Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)-

Product Name: Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)-
CAS No.: 333357-56-5
Chemical Name: Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)-
Synonyms: WAY-299838;HIF-1 inhibitor-4;HIF-1 inhibitor-4, 10 mM in DMSO;N-(4-Iodophenyl)-4-(morpholinomethyl)benzamide;Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)-
CBNumber: CB212123692
Molecular Formula: C18H19IN2O2
Formula Weight: 422.26
MOL File: 333357-56-5.mol

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Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)- Property

Boiling point:: 435.4±45.0 °C(Predicted)
Density: 1.576±0.06 g/cm3(Predicted)
pka: 12.90±0.70(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)- Chemical Properties,Usage,Production

Uses

HIF-1 inhibitor-4 is a HIF-1 inhibitor (IC50: 560 nM). HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level[1].

References

[1] Nagao S, et al. Synthesis and structure-activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors. Bioorg Med Chem. 2014 Oct 1;22(19):5513-29. DOI:10.1016/j.bmc.2014.07.020

Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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333357-56-5, Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)-Related Search:

2H-Indol-2-one, 1,3-dihydro-3-[(5-methyl-2-furanyl)methylene]- N-[2-[4-(2-METHOXYPHENYL)-1-PIPERAZINYL]ETHYL]-N-2-PYRIDINYL-CYCLOHEXANECARBOXAMIDE MALEATE 1-(1,3-benzodioxol-5-ylmethyl)-4-[(3,4-dimethoxyphenyl)sulfonyl]piperazine N-(4-chlorophenyl)-2-(thiophen-2-yl)acetamide (4-benzylpiperidin-1-yl)(4-fluorophenyl)methanone Ethanone, 1-(4-bromophenyl)-2-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]- 3-(3,5-dimethyl-1H-pyrazol-1-yl)-N-(4-methylphenyl)propanamide 5-(3-bromophenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione N-(6-bromobenzo[d]thiazol-2-yl)cyclohexanecarboxamide 1-(4-fluorobenzoyl)-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine Benzamide, N-methyl-4-phenoxy-N-(phenylmethyl)- Benzenesulfonamide, N,N'-1,2-ethanediylbis[3-methyl- Acetamide, N-1H-benzimidazol-2-yl-2-phenoxy- 3-chloro-4-morpholin-4-yl-1-phenylpyrrole-2,5-dione WAY-234759 2-(1,3-benzoxazol-2-ylsulfanyl)-N-phenylacetamide 2-benzylsulfanyl-5-(4-methylphenyl)-1,3,4-oxadiazole 2H-1,4-Benzoxazin-3(4H)-one, 6-[2-[(1,6-dihydro-4-methyl-6-oxo-2-pyrimidinyl)thio]acetyl]-

Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)-

WAY-299838

N-(4-Iodophenyl)-4-(morpholinomethyl)benzamide

HIF-1 inhibitor-4

HIF-1 inhibitor-4, 10 mM in DMSO

333357-56-5