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FMOC-S-trityl-L-cysteine

Product Name
FMOC-S-trityl-L-cysteine
CAS No.
103213-32-7
Chemical Name
FMOC-S-trityl-L-cysteine
Synonyms
FMOC-CYS(TRT)-OH;FMOC-CYS(TRT);FMOC-L-CYS(TRT)-OH;Fomc-Cys(Trt)-OH;N-FMOC-S-TRITYL-L-CYSTEINE;Fmoc-Cyc(Trt)-OH;FMOC-L-CYS(TRT);Fmoc-Cys(Trt)-0H;FMOC-L-CYS(TRITYL);FMOC Cysteine (trt)
CBNumber
CB2138770
Molecular Formula
C37H31NO4S
Formula Weight
585.71
MOL File
103213-32-7.mol
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FMOC-S-trityl-L-cysteine Property

Melting point:
170-173 °C(lit.)
alpha 
16 º (c=1, THF)
Boiling point:
763.4±60.0 °C(Predicted)
Density 
1.270±0.06 g/cm3(Predicted)
refractive index 
18 ° (C=1, THF)
storage temp. 
2-8°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka
3.70±0.10(Predicted)
form 
Powder
color 
White to almost white
optical activity
[α]20/D +16.0±2°, c = 1% in THF
Water Solubility 
Insoluble in water. Soluble in most organic solvents.
BRN 
4221286
InChIKey
KLBPUVPNPAJWHZ-UMSFTDKQSA-N
CAS DataBase Reference
103213-32-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-26
WGK Germany 
3
F 
9-21
Hazard Note 
Irritant
HS Code 
29309090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.52008
Product name
Fmoc-Cys(Trt)-OH
Purity
Novabiochem?
Packaging
25g
Price
$72.8
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52008
Product name
Fmoc-Cys(Trt)-OH
Purity
Novabiochem?
Packaging
100g
Price
$183
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52008
Product name
Fmoc-Cys(Trt)-OH
Purity
Novabiochem?
Packaging
250g
Price
$365
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52008
Product name
Fmoc-Cys(Trt)-OH
Purity
Novabiochem?
Packaging
1kg
Price
$1370
Updated
2024/03/01
Sigma-Aldrich
Product number
47695
Product name
Fmoc-Cys(Trt)-OH
Purity
≥95.0% (sum of enantiomers, HPLC)
Packaging
100g
Price
$75.2
Updated
2024/03/01
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FMOC-S-trityl-L-cysteine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

It is potentially useful for proteomics studies, and solid phase peptide synthesis techniques. Cysteine is versatile amino acid involved with many biological processes, including the formation of disulfide bonds - a critical component of protein structure. This compound could be useful as an unusual amino acid analog to aid in the deconvolution of protein structure and function.

Uses

Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative used in peptide synthesis. Some of the examples are:

  • Synthesis of mono- and bi-functionalized platinum(IV) complexes to target angiogenic tumor vasculature.
  • Synthesis of proteins through native chemical ligation of peptide hydrazides as thioester surrogates via solid-phase synthesis.
  • Synthesis of glycoconjugates by conjugating reducing sugars to cysteine residues of peptides.

General Description

The standard derivative for Fmoc SPPS of peptides containing Cys [1]. The Trt group is removed with 95% TFA containing 1-5% TIS. Ideally, this derivative should be introduced using the symmetrical anhydride or DIPCDI/HOBt activation [2,3] to minimize enantiomerization. If activation with uronium or phosphonium reagents, such as HBTU or PyBOP?, is to be employed, it is strongly recommended that collidine is used as the base [4], as this has been shown to significantly reduce loss of optical integrity during coupling.

The product number for this product was previously 04-12-1018.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

FMOC-S-trityl-L-cysteine Preparation Products And Raw materials

Raw materials

Preparation Products

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FMOC-S-trityl-L-cysteine Suppliers

Americas 1 Belgium 2 Canada 2 China 352 Europe 6 France 2 Germany 7 Hungary 1 India 15 Italy 2 Japan 9 Poland 1 South Korea 1 Switzerland 7 United Kingdom 18 United States 65 Global 491
Carl Roth offre
Tel
--
Fax
--
Email
r.eckert@rothsochiel.fr
Country
France
ProdList
2361
Advantage
58
NeoMPS SA
Tel
--
Fax
--
Email
neo@neomps.com
Country
France
ProdList
2083
Advantage
71
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View Lastest Price from FMOC-S-trityl-L-cysteine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Fmoc-Cys(Trt)-OH 103213-32-7
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500kgs
Release date
2021-09-26
Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Fmoc-L-Cys(trt)-OH 103213-32-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2023-11-13
hebei hongtan Biotechnology Co., Ltd
Product
FMOC-S-trityl-L-cysteine 103213-32-7
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000kg
Release date
2024-05-14

103213-32-7, FMOC-S-trityl-L-cysteineRelated Search:

