5-bromo-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide
- Product Name
- 5-bromo-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide
- CAS No.
- 515866-67-8
- Chemical Name
- 5-bromo-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide
- Synonyms
- WAY-620147;5-bromo-N-(2-morpholinoethyl)nicotinamide;5-bromo-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide;3-Pyridinecarboxamide, 5-bromo-N-[2-(4-morpholinyl)ethyl]-
- CBNumber
- CB54416394
- Molecular Formula
- C12H16BrN3O2
- Formula Weight
- 314.18
- MOL File
- 515866-67-8.mol
5-bromo-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide Property
- Melting point:
- 107-109 °C
- Boiling point:
- 465.4±45.0 °C(Predicted)
- Density
- 1.426±0.06 g/cm3(Predicted)
- pka
- 13.70±0.46(Predicted)
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
5-bromo-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide Chemical Properties,Usage,Production
Uses
WAY-620147 (compound 6) is an N-(2-morpholinoethyl)nicotinamide derivative that inhibits monoamine oxidase (Monoamine Oxidase). WAY-620147 inhibits MAO-A and MAO-B with IC50s of 26 μM and 55 μM, respectively[1].
References
[1] Shi L, et al. Design of novel nicotinamides as potent and selective monoamine oxidase a inhibitors. Bioorg Med Chem. 2010 Feb 15;18(4):1659-64. DOI:10.1016/j.bmc.2009.12.065
5-bromo-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
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