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4-Acetylpyridine

Product Name
4-Acetylpyridine
CAS No.
1122-54-9
Chemical Name
4-Acetylpyridine
Synonyms
NSC 111;4-Acetylpyridi;4-acetyl-pyridin;4-ACETYLPYRIDINE;4-Acttylpyridine;4-acetyl pyrdine;AKOS BBS-00003233;Acetylpyridine,4-;Pyridine, 4-acetyl-;RARECHEM AH CK 0016
CBNumber
CB2130259
Molecular Formula
C7H7NO
Formula Weight
121.14
MOL File
1122-54-9.mol
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4-Acetylpyridine Property

Melting point:
13-16 °C(lit.)
Boiling point:
212 °C(lit.)
Density 
1.095 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.529(lit.)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform, Ethyl Acetate
pka
pK1: 3.505(+1) (25°C)
form 
Liquid
Specific Gravity
1.110 (20/4℃)
color 
brown-yellowish
Water Solubility 
insoluble
BRN 
107629
InChIKey
WMQUKDQWMMOHSA-UHFFFAOYSA-N
LogP
0.480
CAS DataBase Reference
1122-54-9(CAS DataBase Reference)
NIST Chemistry Reference
Ethanone, 1-(4-pyridinyl)-(1122-54-9)
EPA Substance Registry System
4-Acetylpyridine (1122-54-9)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-36/38-22
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
OB5426000
F 
8
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A21401
Product name
4-Acetylpyridine
Purity
97%
Packaging
10g
Price
$45.5
Updated
2024/03/01
Sigma-Aldrich
Product number
A21401
Product name
4-Acetylpyridine
Purity
97%
Packaging
100g
Price
$137
Updated
2024/03/01
TCI Chemical
Product number
A0113
Product name
4-Acetylpyridine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$47
Updated
2024/03/01
TCI Chemical
Product number
A0113
Product name
4-Acetylpyridine
Purity
>98.0%(GC)(T)
Packaging
250g
Price
$286
Updated
2024/03/01
Alfa Aesar
Product number
A12015
Product name
4-Acetylpyridine, 98%
Packaging
25g
Price
$33.65
Updated
2024/03/01
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4-Acetylpyridine Chemical Properties,Usage,Production

Chemical Properties

clear light yellow to brownish liquid

Uses

4-Acetylpyridine is a acetylated pyridine used in the preparation of nitrogen containing bicyclic heterocycles and other organic compounds. 4-Acetylpyridine is also present in mainstream cigarette smo ke.

Uses

4-acetylpyridine on reaction with - and 4-formylpyridine (H3FoPyS, H4FoPyS) yields semicarbazones. Reaction of acetylpyridine with thiophene-2-carboxaldehyde afforded the 2-chloro-6-ethoxy-4-β-(2-thienyl)acryloylpyridine, which was reacted with malononitrile in refluxing ethanol in the presence of piperidine as a catalyst to afford the cyanoaminopyrane derivative.

General Description

Dark amber liquid.

Air & Water Reactions

Soluble in water.

Reactivity Profile

4-Acetylpyridine is incompatible with strong oxidizing agents and strong reducing agents. . Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Fire Hazard

4-Acetylpyridine is probably combustible.

4-Acetylpyridine Preparation Products And Raw materials

Raw materials

Preparation Products

1-(3-AMINO-2-CHLORO-PYRIDIN-4-YL)-ETHANONE 4-Pyridineethanol ETHYL 2-OXO-2-(PYRIDIN-4-YL)ACETATE 5-PYRIDIN-4-YL-4H-PYRAZOLE-3-CARBOXYLIC ACID 4-(Bromoacetyl)pyridine hydrobromide PYRIDINE-4-ACETIC ACID 1-(3-AMINO-PYRIDIN-4-YL)-ETHANONE
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4-Acetylpyridine Suppliers

Americas 1 Belgium 3 Canada 2 China 339 Czech Republic 1 Europe 3 France 2 Germany 13 Hungary 1 India 56 Italy 2 Japan 5 Slovakia 1 Switzerland 2 United Kingdom 17 United States 41 USA 1 Global 490
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View Lastest Price from 4-Acetylpyridine manufacturers

Henan Fengda Chemical Co., Ltd
Product
4-Acetylpyridine 1122-54-9
Price
US $9.00-0.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-23
Zibo Shiji Zhonglian Medical Technology Co., Ltd.
Product
4-Acetylpyridine 1122-54-9
Price
US $0.00-0.00/KG
Min. Order
25KG
Purity
99.0%
Supply Ability
5000KG/th
Release date
2023-06-16
Hebei Zhanyao Biotechnology Co. Ltd
Product
4-Acetylpyridine 1122-54-9
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-10-13

1122-54-9, 4-AcetylpyridineRelated Search:

Methyl salicylate Methyl acetate Pyridine Acetylsalicylic acid Tribenuron methyl Acetylcholine Acetylspiramycin N-ACETYL-L-TYROSINE ETHYL ESTER Sulfasalazine Thiophanate-methyl Acetaminophen Chromium picolinate Kresoxim-methyl METSULFURON METHYL Acetylacetone Methyl 3-ACETYLPYRIDINE,beta-Acetylpyridine,3-ACETYLPYRIDINE 99+% 2-Acetylpyridine ,98%,2-ACETYLPYRIDINE

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  • METHYL 4-PYRIDYL KETONE FOR SYNTHESIS
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  • 4-Acetylpyridine, 98% 100GR
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  • Ketone, Methyl 4-pyridyl (7CI,8CI)
  • NSC 111
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  • 4-Acetylpyridine, >=99.5% (GC)
  • 4-Acetylpyridine Vetec(TM) reagent grade, 97%
  • Methyl-4-pyridylketon
  • 4-Acetylpyridine &gt
  • 4-Acetylpyridine ISO 9001：2015 REACH
  • 4-acetyl pyrdine
  • 1122-54-9
  • C7 and C8
  • Pyridines
  • Heterocyclic Building Blocks
  • Alphabetic
  • AA to AL
  • Analytical Chromatography Product Catalog
  • Building Blocks
  • Analytical Standards
  • Heterocycle-Pyridine series
  • Heterocyclic Compounds
  • CHIRAL CHEMICALS
  • Pyridine
  • ACETYLGROUP
  • bc0001