ALTRENOGEST METHOXYCARBONYLSULFENYL CHLORIDE Fmoc-Lys(Boc)-OH Triphenylmethyl Chloride Fmoc-Phe-OH p-Toluenesulfonic acid 9-Fluorenylmethyl chloroformate 6-Aminocaproic acid N-(9-Fluorenylmethoxycarbonyloxy)succinimide Glycine L-Fmoc-Aspartic acid alpha-tert-butyl ester PYRAZOPHOS L-Cysteine Trityl candesartan cilexetil Trityl Irbesartan CARBONYL SULFIDE Propionic acid Tris(hydroxymethyl)aminomethane

  • FMOC-CYSTEINE(TRT)-OH
  • FMOC-CYS(TRT)
  • FMOC-CYS(TRT)-OH
  • FMOC-L-CYSTEINE(TRITYL)
  • FMOC-L-CYSTEINE (TRT)
  • FMOC-L-CYS(TRITYL)
  • FMOC-L-CYS(TRT)
  • FMOC-L-CYS(TRT)-OH
  • FMOC-S-TRITYL-L-CYSTEINE
  • 2-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO]-3-(TRITYLTHIO)PROPANOIC ACID
  • L-CYSTEINE-N-FMOC, S-TRITYL
  • 9-FLUORENYLMETHOXYCARBONYL-S-TRITYL-L-CYSTEINE
  • S-TRITYL-L-CYSTEINE, N-FMOC PROTECTED
  • N-ALPHA-FMOC-S-TRITYL-L-CYSTEINE
  • N-(9-FLUORENYL METHOXY CARBONYL)-S-TRITYL-L-CYSTEINE
  • N-9-FLUORENYLMETHYLOXYCARBONYL-S-TRITYL-L-CYSTEINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-S-TRITYL-L-CYSTEINE
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-S-TRITYL-L-CYSTEINE
  • N-FMOC-L-CYS(TRT)-OH
  • N-FMOC-S-TRITYL-L-CYSTEINE
  • (R)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-3-TRITYLSULFANYL-PROPIONIC ACID
  • FMoc-Cys(Trt)-OH FMoc-S-trityl-L-cysteine
  • N-Fmoc-S-trityl-L-cysteine Fmoc-Cys(Trt)-OH
  • (R)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(tritylthio)propanoic acid
  • (R)-(9H-Fluoren-9-yl)methyl (1-hydroxy-3-(tritylthio)propan-2-yl)carbamate
  • Fmoc-Cys(Trt)-OH >=95.0% (sum of enantiomers, HPLC)
  • Fmoc-Cys(Trt)-OH, >=99%
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Cys(Trt)-OH (Cys of Non-Animal Origin)
  • (9H-Fluoren-9-yl)MethOxy]Carbonyl Cys(Trt)-OH (Cys of Animal Origin)
  • Fomc-Cys(Trt)-OH
  • (R)-2-Fmoc-3-tritylsulfanyl-propionic acid
  • Fmoc-S-trityl-L-cysteine≥ 99.7% (HPLC, Chiral purity)
  • Fmoc-Cys(Trt)-OH(Animal origin)
  • Fmoc-Cys(Trt)-OH(Non-Animal origin)
  • (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[(triphenylmethyl)sulfanyl]propanoic acid
  • (2S)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-3-[(triphenylmethyl)thio]propanoate
  • n-(alpha)-fluorenylmethyloxycarbonyl-s-tritylcysteine
  • N<SUB>α</SUB>-Fmoc-S-trityl-L-cysteine
  • N-(9-FLUORENYLMETHOXYCARBONYL)-S-
  • FMOC-CYS(TRT)-OH, 98+%
  • N-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cystei
  • L-Cysteine-3,3-D2-N-FMOC-S-Trityl
  • L-Cysteine-N-FMOC-UL-13C3, 15N, S-Trityl
  • N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-S-(TRIPHENYLMETHYL)-L-CYSTEINE
  • FMOC-S-TRITYL-L-CYSTEINE (FMOC-L-CYS(TRT)-OH)
  • (R)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)cysteine
  • (9-fluorenylmethoxycarbonyl)-L-cysteine (trityl)
  • N-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cysteine, Nα-Fmoc-S-trityl-L-cysteine
  • Nα-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cysteine ,98%
  • N-[(9H-Fluoren-9-yloxy)carbonyl]-S-trityl-L-cysteine
  • FMOC-S-trityl-L-Cysteine,97%
  • Nα-Fmoc-S-trityl-L-c
  • S-Trityl-N-Fomc_L-Cysteine
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-L-cysteine&gt
  • FMOC-CYS(TRT)-OH 25 G
  • FMOC-CYS(TRT)-OH 100 G
  • FMOC-CYS(TRT)-OH 250 G
  • L-Cysteine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-S-(triphenylmethyl)-