Depemokimab

Product Name: Depemokimab
CAS No.: 2243274-14-6
Chemical Name: Depemokimab
Synonyms: Depemokimab;Depemokimab (anti-IL-5);Research Grade Depemokimab;Research Grade Depemokimab (DHC13603)
CBNumber: CB210617021
Formula Weight: 0
MOL File: Mol file

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Depemokimab Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Depemokimab Chemical Properties,Usage,Production

Uses

Depemokimab (GSK-3511294) is a long-acting anti-IL-15 monoclonal antibody. Depemokimab can be used for research of asthma[1][2].

in vivo

Depemokimab (PK assay in cynomolgus monkeys) shows an approximately 2-fold reduction in clearance compared with Mepolizumab (HY-P9945), and shows an IL-5 binding affinity approximately 30-fold greater than Mepolizumab^[2].

References

[1] Calzetta L, et al. Investigational Treatments in Phase I and II Clinical Trials: A Systematic Review in Asthma. Biomedicines. 2022 Sep 19;10(9):2330. DOI:10.3390/biomedicines10092330
[2] Singh D, et al. A Phase 1 study of the long-acting anti-IL-5 monoclonal antibody GSK3511294 in patients with asthma. Br J Clin Pharmacol. 2022 Feb;88(2):702-712. DOI:10.1111/bcp.15002

Depemokimab Preparation Products And Raw materials

Raw materials

Preparation Products

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Depemokimab Suppliers

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2243274-14-6, DepemokimabRelated Search:

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Depemokimab

Research Grade Depemokimab (DHC13603)

Research Grade Depemokimab

Depemokimab (anti-IL-5)

2243274-14-6