ChemicalBook > CAS DataBase List > FMOC-S-trityl-L-cysteine
FMOC-S-trityl-L-cysteine
- Product Name
- FMOC-S-trityl-L-cysteine
- CAS No.
- 103213-32-7
- Chemical Name
- FMOC-S-trityl-L-cysteine
- Synonyms
- FMOC-CYS(TRT)-OH;FMOC-CYS(TRT);FMOC-L-CYS(TRT)-OH;Fomc-Cys(Trt)-OH;N-FMOC-S-TRITYL-L-CYSTEINE;Fmoc-Cyc(Trt)-OH;FMOC-L-CYS(TRT);Fmoc-Cys(Trt)-0H;FMOC-L-CYS(TRITYL);FMOC Cysteine (trt)
- CBNumber
- CB2138770
- Molecular Formula
- C37H31NO4S
- Formula Weight
- 585.71
- MOL File
- 103213-32-7.mol
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FMOC-S-trityl-L-cysteine Property
- Melting point:
- 170-173 °C(lit.)
- alpha
- 16 º (c=1, THF)
- Boiling point:
- 763.4±60.0 °C(Predicted)
- Density
- 1.270±0.06 g/cm3(Predicted)
- refractive index
- 18 ° (C=1, THF)
- storage temp.
- 2-8°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- pka
- 3.70±0.10(Predicted)
- form
- Powder
- color
- White to almost white
- optical activity
- [α]20/D +16.0±2°, c = 1% in THF
- Water Solubility
- Insoluble in water. Soluble in most organic solvents.
- BRN
- 4221286
- InChIKey
- KLBPUVPNPAJWHZ-UMSFTDKQSA-N
- CAS DataBase Reference
- 103213-32-7(CAS DataBase Reference)
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 22-24/25-26
- WGK Germany
- 3
- F
- 9-21
- Hazard Note
- Irritant
- HS Code
- 29309090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 8.52008
- Product name
- Fmoc-Cys(Trt)-OH
- Purity
- Novabiochem?
- Packaging
- 25g
- Price
- $72.8
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 8.52008
- Product name
- Fmoc-Cys(Trt)-OH
- Purity
- Novabiochem?
- Packaging
- 100g
- Price
- $183
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 8.52008
- Product name
- Fmoc-Cys(Trt)-OH
- Purity
- Novabiochem?
- Packaging
- 250g
- Price
- $365
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 8.52008
- Product name
- Fmoc-Cys(Trt)-OH
- Purity
- Novabiochem?
- Packaging
- 1kg
- Price
- $1370
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 47695
- Product name
- Fmoc-Cys(Trt)-OH
- Purity
- ≥95.0% (sum of enantiomers, HPLC)
- Packaging
- 100g
- Price
- $75.2
- Updated
- 2024/03/01
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FMOC-S-trityl-L-cysteine Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powde
Uses
It is potentially useful for proteomics studies, and solid phase peptide synthesis techniques. Cysteine is versatile amino acid involved with many biological processes, including the formation of disulfide bonds - a critical component of protein structure. This compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function.
Uses
Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative used in peptide synthesis. Some of the examples are:
- Synthesis of mono- and bi-functionalized platinum(IV) complexes to target angiogenic tumor vasculature.
- Synthesis of proteins through native chemical ligation of peptide hydrazides as thioester surrogates via solid-phase synthesis.
- Synthesis of glycoconjugates by conjugating reducing sugars to cysteine residues of peptides.
General Description
The standard derivative for Fmoc SPPS of peptides containing Cys [1]. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation [2,3] to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP?, is to be employed, it is strongly recommended that collidine is used as the base [4], as this has been shown to significantly reduce loss of optical integrity during coupling.
The product number for this product was previously 04-12-1018.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
FMOC-S-trityl-L-cysteine Preparation Products And Raw materials
Raw materials
Preparation Products
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FMOC-S-trityl-L-cysteine Suppliers
- Tel
- --
- Fax
- --
- info@acros.com
- Country
- Belgium
- ProdList
- 6772
- Advantage
- 81
- Tel
- --
- Fax
- --
- Country
- Belgium
- ProdList
- 6293
- Advantage
- 73
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View Lastest Price from FMOC-S-trityl-L-cysteine manufacturers
WUHAN FORTUNA CHEMICAL CO., LTD
- Product
- Fmoc-Cys(Trt)-OH 103213-32-7
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 500kgs
- Release date
- 2021-09-26
Sichuan HongRi Pharma-Tech Co.,Ltd
- Product
- Fmoc-L-Cys(trt)-OH 103213-32-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T
- Release date
- 2023-11-13
hebei hongtan Biotechnology Co., Ltd
- Product
- FMOC-S-trityl-L-cysteine 103213-32-7
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 2000kg
- Release date
- 2024-05-14
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