Hopantenic

Product Name: Hopantenic
CAS No.: 18679-90-8
Chemical Name: Hopantenic
Synonyms: HOPA;Hopantenic;Homopantothenic acid;D-Homopantothenic acid;Dexpanthenol iMpurity I;D-(+)-Homopantothenic acid;Ethyl Acetate Impurity 2 (Ethyl Acetate EP Impurity B);(R)-4-(2,4-Dihydroxy-3,3-dimethylbutanamido)butanoic acid;4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoicaci;4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid
CBNumber: CB21178904
Molecular Formula: C10H19NO5
Formula Weight: 233.26
MOL File: 18679-90-8.mol

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Hopantenic Property

Melting point:: 62-64 °C
Boiling point:: 556.0±50.0 °C(Predicted)
alpha: D20 +23.8°
Density: 1.230±0.06 g/cm3(Predicted)
pka: 4.52 at 25°
form: Oil
color: Colorless to light yellow

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Safety

HazardClass: IRRITANT
Toxicity: LD50 in male, female mice, male, female rats (mg/kg): 850, 954, 1575, 1458 i.p.; 2063, 2495, 5940, 7348 s.c.; 6297, 7935, 16810, 13350 orally (Nishizawa)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 059739
Product name: 4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid
Packaging: 500mg
Price: $199
Updated: 2021/12/16

Crysdot

Product number: CD13019633
Product name: (R)-4-(2,4-Dihydroxy-3,3-dimethylbutanamido)butanoicacid
Purity: 95+%
Packaging: 5g
Price: $627
Updated: 2021/12/16

Aronis compounds

Product number: BBC/454
Product name: 4-[(2,4-dihydroxy-3,3-dimethylbutanoyl)amino]butanoicacid
Packaging: 1g
Price: $195
Updated: 2021/12/16

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Hopantenic Chemical Properties,Usage,Production

Uses

HoPan inhibits phosphopantotenoylcysteine synthetase activity.

Definition

ChEBI: Hopantenic acid is an organooxygen compound and an organonitrogen compound. It is functionally related to a gamma-amino acid.

References

[1] Mostert KJ, et al. The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity. ACS Chem Biol. 2021 Nov 19;16(11):2401-2414. DOI:10.1021/acschembio.1c00535

Hopantenic Preparation Products And Raw materials

Raw materials

Preparation Products

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Hopantenic Suppliers

China 24 India 2 Russia 1 United States 3 Global 30

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18679-90-8, HopantenicRelated Search:

DIHYDRO-4,4-DIMETHYL-2,3-FURANDIONE Panthenol Dexpanthenol Dexpanthenol iMpurity F hopantenic acid L-Panthenol Hopantenic CALCIUM D-(+)-4-(2,4-DIHYDROXY-3,3-DIMETHYLBUTYLAMIDO)BUTYRATE HEMIHYDRATE

Dexpanthenol iMpurity I

Hopantenic

Butanoic acid, 4-[(2,4-dihydroxy-3,3-dimethyl-1-oxobutyl)amino]-, (R)-

Butanoic acid, 4-[[(2R)-2,4-dihydroxy-3,3-dimethyl-1-oxobutyl]amino]-

Butyric acid, 4-(2,4-dihydroxy-3,3-dimethylbutyramido)-, D-(+)- (8CI)

D-(+)-Homopantothenic acid

D-Homopantothenic acid

Homopantothenic acid

(+)-4-[[(R)-2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl]amino]butyric acid

4-[[(2R)-2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl]amino]butanoic acid

HOPA

4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoic acid

(R)-4-(2,4-Dihydroxy-3,3-dimethylbutanamido)butanoic acid

4-[(2,4-Dihydroxy-3,3-dimethylbutanoyl)amino]-butanoicaci

Ethyl Acetate Impurity 2 (Ethyl Acetate EP Impurity B)

18679-90-8