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CYCLO(-ARG-GLY-ASP-D-TYR-LYS)

Product Name
CYCLO(-ARG-GLY-ASP-D-TYR-LYS)
CAS No.
217099-14-4
Chemical Name
CYCLO(-ARG-GLY-ASP-D-TYR-LYS)
Synonyms
CYCLO(-RGDYK);Cyclo (-RGDyK) - 5 mg;c(RGDyK),Cyclo(RGDyK);cyclo (Arg-Gly-Asp-Tyr-Lys);CYCLO(-ARG-GLY-ASP-D-TYR-LYS);Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) trifluoroacetate salt;Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl);2-((2S,5R,8S,11S)-8-(4-Aminobutyl)-11-(3-guanidinopropyl)-5-(4-hydroxybenzyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid
CBNumber
CB8205029
Molecular Formula
C27H41N9O8
Formula Weight
619.68
MOL File
217099-14-4.mol
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CYCLO(-ARG-GLY-ASP-D-TYR-LYS) Property

Density 
1.52±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
4.01±0.10(Predicted)
form 
Solid
color 
White to off-white
Sequence
Cyclo(Arg-Gly-Asp-{d-Tyr}-Lys)
InChIKey
LAROZEWEPNAWMD-OFICADHYNA-N
SMILES
C(C1C=CC(=CC=1)O)[C@H]1NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC1=O)CCCCN)=O)CCCNC(N)=N)=O)=O)CC(=O)O)=O |&1:8,11,17,20,r|
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

aablocks
Product number
AA01E72G
Product name
Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl)
Purity
98%
Packaging
50mg
Price
$96
Updated
2026/05/30
aablocks
Product number
AA01E72G
Product name
Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl)
Purity
98%
Packaging
100mg
Price
$159
Updated
2026/05/30
aablocks
Product number
AA01E72G
Product name
Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl)
Purity
98%
Packaging
250mg
Price
$268
Updated
2026/05/30
Biosynth
Product number
FC110223
Product name
Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) trifluoroacetate salt
Packaging
5mg
Price
$320
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0001192
Product name
CYCLO(-RGDYK)
Purity
95.00%
Packaging
1MG
Price
$618.5
Updated
2021/12/16
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CYCLO(-ARG-GLY-ASP-D-TYR-LYS) Chemical Properties,Usage,Production

Uses

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.

IC 50

αvβ3: 20 nM (IC50)

References

[1] Haubner R, et al. Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001 Feb;42(2):326-36. PMID:11216533

CYCLO(-ARG-GLY-ASP-D-TYR-LYS) Preparation Products And Raw materials

Raw materials

Preparation Products

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CYCLO(-ARG-GLY-ASP-D-TYR-LYS) Suppliers

Shanghai HongTide Biotechnology Co.,Ltd.
Tel
15318089928
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China
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13758194781
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China
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GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
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86-21-61263399
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China
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Bide Pharmatech Ltd.
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+86-21-61629029
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
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Creative Peptides
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United States
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Shanghai YuanYe Biotechnology Co., Ltd.
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Alabiotech Inc.
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Nanjing Leon Biological Technology Co., Ltd.
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Nanjing Peptide Biotech Ltd.
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217099-14-4, CYCLO(-ARG-GLY-ASP-D-TYR-LYS)Related Search:


  • CYCLO(-ARG-GLY-ASP-D-TYR-LYS)
  • CYCLO(-RGDYK)
  • cyclo (Arg-Gly-Asp-Tyr-Lys)
  • Cyclo(-Arg-Gly-Asp-D-Tyr-Lys) trifluoroacetate salt
  • Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl)
  • c(RGDyK),Cyclo(RGDyK)
  • 2-((2S,5R,8S,11S)-8-(4-Aminobutyl)-11-(3-guanidinopropyl)-5-(4-hydroxybenzyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid
  • Cyclo (-RGDyK) - 5 mg
  • 217099-14-4
  • peptide