Hopantenic

Product Name: Hopantenic
CAS No.: 18679-90-8
Chemical Name: Hopantenic
Synonyms: HOPA;Hopantenic;Homopantothenic acid;D-Homopantothenic acid;Dexpanthenol iMpurity I;D-(+)-Homopantothenic acid;Ethyl Acetate Impurity 2 (Ethyl Acetate EP Impurity B);(R)-4-(2,4-Dihydroxy-3,3-dimethylbutanamido)butanoic acid;4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoicaci;4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid
CBNumber: CB21178904
Molecular Formula: C10H19NO5
Formula Weight: 233.26
MOL File: 18679-90-8.mol

More

Less

Hopantenic Property

Melting point:: 62-64 °C
Boiling point:: 556.0±50.0 °C(Predicted)
alpha: D20 +23.8°
Density: 1.230±0.06 g/cm3(Predicted)
pka: 4.52 at 25°
form: Oil
color: Colorless to light yellow

More

Less

Safety

HazardClass: IRRITANT
Toxicity: LD50 in male, female mice, male, female rats (mg/kg): 850, 954, 1575, 1458 i.p.; 2063, 2495, 5940, 7348 s.c.; 6297, 7935, 16810, 13350 orally (Nishizawa)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Matrix Scientific

Product number: 059739
Product name: 4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid
Packaging: 500mg
Price: $199
Updated: 2021/12/16

Aronis compounds

Product number: BBC/454
Product name: 4-[(2,4-dihydroxy-3,3-dimethylbutanoyl)amino]butanoicacid
Packaging: 1g
Price: $195
Updated: 2021/12/16

Crysdot

Product number: CD13019633
Product name: (R)-4-(2,4-Dihydroxy-3,3-dimethylbutanamido)butanoicacid
Purity: 95+%
Packaging: 5g
Price: $627
Updated: 2021/12/16

More

Less

Hopantenic Chemical Properties,Usage,Production

Uses

HoPan inhibits phosphopantotenoylcysteine synthetase activity.

Definition

ChEBI: Hopantenic acid is an organooxygen compound and an organonitrogen compound. It is functionally related to a gamma-amino acid.

References

[1] Mostert KJ, et al. The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity. ACS Chem Biol. 2021 Nov 19;16(11):2401-2414. DOI:10.1021/acschembio.1c00535

Hopantenic Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Hopantenic Suppliers

China 24 India 2 Russia 1 United States 3 Global 30

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15873
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

Shanghai Synchem Pharma Co., ltd

Tel: 21-619849051-1 18521059765
Email: synchempharma@aliyun.com
Country: China
ProdList: 6468
Advantage: 55

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

Guangdong Wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886766 13927870850
Fax: 0751-2886756
Email: 3001267247@qq.com
Country: China
ProdList: 9941
Advantage: 58

Cato Research Chemicals Inc.

Tel: +86-020-81960175-877 4000-868-328
Email: tianwen.zhan@cato-chem.com
Country: United States
ProdList: 10404
Advantage: 58

Wuxi Minglu Medicine technology Co.,Ltd.

Tel: 0510-88726693
Fax: 0510-88726693
Email: 3204601684@qq.com
Country: China
ProdList: 2215
Advantage: 58

18679-90-8, HopantenicRelated Search:

DIHYDRO-4,4-DIMETHYL-2,3-FURANDIONE Panthenol Dexpanthenol Dexpanthenol iMpurity F hopantenic acid L-Panthenol Hopantenic CALCIUM D-(+)-4-(2,4-DIHYDROXY-3,3-DIMETHYLBUTYLAMIDO)BUTYRATE HEMIHYDRATE

Dexpanthenol iMpurity I

Hopantenic

Butanoic acid, 4-[(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino]-, (R)-

Butanoic acid, 4-[[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]amino]-

Butyric acid, 4-(2,4-dihydroxy-3,3-dimethylbutyramido)-, D-(+)- (8CI)

D-(+)-Homopantothenic acid

D-Homopantothenic acid

Homopantothenic acid

(+)-4-[[(R)-2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl]amino]butyric acid

4-[[(2R)-2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl]amino]butanoic acid

HOPA

4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid

(R)-4-(2,4-Dihydroxy-3,3-dimethylbutanamido)butanoic acid

4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoicaci

Ethyl Acetate Impurity 2 (Ethyl Acetate EP Impurity B)

18679-90-8