2-Pyridinecarbonitrile,5-formyl-(9CI)

Product Name: 2-Pyridinecarbonitrile,5-formyl-(9CI)
CAS No.: 131747-68-7
Chemical Name: 2-Pyridinecarbonitrile,5-formyl-(9CI)
Synonyms: 5-ForMylpicolinonitrile;5-forMylpyridin-2-carbonitrile;5-ForMyl-2-pyridinecarbonitrile;5-formylpyridine-2-carbonitrile;6-Cyanopyridine-3-carboxaldehyde;2-cyanopyridine-5-carboxyaldehyde;5-formylpyridine-2-carboxonitrile;2-Pyridinecarbonitrile, 5-formyl-;5-ForMyl-2-pyridinecarbonitrile, 95+%;2-Pyridinecarbonitrile,5-formyl-(9CI)
CBNumber: CB21276585
Molecular Formula: C7H4N2O
Formula Weight: 132.12
MOL File: 131747-68-7.mol

More

Less

2-Pyridinecarbonitrile,5-formyl-(9CI) Property

Melting point:: 86-88°C
Boiling point:: 331.3±27.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Chloroform, Methanol
form: Solid
pka: -2.12±0.10(Predicted)
color: Off-White to Pale Yellow

More

Less

Safety

HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

More

Less

N-Bromosuccinimide Price

TRC

Product number: C982195
Product name: 6-Cyanopyridine-3-carboxaldehyde
Packaging: 10g
Price: $1135
Updated: 2021/12/16

AK Scientific

Product number: J97048
Product name: 5-Formyl-2-pyridinecarbonitrile
Packaging: 250mg
Price: $90
Updated: 2021/12/16

Apolloscientific

Product number: OR300168
Product name: 5-Formylpyridine-2-carbonitrile
Packaging: 1g
Price: $138
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H37-1-2D
Product name: 5-Formylpyridine-2-carbonitrile
Packaging: 1g
Price: $152
Updated: 2021/12/16

Matrix Scientific

Product number: 075755
Product name: 5-Formyl-2-pyridinecarbonitrile
Purity: 95+%
Packaging: 500mg
Price: $200
Updated: 2021/12/16

More

Less

2-Pyridinecarbonitrile,5-formyl-(9CI) Chemical Properties,Usage,Production

Uses

6-Cyanopyridine-3-carboxaldehyde, is an intermediate used for the synthesis of pharmaceutical compounds, such as GLPG0634 (C982190), which is used for treatment of rheumatoid arthritis

Synthesis

671776-91-3

131747-68-7

Under nitrogen protection, 5-(1,3-dioxolan-2-yl)pyridine-2-carbonitrile (478 mg, 2.71 mmol) was dissolved in THF (5.0 mL) followed by addition of 1 mol/L hydrochloric acid (5.0 mL). The reaction mixture was stirred at room temperature for 16 hours and then continued at 50 °C for 13 hours. Upon completion of the reaction, the reaction mixture was neutralized with saturated aqueous sodium bicarbonate. The product was extracted with ethyl acetate and the organic phase was washed with saturated brine and dried with anhydrous sodium sulfate. After filtration, the filtrate was concentrated under reduced pressure to give 5-formylpyridine-2-carbonitrile (364 mg, 100% yield).

References

[1] Patent: US2013/65905, 2013, A1. Location in patent: Paragraph 0182
[2] Patent: WO2004/24700, 2004, A1. Location in patent: Page 35

2-Pyridinecarbonitrile,5-formyl-(9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-Pyridinecarbonitrile,5-formyl-(9CI) Suppliers

China 85 Europe 1 India 2 United Kingdom 1 United States 5 Global 94

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

Shanghai Synthfine Chemical Co.,Ltd

Tel: 15921303235
Fax: QQ489466966
Email: sales@synthfine.com
Country: China
ProdList: 1043
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

Shanghai Witofly Chemical Co.,Ltd

Tel
Email: sales@witofly.com
Country: China
ProdList: 2864
Advantage: 52

Shanghai Raise Chemical Technology Co.,Ltd

Tel: 15026594951
Fax: 0556-5030632
Email: rs@raise-chem.com
Country: China
ProdList: 4454
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

131747-68-7, 2-Pyridinecarbonitrile,5-formyl-(9CI)Related Search:

5-FORNYL-3-PYRIDINECARBONITRILE METHYL 5-FORMYLNICOTINATE ETHYL 5-FORMYL-1H-PYRROLE-2-CARBOXYLATE 5-FORMYLURACIL

2-Pyridinecarbonitrile,5-formyl-(9CI)

2-cyanopyridine-5-carboxyaldehyde

5-formylpyridine-2-carbonitrile

5-ForMylpicolinonitrile

5-ForMyl-2-pyridinecarbonitrile

5-forMylpyridin-2-carbonitrile

6-Cyanopyridine-3-carboxaldehyde

5-ForMyl-2-pyridinecarbonitrile, 95+%

2-Pyridinecarbonitrile, 5-formyl-

5-formylpyridine-2-carboxonitrile

131747-68-7

Heterocycle-Pyridine series

PYRIDINE