2-Trifluoromethylpyrimidine
Uses- Product Name
- 2-Trifluoromethylpyrimidine
- CAS No.
- 116470-67-8
- Chemical Name
- 2-Trifluoromethylpyrimidine
- Synonyms
- 2-Trifluoromethyl pyrimidine;Pyrimidine, 2-(trifluoromethyl)-;Pyrimidine, 2-(trifluoromethyl)- (9CI);2-Trifluoromethylpyrimidine ISO 9001：2015 REACH
- CBNumber
- CB21041048
- Molecular Formula
- C5H3F3N2
- Formula Weight
- 148.09
- MOL File
- 116470-67-8.mol
2-Trifluoromethylpyrimidine Property
- Boiling point:
- 69.0±40.0 °C(Predicted)
- Density
- 1.353±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- -1.90±0.13(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- HCH0143522
- Product name
- 2-TRIFLUOROMETHYLPYRIMIDINE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $376.95
- Updated
- 2021/12/16
- Product number
- Y4912
- Product name
- 2-Trifluoromethyl-pyrimidine
- Packaging
- 1g
- Price
- $443
- Updated
- 2021/12/16
- Product number
- CM132135
- Product name
- 2-(trifluoromethyl)pyrimidine
- Purity
- 97%
- Packaging
- 1g
- Price
- $259
- Updated
- 2021/12/16
- Product number
- CD11343069
- Product name
- 2-(Trifluoromethyl)pyrimidine
- Purity
- 97%
- Packaging
- 1g
- Price
- $274
- Updated
- 2021/12/16
- Product number
- 116470678
- Product name
- 2-(Trifluoromethyl)pyrimidine
- Packaging
- 1g
- Price
- $304.7
- Updated
- 2021/12/16
2-Trifluoromethylpyrimidine Chemical Properties,Usage,Production
Uses
2-Trifluoromethylpyrimidine is an important organic intermediate that is widely used in industries such as printing and dyeing and agriculture.
Synthesis
81290-20-2
4595-60-2
116470-67-8
GENERAL STEPS: AgF (1.27 g, 10 mmol) was dissolved in 10 mL of DMF at room temperature and stirred until fully dissolved, then Me3SiCF3 (1.7 g, 12 mmol) was added. The reaction mixture was stirred continuously for 20 min, followed by the addition of copper powder (1.0 g, 15 mmol). The reaction was continued to be stirred for 4 hours until CuCF3 was completely formed. Next, 2-bromopyrimidine (9 mmol) was added to the reaction system and the reaction mixture was stirred under the conditions listed in Table 1. The progress of the reaction was monitored by 19F NMR spectroscopy until the signal of CuCF3 completely disappeared. Upon completion of the reaction, the mixture was filtered to remove the solid precipitate and the filtrate was poured into 50 mL of water. The organic layer in the aqueous phase was extracted with ether, the organic layers were combined and dried with MgSO4. The ether was removed by evaporation under reduced pressure and the residue was purified by distillation under reduced pressure or crystallization to give the target product 2-trifluoromethylpyrimidine.
References
[1] Journal of Fluorine Chemistry, 2012, vol. 133, p. 67 - 71
2-Trifluoromethylpyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Trifluoromethylpyrimidine manufacturers
- Product
- 2-Trifluoromethylpyrimidine 116470-67-8
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-07
- Product
- 2-Trifluoromethylpyrimidine 116470-67-8
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 97%
- Supply Ability
- 100kg
- Release date
- 2020-01-09