5-Fluoro-2-methylindole
- Product Name
- 5-Fluoro-2-methylindole
- CAS No.
- 399-72-4
- Chemical Name
- 5-Fluoro-2-methylindole
- Synonyms
- 5-FLUORO-2-METHYL-1H-INDOLE;5-FLUORO-2-METHYLINDOLE;1H-Indole, 5-fluoro-2-methyl-;5-Fluoro-2-methyl-1H-indole 97%
- CBNumber
- CB3294509
- Molecular Formula
- C9H8FN
- Formula Weight
- 149.16
- MOL File
- 399-72-4.mol
5-Fluoro-2-methylindole Property
- Melting point:
- 98-101 °C (lit.)
- Boiling point:
- 112-120C
- Density
- 1.219±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- Solid
- pka
- 16.73±0.30(Predicted)
- color
- Light yellow to Brown
- InChI
- InChI=1S/C9H8FN/c1-6-4-7-5-8(10)2-3-9(7)11-6/h2-5,11H,1H3
- InChIKey
- JJIUISYYTFDATN-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=C(F)C=C2)C=C1C
- CAS DataBase Reference
- 399-72-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,T
- Risk Statements
- 36/37/38-25
- Safety Statements
- 26-36-45-36/37/39
- WGK Germany
- 3
- Hazard Note
- Irritant
- HS Code
- 2933998090
- Storage Class
- 11 - Combustible Solids
- Hazard Classifications
- Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- F1047
- Product name
- 5-Fluoro-2-methylindole
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $137
- Updated
- 2026/03/19
- Product number
- F1047
- Product name
- 5-Fluoro-2-methylindole
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $430
- Updated
- 2026/03/19
- Product number
- F597078
- Product name
- 5-Fluoro-2-methylindole
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- F597078
- Product name
- 5-Fluoro-2-methylindole
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 3H31-3-52
- Product name
- 5-Fluoro-2-methylindole
- Purity
- 97%
- Packaging
- 5G
- Price
- $50
- Updated
- 2021/12/16
5-Fluoro-2-methylindole Chemical Properties,Usage,Production
Description
5-Fluoro-2-methylindole is a chemical intermediate that can be used in the synthesis of other compounds. It is a versatile building block with many applications, such as being a useful intermediate for the synthesis of heterocyclic compounds. This compound reacts with aniline to form 2,6-diaminopyridine, which has been shown to have anti-inflammatory properties.
General Description
5-Fluoro-2-methylindole (5-Fluoro-2-methyl-1H-indole) is a 5-substituted-2-methyl-1H-indole.
Synthesis
1-(5-fluoro-2-nitrophenyl) propane-2-one (0.5mmol, 99 mg), zinc powder (3.0mmol, 196 mg), and acetic acid (6.0mmol, 360 mg) was added to the reaction tube, followed by adding ethanol to 2 ml at 90 °C for 3h. After cooling to room temperature, the reaction system was added 20 ml water. 5-Fluoro-2-methylindole was obtained after purification.
Solubility in water
Very soluble in N,N-Dimethylformamide,Soluble in methanol,Sparingly soluble inglacial acetic acid, Very slightly soluble inchloroform, Practically insoluble in water.
References
[1] Organic and Biomolecular Chemistry, 2016, vol. 14, # 44, p. 10511 - 10515
[2] Patent: CN106631968, 2017, A. Location in patent: Paragraph 0069-0072; 0074
5-Fluoro-2-methylindole Preparation Products And Raw materials
Raw materials
Preparation Products
5-Fluoro-2-methylindole Suppliers
- Tel
- 18028661570
- 2412659056@qq.com
- Country
- China
- ProdList
- 291
- Advantage
- 58
- Tel
- +86-0519-85485169 +86-13961161173
- sales@kangruipharm.com
- Country
- China
- ProdList
- 262
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 400-021-7337 2355568890
- Fax
- 0086-21-50182339
- sales@demochem.com
- Country
- China
- ProdList
- 2572
- Advantage
- 57
- Tel
- 847-367-3680
- Fax
- 847-367-3681
- sales@arkpharminc.com
- Country
- United States
- ProdList
- 1670
- Advantage
- 56
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44802
- Advantage
- 61
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9254
- Advantage
- 66
View Lastest Price from 5-Fluoro-2-methylindole manufacturers
- Product
- 5-Fluoro-2-methylindole 399-72-4
- Price
- US $1000.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100kg
- Release date
- 2018-08-03