3-(1H-Pyrrol-2-yl)propanoic acid
- Product Name
- 3-(1H-Pyrrol-2-yl)propanoic acid
- CAS No.
- 408309-29-5
- Chemical Name
- 3-(1H-Pyrrol-2-yl)propanoic acid
- Synonyms
- CEP03;CEP-03;CEP 03;1H-Pyrrole-2-propanoic acid;3-(2-Pyrrolyl)propanoic Acid
- CBNumber
- CB21116917
- Molecular Formula
- C7H9NO2
- Formula Weight
- 139.15
- MOL File
- 408309-29-5.mol
3-(1H-Pyrrol-2-yl)propanoic acid Property
- Melting point:
- 85-86 °C
- Boiling point:
- 130-135 °C(Press: 0.5 Torr)
- Density
- 1.245±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 4.51±0.10(Predicted)
- Appearance
- Yellow to brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P840983
- Product name
- 3-(1H-Pyrrol-2-yl)propanoicAcid
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- P840983
- Product name
- 3-(1H-Pyrrol-2-yl)propanoicAcid
- Packaging
- 100mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- 089823
- Product name
- 3-(1H-Pyrrol-2-yl)propanoic acid
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $341
- Updated
- 2021/12/16
- Product number
- X6372
- Product name
- 3-(1H-Pyrrol-2-yl)propanoicacid
- Packaging
- 1g
- Price
- $560
- Updated
- 2021/12/16
- Product number
- 089823
- Product name
- 3-(1H-Pyrrol-2-yl)propanoic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $756
- Updated
- 2021/12/16
3-(1H-Pyrrol-2-yl)propanoic acid Chemical Properties,Usage,Production
Synthesis
55490-37-4
408309-29-5
General procedure for the synthesis of 3-(1H-pyrrol-2-yl)propionic acid from ethyl 3-(1H-pyrrol-2-yl)propionate: sodium hydroxide (3.8 g, 95.00 mmol) was added batchwise to ethyl 3-(1H-pyrrol-2-yl)propionate (8 g, 47.85 mmol) in a mixed solution of ethanol/water (80 mL/40 mL) at 0-5 °C. . The reaction temperature was maintained at 0 °C and the resulting reaction mixture was stirred at room temperature for 5 h. The reaction process was monitored by LCMS. After completion of the reaction, the reaction solution was concentrated under reduced pressure. Subsequently, the pH of the concentrate was adjusted to 3-4 with 10% hydrochloric acid solution and then extracted with ethyl acetate (3 x 100 mL). The organic phases were combined, dried with anhydrous magnesium sulfate and finally concentrated under reduced pressure to give 7 g (95% yield) of 3-(1H-pyrrol-2-yl)propionic acid as a white solid.
References
[1] Patent: WO2009/139834, 2009, A1. Location in patent: Page/Page column 161
[2] European Journal of Organic Chemistry, 2010, # 19, p. 3611 - 3620
[3] Tetrahedron, 2004, vol. 60, # 7, p. 1505 - 1511
3-(1H-Pyrrol-2-yl)propanoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-(1H-Pyrrol-2-yl)propanoic acid Suppliers
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