
White to almost white
optical activity
[α]20/D +16.0±2°, c = 1% in THF
Water Solubility 
Insoluble in water. Soluble in most organic solvents.
BRN 
4221286
InChIKey
KLBPUVPNPAJWHZ-UMSFTDKQSA-N
CAS DataBase Reference
103213-32-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-26
WGK Germany 
3
F 
9-21
Hazard Note 
Irritant
HS Code 
29309090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.52008
Product name
Fmoc-Cys(Trt)-OH
Purity
Novabiochem?
Packaging
25g
Price
$74.8
Updated
2025/07/31
Sigma-Aldrich
Product number
8.52008
Product name
Fmoc-Cys(Trt)-OH
Purity
Novabiochem?
Packaging
100g
Price
$188
Updated
2025/07/31
Sigma-Aldrich
Product number
8.52008
Product name
Fmoc-Cys(Trt)-OH
Purity
Novabiochem?
Packaging
250g
Price
$375
Updated
2025/07/31
Sigma-Aldrich
Product number
8.52008
Product name
Fmoc-Cys(Trt)-OH
Purity
Novabiochem<SUP>&#174;</SUP>
Packaging
500 g
Price
$718
Updated
2025/07/31
Sigma-Aldrich
Product number
8.52008
Product name
Fmoc-Cys(Trt)-OH
Purity
Novabiochem<SUP>&#174;</SUP>
Packaging
500 g
Price
$718
Updated
2025/07/31
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FMOC-S-trityl-L-cysteine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative used in peptide synthesis. Some of the examples are:

  • Synthesis of mono- and bi-functionalized platinum(IV) complexes to target angiogenic tumor vasculature.
  • Synthesis of proteins through native chemical ligation of peptide hydrazides as thioester surrogates via solid-phase synthesis.
  • Synthesis of glycoconjugates by conjugating reducing sugars to cysteine residues of peptides.

Uses

FMOC-S-trityl-L-cysteine is potentially useful for proteomics studies, and solid phase peptide synthesis techniques. The compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function.

General Description

The standard derivative for Fmoc SPPS of peptides containing Cys [1]. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation [2,3] to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP®, is to be employed, it is strongly recommended that collidine is used as the base [4], as this has been shown to significantly reduce loss of optical integrity during coupling.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

FMOC-S-trityl-L-cysteine Preparation Products And Raw materials

Raw materials

Preparation Products

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FMOC-S-trityl-L-cysteine Suppliers

Americas 1 Belgium 2 Canada 2 China 384 Europe 6 France 2 Germany 7 Hungary 1 India 16 Italy 2 Japan 9 Poland 1 South Korea 1 Switzerland 7 United Kingdom 18 United States 65 Global 524
Lanxi Xingnuo Import and Export Trading Co., Ltd
Tel
0579-8831088 15888978871
Email
994350525@qq.com
Country
China
ProdList
23
Advantage
58
Jiangsu Jitai Peptide Technology Co., Ltd.
Tel
0515-8085-5066 13770132022
Email
sales05@gtaipeptide.com
Country
China
ProdList
2675
Advantage
58
Gill polypeptide biopharmaceutical (dalian) co., LTD
Tel
021-61263455 13167021076
Email
amy@glschina.com
Country
China
ProdList
9737
Advantage
58
Chengdu Tachem Co., Ltd
Tel
19983060238
Email
sales@tachem.cn
Country
China
ProdList
103
Advantage
58
shanghai Yanfeng biochemical technology Co.,LTD
Tel
17721070236 13611955358;
Email
yanfen2023@126.com
Country
China
ProdList
2393
Advantage
58
SICHUAN TONGSHENG BIOPHARMACEUTICAL CO., LTD
Tel
0838-2809458 13350585791
Email
pharm@biots.cn
Country
China
ProdList
589
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58
Chengdu ZY Biochemical Technology Co., Ltd.
Tel
88680086 13398185735
Email
fengzilong@zybiochem.com
Country
China
ProdList
177
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58
Shanghai Troedsson Technology Co., LTD
Tel
18117455885
Email
qihongchem@163.com
Country
China
ProdList
9092
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
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View Lastest Price from FMOC-S-trityl-L-cysteine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Fmoc-Cys(Trt)-OH 103213-32-7
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500kgs
Release date
2021-09-26
Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Fmoc-L-Cys(trt)-OH 103213-32-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2023-11-13
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Fmoc-L-Cys(trt)-OH 103213-32-7
Price
US $50.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-12-02

103213-32-7, FMOC-S-trityl-L-cysteineRelated Search:

