WAY 361789

Product Name: WAY 361789
CAS No.: 1040718-40-8
Chemical Name: WAY 361789
Synonyms: WAY 361789;WAY 361789,WAY361789;5-(4-acetyl-1,4-diazepan-1-yl)-N-[5-(4-methoxyphenyl)-1H-pyrazol-3-yl]pentanamide
CBNumber: CB32667608
Molecular Formula: C22H31N5O3
Formula Weight: 413.51324
MOL File: 1040718-40-8.mol

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Hazard and Precautionary Statements (GHS)

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WAY 361789 Chemical Properties,Usage,Production

Uses

WAY-361789 (SEN15924) is an orally active agonist for α7 nicotinic acetylcholine receptor (α7 nAChR) with an EC50 of 0.18 μM. WAY-361789 improves the cognitive function, exhibits potential in ameliorating Alzheimer’s Disease and schizophrenia[1].

IC 50

AChE

References

[1] Zanaletti R, et al. Discovery of a novel alpha-7 nicotinic acetylcholine receptor agonist series and characterization of the potent, selective, and orally efficacious agonist 5-(4-acetyl[1,4]diazepan-1-yl)pentanoic acid [5-(4-methoxyphenyl)-1H-pyrazol-3-yl] amide (SEN15924, WAY-361789). J Med Chem. 2012 May 24;55(10):4806-23. DOI:10.1021/jm300247y

WAY 361789 Preparation Products And Raw materials

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Preparation Products

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WAY 361789 Suppliers

China 1 United States 2 Global 3

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TargetMol Chemicals Inc.

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WAY 361789

5-(4-acetyl-1,4-diazepan-1-yl)-N-[5-(4-methoxyphenyl)-1H-pyrazol-3-yl]pentanamide

WAY 361789,WAY361789

1040718-40-8