2-CHLOROISONICOTINAMIDE
- Product Name
- 2-CHLOROISONICOTINAMIDE
- CAS No.
- 100859-84-5
- Chemical Name
- 2-CHLOROISONICOTINAMIDE
- Synonyms
- C257;SPB 06910;ZINC00154099;Oprea1_265572;BUTTPARK 43\57-02;2-CHLOROISONICOTINAMIDE;Isonicotinamide, 2-chloro-;2-Chloropyridine-4-formamide;2-chloropyridin-4-carboxaMide;2-CHLOROPYRIDINE-4-CARBOXAMIDE
- CBNumber
- CB2131276
- Molecular Formula
- C6H5ClN2O
- Formula Weight
- 156.57
- MOL File
- 100859-84-5.mol
2-CHLOROISONICOTINAMIDE Property
- Melting point:
- 198 °C
- Boiling point:
- 312.2±27.0 °C(Predicted)
- Density
- 1.381±0.06 g/cm3(Predicted)
- storage temp.
- Store at room temperature
- pka
- 14.37±0.50(Predicted)
- form
- powder to crystal
- color
- White to Orange to Green
- CAS DataBase Reference
- 100859-84-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36/37/39
- Hazard Note
- Irritant
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C3079
- Product name
- 2-Chloroisonicotinamide
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $21
- Updated
- 2025/07/31
- Product number
- C3079
- Product name
- 2-Chloroisonicotinamide
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $65
- Updated
- 2025/07/31
- Product number
- C367383
- Product name
- 2-Chloroisonicotinamide
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 017099
- Product name
- 2-Chloroisonicotinamide
- Purity
- 95%
- Packaging
- 1g
- Price
- $14
- Updated
- 2021/12/16
- Product number
- OR29886
- Product name
- 2-Chloroisonicotinamide
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
2-CHLOROISONICOTINAMIDE Chemical Properties,Usage,Production
Synthesis
33252-30-1
100859-84-5
GENERAL STEPS: To a flame-dried, sealable 2-5 mL Pyrex reactor were added the solid reactants: 2-chloro-4-cyanopyridine (1.0 mmol) and Cs2CO3 (1.5 mmol). The reactor was sealed with a rubber septum and pyrrolidone (2 mL/mmol [0.5 M]) was injected through the septum. Subsequently, the rubber septum was replaced with a PTFE screw cap. After sealing the reactor, the reaction was heated at 130 °C for 2 hours. Upon completion of the reaction, the resulting suspension was cooled to room temperature, filtered through a diatomaceous earth pad, and eluted with a solvent mixture of CH2Cl2/MeOH (7:3) to remove inorganic salts. Finally, the filtrate was concentrated and the residue was purified by silica gel column chromatography to afford the target product 2-chloroisonicotinamide.
References
[1] Organic Letters, 2014, vol. 16, # 4, p. 1060 - 1063
[2] Green Chemistry, 2016, vol. 18, # 18, p. 4865 - 4870
[3] Green Chemistry, 2014, vol. 16, # 4, p. 2136 - 2141
[4] Tetrahedron Letters, 2012, vol. 53, # 23, p. 2860 - 2863
2-CHLOROISONICOTINAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-CHLOROISONICOTINAMIDE manufacturers
- Product
- 2-CHLOROISONICOTINAMIDE 100859-84-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-02
- Product
- 2-CHLOROISONICOTINAMIDE 100859-84-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10 tons
- Release date
- 2020-01-10
- Product
- 2-CHLOROISONICOTINAMIDE 100859-84-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 95%min
- Supply Ability
- 20kg/month
- Release date
- 2019-12-09