1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI)

Application

Product Name: 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI)
CAS No.: 199336-83-9
Chemical Name: 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI)
Synonyms: tert-butyl (R)-3-(methylamino)pyrrolidine-1-carboxylate;1-N-Boc-3-(R)-(Methylamino) pyrrolidine;(R)-1-Boc-3-(methylamino)pyrrolidine HCl;(R)-1-Boc-3-(Methylamino)pyrrolidinehydrochloride;(S)-1-Boc-3-methylaminopyrrolidine, hydrochloride;2-Methyl-2-propanyl methyl(3-pyrrolidinyl)carbamate;(R)-benzyl 3-(methylamino)pyrrolidine-1-carboxylate;ert-butyl(3R)-3-(methylamino)pyrrolidine-1-carboxylate;tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate;1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethyleth...
CBNumber: CB21281008
Molecular Formula: C10H20N2O2
Formula Weight: 200.28
MOL File: 199336-83-9.mol

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1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) Property

Boiling point:: 269 ºC
Density: 1.03
Flash point:: 117 ºC
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 10.02±0.20(Predicted)
Appearance: Colorless to light yellow Liquid

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Safety

RIDADR: UN2735
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

SynQuest Laboratories

Product number: 4H56-1-LW
Product name: (R)-1-Boc-3-(methylamino)pyrrolidine
Packaging: 250mg
Price: $43
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB143150
Product name: (R)-tert-Butyl 3-(methylamino)pyrrolidine-1-carboxylate
Packaging: 500mg
Price: $50
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-1-LW
Product name: (R)-1-Boc-3-(methylamino)pyrrolidine
Packaging: 1g
Price: $134
Updated: 2021/12/16

Activate Scientific

Product number: AS22757
Product name: (R)-1-Boc-3-(methylamino)pyrrolidine
Purity: 97% ee
Packaging: 1g
Price: $137
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB143150
Product name: (R)-tert-Butyl 3-(methylamino)pyrrolidine-1-carboxylate
Packaging: 2g
Price: $153
Updated: 2021/12/16

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1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) Chemical Properties,Usage,Production

Application

(R)-3-(methylamino)pyrrolidine-1-carboxylic acid tert-butyl ester can be used as an organic synthesis intermediate and a pharmaceutical intermediate, mainly in laboratory research and development processes and chemical production processes.

Synthesis

1004538-35-5

199336-83-9

Step 7-2: 1.18 g of (R)-1-(tert-butoxycarbonyl)-3-methylaminopyrrolidine hydrochloride (chemical purity: 99.9 area%) was mixed with 2.30 g of 23 wt. % brine, 4.71 g of toluene and 734 mg of 30 wt. % aqueous sodium hydroxide solution, and was prepared in accordance with the methodology described in Step 7-1. After stirring the reaction mixture, a partitioning operation was carried out. The organic layer was concentrated and dried under vacuum to give 946 mg of tert-butyl (R)-3-(methylamino)pyrrolidine-1-carboxylate as a colorless, transparent liquid (chemical purity: 99.3 area%, yield 97%).1H-NMR (CDCl3) data: δ (ppm) 1.45 (s, 9H), 1.71 (m, 2H), 2.04 (m, 1H). 2.44 (s, 3H), 3.03-3.28 (m, 2H), 3.29-3.65 (m, 3H).

References

[1] Patent: EP2050735, 2009, A1. Location in patent: Page/Page column 20

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) Suppliers

China 94 Europe 1 France 1 India 1 United Kingdom 2 United States 16 Global 115

Meryer (Shanghai) Chemical Technology Co., Ltd.

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Energy Chemical

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Shanghai civi chemical technology co.,Ltd

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Shanghai Topbiochem Technology Co., Ltd

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View Lastest Price from 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) 199336-83-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

Shanghai Rlavie Technology Co ltd

Product: tert-butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate 199336-83-9
Price: US $0.00-0.00/kg
Min. Order: 0.0001kg
Purity: 98%min
Supply Ability: 100kgs/month
Release date: 2022-05-10

Career Henan Chemical Co

Product: 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) 199336-83-9
Price: US $0.01/KG
Min. Order: 1KG
Purity: 98%;99%
Supply Ability: 1kg； 5kg；10kg；25kg
Release date: 2020-01-07

199336-83-9, 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI)Related Search:

(R)-tert-butyl 4-(1-aminoethyl)piperidine-1-carboxylate tert-butyl (R)-3-(hydroxymethyl)-5-methoxyindoline-1-carboxylate (R)-N-Boc-3-(aminomethyl)pyrrolidine (R)-1-Boc-3-(Cyanomethyl)Piperidine (R)-1-BOC-3-(Hydroxymethyl)piperazine 3-(Methylamino)pyrrolidine (3R)-(+)-3-(METHYLAMINO)PYRROLIDINE (cis)-5-Boc-Hexahydro-pyrrolo[3,4-b]pyrrole (3S,4S)-N-Boc-3-(benzylamino)-4-hydroxypyrrolidine 1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) L-N-[(4'-BOC)PIPERIDINO]PROLINE (2S,4R)-FMOC-4-AMINO-1-BOC-PYRROLIDINE-2-CARBOXYLIC ACID (3R,4S)-1-Boc-4-Cbz-amino-3-pyrrolidinecarboxylic acid 1-Boc-3(R )-(methoxycarbonylmethyl-amino)pyrrolidine (R)-1-BOC-3-DIMETHYLAMINOPYRROLIDINE (R)-(-)-N-BOC-3-N-FMOC-AMINOPYRROLIDINE& (R)-1-BOC-3-N-(PYRIDIN-4-YLMETHYL)-AMINO-PYRROLIDINE 2,5-DIAZA-BICYCLO[2.2.1]HEPTANE-2-CARBOXYLIC ACID TERT-BUTYL ESTER

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI)

(R)-3-(Methylamino)pyrrolidine-1-carboxylic acid tert-butyl ester

tert-Butyl (3R)-3-(methylamino)pyrrolidine-1-carboxylate

(R)-1-Boc-3-(Methylamino)pyrrolidinehydrochloride

(R)-1-Boc-3-(methylamino)pyrrolidine HCl

(S)-1-Boc-3-methylaminopyrrolidine, hydrochloride

1-N-Boc-3-(R)-(Methylamino) pyrrolidine

(R)-benzyl 3-(methylamino)pyrrolidine-1-carboxylate

2-Methyl-2-propanyl methyl(3-pyrrolidinyl)carbamate

1-Pyrrolidinecarboxylicacid,3-(MethylaMino)-,1,1-diMethylethylester,(3R)-

tert-butyl (R)-3-(methylamino)pyrrolidine-1-carboxylate

ert-butyl(3R)-3-(methylamino)pyrrolidine-1-carboxylate

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethylethylester,(R)-(9CI) USP/EP/BP

1-Pyrrolidinecarboxylicacid,3-(methylamino)-,1,1-dimethyleth...

199336-83-9

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