ChemicalBook > CAS DataBase List > FMOC-S-trityl-L-cysteine

FMOC-S-trityl-L-cysteine

Product Name: FMOC-S-trityl-L-cysteine
CAS No.: 103213-32-7
Chemical Name: FMOC-S-trityl-L-cysteine
Synonyms: FMOC-CYS(TRT)-OH;FMOC-CYS(TRT);FMOC-L-CYS(TRT)-OH;Fomc-Cys(Trt)-OH;N-FMOC-S-TRITYL-L-CYSTEINE;Fmoc-Cyc(Trt)-OH;FMOC-L-CYS(TRT);Fmoc-Cys(Trt)-0H;FMOC-L-CYS(TRITYL);FMOC Cysteine (trt)
CBNumber: CB2138770
Molecular Formula: C37H31NO4S
Formula Weight: 585.71
MOL File: 103213-32-7.mol

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FMOC-S-trityl-L-cysteine Property

Melting point:: 170-173 °C(lit.)
alpha: 16 º (c=1, THF)
Boiling point:: 763.4±60.0 °C(Predicted)
Density: 1.270±0.06 g/cm3(Predicted)
refractive index: 18 ° (C=1, THF)
storage temp.: 2-8°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka: 3.70±0.10(Predicted)
form: Powder
color: White to almost white
optical activity: [α]20/D +16.0±2°, c = 1% in THF
Water Solubility: Insoluble in water. Soluble in most organic solvents.
BRN: 4221286
InChIKey: KLBPUVPNPAJWHZ-UMSFTDKQSA-N
CAS DataBase Reference: 103213-32-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-26
WGK Germany: 3
F: 9-21
Hazard Note: Irritant
HS Code: 29309090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.52008
Product name: Fmoc-Cys(Trt)-OH
Purity: Novabiochem?
Packaging: 25g
Price: $74.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.52008
Product name: Fmoc-Cys(Trt)-OH
Purity: Novabiochem?
Packaging: 100g
Price: $188
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.52008
Product name: Fmoc-Cys(Trt)-OH
Purity: Novabiochem?
Packaging: 250g
Price: $375
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.52008
Product name: Fmoc-Cys(Trt)-OH
Purity: Novabiochem®
Packaging: 500 g
Price: $718
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.52008
Product name: Fmoc-Cys(Trt)-OH
Purity: Novabiochem®
Packaging: 500 g
Price: $718
Updated: 2025/07/31

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FMOC-S-trityl-L-cysteine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative used in peptide synthesis. Some of the examples are:

Synthesis of mono- and bi-functionalized platinum(IV) complexes to target angiogenic tumor vasculature.
Synthesis of proteins through native chemical ligation of peptide hydrazides as thioester surrogates via solid-phase synthesis.
Synthesis of glycoconjugates by conjugating reducing sugars to cysteine residues of peptides.

Uses

FMOC-S-trityl-L-cysteine is potentially useful for proteomics studies, and solid phase peptide synthesis techniques. The compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function.

General Description

The standard derivative for Fmoc SPPS of peptides containing Cys [1]. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation [2,3] to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP^®, is to be employed, it is strongly recommended that collidine is used as the base [4], as this has been shown to significantly reduce loss of optical integrity during coupling.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

FMOC-S-trityl-L-cysteine Preparation Products And Raw materials

Raw materials

Preparation Products

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FMOC-S-trityl-L-cysteine Suppliers

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View Lastest Price from FMOC-S-trityl-L-cysteine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Fmoc-Cys(Trt)-OH 103213-32-7
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 500kgs
Release date: 2021-09-26

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Fmoc-L-Cys(trt)-OH 103213-32-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T
Release date: 2023-11-13

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Fmoc-L-Cys(trt)-OH 103213-32-7
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-12-02

103213-32-7, FMOC-S-trityl-L-cysteineRelated Search:

ALTRENOGEST METHOXYCARBONYLSULFENYL CHLORIDE Fmoc-Lys(Boc)-OH Triphenylmethyl Chloride Fmoc-Phe-OH p-Toluenesulfonic acid 9-Fluorenylmethyl chloroformate 6-Aminocaproic acid Glycine L-Fmoc-Aspartic acid alpha-tert-butyl ester PYRAZOPHOS L-Cysteine Trityl candesartan cilexetil Trityl Irbesartan CARBONYL SULFIDE Propionic acid Fmoc-OSu Tris(hydroxymethyl)aminomethane

