WAY-640509

Product Name: WAY-640509
CAS No.: 851185-20-1
Chemical Name: WAY-640509
Synonyms: WAY-640509;WAY 640509,WAY640509
CBNumber: CB211076487
Molecular Formula: C25H23N5O4S
Formula Weight: 489.55
MOL File: 851185-20-1.mol

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Hazard and Precautionary Statements (GHS)

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WAY-640509 Chemical Properties,Usage,Production

Uses

Glucocerebrosidase-IN-2 (compound 12) is a quinazoline analogue and an inhibitor of glucocerebrosidase (GC). Glucocerebrosidase-IN-2 has the potential to improve GC translocation to lysosomes in Gaucher disease patient-derived cells (mostly carrying the N370S mutation). Glucocerebrosidase-IN-2 inhibits the hydrolysis of 4-methylumbelliferone β-D-glucopyranoside (4MU) and fluorescent glycosylceramide (FlourGC) in N370S mutant tissues with an AC50 of 25.29 μM[1].

References

[1] Juan J Marugan, et al. Evaluation of quinazoline analogues as glucocerebrosidase inhibitors with chaperone activity. J Med Chem. 2011, 54, 4. DOI:10.1021/jm1008902

WAY-640509 Preparation Products And Raw materials

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WAY-640509 Suppliers

China 11 United States 2 Global 13

Shanghai YuanYe Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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ShangHai ChuanQian Chemcial Technique Centre

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Xi'an Kaixin Biotechnology Co., Ltd

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TargetMol Chemicals Inc.

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Shanghai Yifei Biotechnology Co. , Ltd.

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Shanghai Aladdin Biochemical Technology Co.,Ltd.

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Sangon Biotech (Shanghai) Co.,Ltd.

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ATK CHEMICAL COMPANY LIMITED

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851185-20-1, WAY-640509Related Search:

2-Furancarboxamide, N-(2-chlorophenyl)-5-[(2-methoxyphenoxy)methyl]- (2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid 2-Furancarboxamide, 5-[[4-(1,1-dimethylethyl)phenoxy]methyl]-N-(2-methoxyphenyl)- Acetic acid, 2-[(5E)-5-[(5-methyl-2-thienyl)methylene]-4-oxo-2-thiazolidinylidene]-, ethyl ester, (2E)- Benzamide, N-[(3-chlorophenyl)methyl]-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]- Propanoic acid, 2-[(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)thio]- N-benzyl-2-[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]acetamide Thiourea, N-(2-fluorophenyl)-N'-[1-(phenylmethyl)-4-piperidinyl]- WAY 361789 2-(4-chloro-2-methylphenoxy)-N-(4,5-dihydro-1,3-thiazol-2-yl)acetamide 1H-Isoindole-1,3(2H)-dione, 2-[3-[4-(2-hydroxyethyl)-1-piperazinyl]-3-oxopropyl]- Benzo[b]thiophene-2-carboxamide, 5-fluoro-N-[3-(4-morpholinylsulfonyl)phenyl]- 5H-Cyclopenta[4,5]thieno[2,3-d]pyrimidine, 6,7-dihydro-4-(1-piperidinyl)- 4-Piperidinecarboxamide, 1-[3-(3,4-dihydro-4-oxo-2-quinazolinyl)-1-oxopropyl]- WAY-600 5-bromo-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide Glycinamide, N-acetylglycyl-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-N2-methyl-2-phenyl- (9CI) Benzamide, 4-(3,5-dimethyl-1H-pyrazol-1-yl)-N-(4-methyl-2-thiazolyl)-

WAY-640509

WAY 640509,WAY640509

851185-20-1