ChemicalBook > CAS DataBase List > Modotuximab
Modotuximab
- Product Name
- Modotuximab
- CAS No.
- 1310460-86-6
- Chemical Name
- Modotuximab
- Synonyms
- Zatuximab;Modotuximab;Modotuximab (anti-EGFR);Research Grade Zatuximab;Research Grade Modotuximab;Research Grade Zatuximab (DHB86910);Research Grade Modotuximab (DHB86904)
- CBNumber
- CB98080870
- Formula Weight
- 0
- MOL File
- Mol file
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Modotuximab Property
- form
- Liquid
- color
- Colorless to light yellow
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Modotuximab Chemical Properties,Usage,Production
Uses
Modotuximab (DS 1024) is an IgG1κ-type chimeric antibody targeting human EGFR protein. Modotuximab binds non-overlapping epitopes on domain III of EGFR, a domain that is intact in EGFRvIII. Modotuximab has antitumor activity in vivo[1].
References
[1] Keir
ST, et al. Sym004-induced EGFR
elimination is associated with profound anti-tumor activity in EGFRvIII
patient-derived glioblastoma models. J Neurooncol. 2018 Jul;138(3):489-498. DOI:10.1007/s11060-018-2832-6
[2] Modotuximab. IMGT Database.
Modotuximab Preparation Products And Raw materials
Raw materials
Preparation Products
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Modotuximab Suppliers
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- 021-61312847; 18021002903
- Fax
- QQ:3008007432
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- China
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- 177-54423994 17754423994
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- China
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- 15817493340
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- China
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- 422450190@qq.com
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- 4008200310
- marketing@tsbiochem.com
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- 027-65279366 18108604356
- products@biolabreagent.com
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- China
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- 13720134139 086-15871494362 13720134139
- orders@jknbiochem.com
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- China
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- 021-65675885 18964387627
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- 17316404525 17316404525
- 209533805@qq.com
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- China
- ProdList
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