FMOC-CYSTEINE(TRT)-OH

FMOC-CYS(TRT)

FMOC-CYS(TRT)-OH

FMOC-L-CYSTEINE(TRITYL)

FMOC-L-CYSTEINE (TRT)

FMOC-L-CYS(TRITYL)

FMOC-L-CYS(TRT)

FMOC-L-CYS(TRT)-OH

FMOC-S-TRITYL-L-CYSTEINE

2-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO]-3-(TRITYLTHIO)PROPANOIC ACID

L-CYSTEINE-N-FMOC, S-TRITYL

9-FLUORENYLMETHOXYCARBONYL-S-TRITYL-L-CYSTEINE

S-TRITYL-L-CYSTEINE, N-FMOC PROTECTED

N-ALPHA-FMOC-S-TRITYL-L-CYSTEINE

N-(9-FLUORENYL METHOXY CARBONYL)-S-TRITYL-L-CYSTEINE

N-9-FLUORENYLMETHYLOXYCARBONYL-S-TRITYL-L-CYSTEINE

N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-S-TRITYL-L-CYSTEINE

N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-S-TRITYL-L-CYSTEINE

N-FMOC-L-CYS(TRT)-OH

N-FMOC-S-TRITYL-L-CYSTEINE

(R)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-TRITYLSULFANYL-PROPIONIC ACID

FMoc-Cys(Trt)-OH FMoc-S-trityl-L-cysteine

N-Fmoc-S-trityl-L-cysteine Fmoc-Cys(Trt)-OH

(R)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(tritylthio)propanoic acid

(R)-(9H-Fluoren-9-yl)methyl (1-hydroxy-3-(tritylthio)propan-2-yl)carbamate

Fmoc-Cys(Trt)-OH >=95.0% (sum of enantiomers, HPLC)

Fmoc-Cys(Trt)-OH, >=99%

(9H-Fluoren-9-yl)MethOxy]Carbonyl Cys(Trt)-OH (Cys of Non-Animal Origin)

(9H-Fluoren-9-yl)MethOxy]Carbonyl Cys(Trt)-OH (Cys of Animal Origin)

Fomc-Cys(Trt)-OH

(R)-2-Fmoc-3-tritylsulfanyl-propionic acid

Fmoc-S-trityl-L-cysteine≥ 99.7% (HPLC, Chiral purity)

Fmoc-Cys(Trt)-OH(Animal origin)

Fmoc-Cys(Trt)-OH(Non-Animal origin)

(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[(triphenylmethyl)sulfanyl]propanoic acid

(2S)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-[(triphenylmethyl)thio]propanoate

n-(alpha)-fluorenylmethyloxycarbonyl-s-tritylcysteine

Nα-Fmoc-S-trityl-L-cysteine

N-(9-FLUORENYLMETHOXYCARBONYL)-S-

FMOC-CYS(TRT)-OH, 98+%

N-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cystei

L-Cysteine-3,3-D2-N-FMOC-S-Trityl

L-Cysteine-N-FMOC-UL-13C3, 15N, S-Trityl

N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-S-(TRIPHENYLMETHYL)-L-CYSTEINE

FMOC-S-TRITYL-L-CYSTEINE (FMOC-L-CYS(TRT)-OH)

(R)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)cysteine

(9-fluorenylmethoxycarbonyl)-L-cysteine (trityl)

N-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cysteine, Nα-Fmoc-S-trityl-L-cysteine

Nα-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cysteine ,98%

N-[(9H-Fluoren-9-yloxy)carbonyl]-S-trityl-L-cysteine

FMOC-S-trityl-L-Cysteine,97%

Nα-Fmoc-S-trityl-L-c

S-Trityl-N-Fomc_L-Cysteine

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-L-cysteine&gt

FMOC-CYS(TRT)-OH 25 G

FMOC-CYS(TRT)-OH 100 G

FMOC-CYS(TRT)-OH 250 G

L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-