(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID

Product Name: (-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID
CAS No.: 121083-05-4
Chemical Name: (-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID
Synonyms: L-670,596;L670,596,L 670,596;2-(6,8-Difluoro-9-(4-(methylsulfonyl)benzyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl)acetic acid;(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID
CBNumber: CB3118579
Molecular Formula: C22H21F2NO4S
Formula Weight: 433.47
MOL File: 121083-05-4.mol

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(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID Property

Boiling point:: 693.4±55.0 °C(Predicted)
Density: 1.43±0.1 g/cm3(Predicted)
storage temp.: Store at RT
solubility: Soluble to 100 mM in 1.1eq. NaOH
form: Powder
pka: 4.56±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1949
Product name: L-670,596
Purity: ≥98%(HPLC)
Packaging: 10
Price: $144
Updated: 2021/12/16

TRC

Product number: L676020
Product name: L-670,596
Packaging: 2.5mg
Price: $275
Updated: 2021/12/16

Usbiological

Product number: 453155
Product name: L-670,596
Packaging: 1mg
Price: $410
Updated: 2021/12/16

Usbiological

Product number: 255636
Product name: L-670,596
Packaging: 10mg
Price: $466
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0135731
Product name: (-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID
Purity: 95.00%
Packaging: 1G
Price: $1004.85
Updated: 2021/12/16

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(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID Chemical Properties,Usage,Production

Uses

L-670,596 is a potent and selective thromboxane/prostaglandin endoperoxide receptor antagonist.

Definition

ChEBI: 2-[6,8-difluoro-9-[(4-methylsulfonylphenyl)methyl]-1,2,3,4-tetrahydrocarbazol-1-yl]acetic acid is a member of carbazoles.

Biological Activity

Potent and selective thromboxane A 2 /prostaglandin endoperoxide receptor antagonist (IC 50 = 5.5 nM). Inhibits U-44069-induced contractions of guinea pig trachea (pA 2 = 9.0) and human platelet aggregation in vitro (IC 50 = 6.5 nM). Also prevents thromboxane-mediated endothelial cell death. Orally active in vivo .

(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID Suppliers

China 4 Europe 1 Germany 3 South Korea 1 United Kingdom 2 United States 7 USA 1 Global 19

3B Pharmachem (Wuhan) International Co.,Ltd.

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121083-05-4, (-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACIDRelated Search:

N-BENZYL-1,2,3,4-TETRAHYDROCARBAZOLE 7-Fluoroindole 5,7-Difluoroindole 4-METHYLSULFONYLBENZYLAMINE HYDROCHLORIDE 5-Fluoro-2-methylindole 6-(1H-INDOL-3-YL)HEXANOIC ACID 3-(1H-Pyrrol-2-yl)propanoic acid 5-Fluoro-2,3-dimethyl-1H-indole (-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID

L-670,596

(-)-6-8-DIFLUORO-2,3,4,9-TETRAHYDRO-9-[[4-(METHYLSULFONYL)PHENYL]METHYL]-1H-CARBAZOLE-1-ACETIC ACID

2-(6,8-Difluoro-9-(4-(methylsulfonyl)benzyl)-2,3,4,9-tetrahydro-1H-carbazol-1-yl)acetic acid

L670,596,L 670,596

121083-05-4

C22H21F2NO4S

Prostanoid receptor and related