ALTRENOGEST METHOXYCARBONYLSULFENYL CHLORIDE Fmoc-Lys(Boc)-OH Triphenylmethyl Chloride Fmoc-Phe-OH p-Toluenesulfonic acid 9-Fluorenylmethyl chloroformate 6-Aminocaproic acid Glycine L-Fmoc-Aspartic acid alpha-tert-butyl ester PYRAZOPHOS L-Cysteine Trityl candesartan cilexetil Trityl Irbesartan CARBONYL SULFIDE Propionic acid Fmoc-OSu Tris(hydroxymethyl)aminomethane

  • FMOC-CYSTEINE(TRT)-OH
  • FMOC-CYS(TRT)
  • FMOC-CYS(TRT)-OH
  • FMOC-L-CYSTEINE(TRITYL)
  • FMOC-L-CYSTEINE (TRT)
  • FMOC-L-CYS(TRITYL)
  • FMOC-L-CYS(TRT)
  • FMOC-L-CYS(TRT)-OH
  • FMOC-S-TRITYL-L-CYSTEINE
  • 2-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO]-3-(TRITYLTHIO)PROPANOIC ACID
  • L-CYSTEINE-N-FMOC, S-TRITYL
  • 9-FLUORENYLMETHOXYCARBONYL-S-TRITYL-L-CYSTEINE
  • S-TRITYL-L-CYSTEINE, N-FMOC PROTECTED
  • N-ALPHA-FMOC-S-TRITYL-L-CYSTEINE
  • N-(9-FLUORENYL METHOXY CARBONYL)-S-TRITYL-L-CYSTEINE
  • N-9-FLUORENYLMETHYLOXYCARBONYL-S-TRITYL-L-CYSTEINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-S-TRITYL-L-CYSTEINE
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-S-TRITYL-L-CYSTEINE
  • N-FMOC-L-CYS(TRT)-OH
  • N-FMOC-S-TRITYL-L-CYSTEINE
  • (R)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-TRITYLSULFANYL-PROPIONIC ACID
  • FMoc-Cys(Trt)-OH FMoc-S-trityl-L-cysteine
  • N-Fmoc-S-trityl-L-cysteine Fmoc-Cys(Trt)-OH
  • (R)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(tritylthio)propanoic acid
  • (R)-(9H-Fluoren-9-yl)methyl (1-hydroxy-3-(tritylthio)propan-2-yl)carbamate
  • Fmoc-Cys(Trt)-OH >=95.0% (sum of enantiomers, HPLC)
  • Fmoc-Cys(Trt)-OH, >=99%
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Cys(Trt)-OH (Cys of Non-Animal Origin)
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Cys(Trt)-OH (Cys of Animal Origin)
  • Fomc-Cys(Trt)-OH
  • (R)-2-Fmoc-3-tritylsulfanyl-propionic acid
  • Fmoc-S-trityl-L-cysteine≥ 99.7% (HPLC, Chiral purity)
  • Fmoc-Cys(Trt)-OH(Animal origin)
  • Fmoc-Cys(Trt)-OH(Non-Animal origin)
  • (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[(triphenylmethyl)sulfanyl]propanoic acid
  • (2S)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-[(triphenylmethyl)thio]propanoate
  • n-(alpha)-fluorenylmethyloxycarbonyl-s-tritylcysteine
  • N<SUB>α</SUB>-Fmoc-S-trityl-L-cysteine
  • N-(9-FLUORENYLMETHOXYCARBONYL)-S-
  • FMOC-CYS(TRT)-OH, 98+%
  • N-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cystei
  • L-Cysteine-3,3-D2-N-FMOC-S-Trityl
  • L-Cysteine-N-FMOC-UL-13C3, 15N, S-Trityl
  • N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-S-(TRIPHENYLMETHYL)-L-CYSTEINE
  • FMOC-S-TRITYL-L-CYSTEINE (FMOC-L-CYS(TRT)-OH)
  • (R)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)cysteine
  • (9-fluorenylmethoxycarbonyl)-L-cysteine (trityl)
  • N-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cysteine, Nα-Fmoc-S-trityl-L-cysteine
  • Nα-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cysteine ,98%
  • N-[(9H-Fluoren-9-yloxy)carbonyl]-S-trityl-L-cysteine
  • FMOC-S-trityl-L-Cysteine,97%
  • Nα-Fmoc-S-trityl-L-c
  • S-Trityl-N-Fomc_L-Cysteine
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-L-cysteine&gt
  • FMOC-CYS(TRT)-OH 25 G
  • FMOC-CYS(TRT)-OH 100 G
  • FMOC-CYS(TRT)-OH 250 G
  • L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-