WAY-640509

Product Name: WAY-640509
CAS No.: 851185-20-1
Chemical Name: WAY-640509
Synonyms: WAY-640509;WAY 640509,WAY640509
CBNumber: CB211076487
Molecular Formula: C25H23N5O4S
Formula Weight: 489.55
MOL File: 851185-20-1.mol

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WAY-640509 Chemical Properties,Usage,Production

Uses

Glucocerebrosidase-IN-2 (compound 12) is a quinazoline analogue and an inhibitor of glucocerebrosidase (GC). Glucocerebrosidase-IN-2 has the potential to improve GC translocation to lysosomes in Gaucher disease patient-derived cells (mostly carrying the N370S mutation). Glucocerebrosidase-IN-2 inhibits the hydrolysis of 4-methylumbelliferone β-D-glucopyranoside (4MU) and fluorescent glycosylceramide (FlourGC) in N370S mutant tissues with an AC50 of 25.29 μM[1].

References

[1] Juan J Marugan, et al. Evaluation of quinazoline analogues as glucocerebrosidase inhibitors with chaperone activity. J Med Chem. 2011, 54, 4. DOI:10.1021/jm1008902

WAY-640509 Preparation Products And Raw materials

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WAY-640509 Suppliers

China 11 United States 2 Global 13

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

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WAY-640509

WAY 640509,WAY640509

851185-20-1