H-LEU-SER-LYS-LEU-NH2

Product Name: H-LEU-SER-LYS-LEU-NH2
CAS No.: 283609-79-0
Chemical Name: H-LEU-SER-LYS-LEU-NH2
Synonyms: LSKL;LSKL(a);LSKL-NH2;LSKL, BR;LEU-SER-LYS-LEU-NH2;H-LEU-SER-LYS-LEU-NH2;H-Leu-Ser-Lys-Leu-NH?;Leu-Ser-Lys-Leu peptide;INHIBITOR OF THROMBOSPONDIN (TSP-1);L-Leucinamide, L-leucyl-L-seryl-L-lysyl-
CBNumber: CB2125574
Molecular Formula: C21H42N6O5
Formula Weight: 458.6
MOL File: Mol file

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H-LEU-SER-LYS-LEU-NH2 Property

Boiling point:: 817.8±65.0 °C(Predicted)
Density: 1.143±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO : ≥ 100 mg/mL (218.05 mM)
pka: 13.40±0.46(Predicted)
form: Solid
color: White to off-white
Sequence: H-Leu-Ser-Lys-Leu-NH2

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-7048
Product name: LSKL,InhibitorofThrombospondinTSP-1
Packaging: 5mg
Price: $108
Updated: 2021/12/16

ChemScene

Product number: CS-7048
Product name: LSKL,InhibitorofThrombospondinTSP-1
Packaging: 10mg
Price: $156
Updated: 2021/12/16

ChemScene

Product number: CS-7048
Product name: LSKL,InhibitorofThrombospondinTSP-1
Packaging: 25mg
Price: $312
Updated: 2021/12/16

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H-LEU-SER-LYS-LEU-NH2 Chemical Properties,Usage,Production

Uses

L-Leucyl-L-seryl-L-lysyl-L-leucinamide can be useful in the study of relative contributions of core protein and solvation shell in terahertz dielectric properties of protein solutions.

in vivo

LSKL, Inhibitor of Thrombospondin (TSP-1) (1 mg/kg; intraperitoneal injection; male Sprague-Dawley rats) is protective against subarachnoid fibrosis, attenuates ventriculomegaly and effectively suppresses hydrocephalus. LSKL, Inhibitor of Thrombospondin (TSP-1) treatment inhibits TGF-β1 activity and subsequent Smad2/3 signaling^[1].
LSKL, Inhibitor of Thrombospondin (TSP-1) (30 mg/kg, i.p.) successfully inhibits transforming growth factor (TGF) β-Smad signal activation induced by partial hepatectomy. LSKL, Inhibitor of Thrombospondin (TSP-1) successfully attenuates TGF-β-Smad signal activation by antagonizing TSP-1, but not by reducing TSP-1 protein expression. LSKL, Inhibitor of Thrombospondin (TSP-1) accelerates hepatocyte proliferation after hepatectomy^[3].

Animal Model:	103 male Sprague-Dawley rats (6 weeks of age; 160-180 g) with subarachnoid hemorrhage (SAH)^[1]
Dosage:	1 mg/kg
Administration:	Intraperitoneal injection
Result:	Was protective against subarachnoid fibrosis, attenuated ventriculomegaly and effectively suppressed hydrocephalus.

H-LEU-SER-LYS-LEU-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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H-LEU-SER-LYS-LEU-NH2 Suppliers

China 61 Switzerland 1 United States 8 Global 70

GL Biochem (Shanghai) Ltd

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Nanjing Peptide Biotech Ltd.

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283609-79-0, H-LEU-SER-LYS-LEU-NH2Related Search:

H-GLY-GLY-SER-LEU-TYR-SER-PHE-GLY-LEU-NH2 ALLATOSTATIN IV RGDV AUTOCAMTIDE-2-RELATED INHIBITORY PEPTIDE Z-Ile-Glu-Pro-Phe-OMe ATRIAL NATRIURETIC FACTOR (1-28) (RAT) H-GLY-ASP-GLY-ARG-LEU-TYR-ALA-PHE-GLY-LEU-NH2 ALLATOSTATIN I RIP H-LEU-SER-ALA-LEU-OH H-LEU-SER-LYS-LEU-OH H-VAL-PRO-PRO-OH PEP2M Histatin 5 Aprotinin (D-ALA1)-PEPTIDE T AMIDE CYCLO(-ARG-GLY-ASP-D-TYR-LYS)

INHIBITOR OF THROMBOSPONDIN (TSP-1)

LEU-SER-LYS-LEU-NH2

H-LEU-SER-LYS-LEU-NH2

LSKL

LSKL-NH2

Leu-Ser-Lys-Leu peptide

LSKL, BR

H-Leu-Ser-Lys-Leu-NH?

LSKL(a)

L-Leucinamide, L-leucyl-L-seryl-L-lysyl-

(S)-6-amino-N-((S)-1-amino-4-methyl-1-oxopentan-2-yl)-2-((S)-2-((S)-2-amino-4-methylpentanamido)-3-hydroxypropanamido)hexanamide

H-Leu-Ser-Lys-Leu-NH2 trifluoroacetate salt

Thrombospondin (TSP-1) Inhibitor, LSKL - 1 mg

Thrombospondin (TSP-1) Inhibitor scrambled peptide, SLLK - 1 mg

283609-79-0

C21H42N6O5

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