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2-CHLOROISONICOTINAMIDE

Product Name
2-CHLOROISONICOTINAMIDE
CAS No.
100859-84-5
Chemical Name
2-CHLOROISONICOTINAMIDE
Synonyms
C257;SPB 06910;ZINC00154099;Oprea1_265572;BUTTPARK 43\57-02;2-CHLOROISONICOTINAMIDE;Isonicotinamide, 2-chloro-;2-Chloropyridine-4-formamide;2-chloropyridin-4-carboxaMide;2-CHLOROPYRIDINE-4-CARBOXAMIDE
CBNumber
CB2131276
Molecular Formula
C6H5ClN2O
Formula Weight
156.57
MOL File
100859-84-5.mol
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2-CHLOROISONICOTINAMIDE Property

Melting point:
198 °C
Boiling point:
312.2±27.0 °C(Predicted)
Density 
1.381±0.06 g/cm3(Predicted)
storage temp. 
Store at room temperature
pka
14.37±0.50(Predicted)
form 
powder to crystal
color 
White to Orange to Green
CAS DataBase Reference
100859-84-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-22
Safety Statements 
26-36/37/39
Hazard Note 
Irritant
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C3079
Product name
2-Chloroisonicotinamide
Purity
>98.0%(T)
Packaging
1g
Price
$21
Updated
2025/07/31
TCI Chemical
Product number
C3079
Product name
2-Chloroisonicotinamide
Purity
>98.0%(T)
Packaging
5g
Price
$65
Updated
2025/07/31
TRC
Product number
C367383
Product name
2-Chloroisonicotinamide
Packaging
1g
Price
$75
Updated
2021/12/16
Oakwood
Product number
017099
Product name
2-Chloroisonicotinamide
Purity
95%
Packaging
1g
Price
$14
Updated
2021/12/16
Apolloscientific
Product number
OR29886
Product name
2-Chloroisonicotinamide
Packaging
1g
Price
$15
Updated
2021/12/16
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2-CHLOROISONICOTINAMIDE Chemical Properties,Usage,Production

Synthesis

33252-30-1

100859-84-5

GENERAL STEPS: To a flame-dried, sealable 2-5 mL Pyrex reactor were added the solid reactants: 2-chloro-4-cyanopyridine (1.0 mmol) and Cs2CO3 (1.5 mmol). The reactor was sealed with a rubber septum and pyrrolidone (2 mL/mmol [0.5 M]) was injected through the septum. Subsequently, the rubber septum was replaced with a PTFE screw cap. After sealing the reactor, the reaction was heated at 130 °C for 2 hours. Upon completion of the reaction, the resulting suspension was cooled to room temperature, filtered through a diatomaceous earth pad, and eluted with a solvent mixture of CH2Cl2/MeOH (7:3) to remove inorganic salts. Finally, the filtrate was concentrated and the residue was purified by silica gel column chromatography to afford the target product 2-chloroisonicotinamide.

References

[1] Organic Letters, 2014, vol. 16, # 4, p. 1060 - 1063
[2] Green Chemistry, 2016, vol. 18, # 18, p. 4865 - 4870
[3] Green Chemistry, 2014, vol. 16, # 4, p. 2136 - 2141
[4] Tetrahedron Letters, 2012, vol. 53, # 23, p. 2860 - 2863

2-CHLOROISONICOTINAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CHLOROISONICOTINAMIDE Suppliers

NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
ChemPur GmbH
Tel
--
Fax
--
Email
info@ChemPur.de
Country
Germany
ProdList
2737
Advantage
50
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
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View Lastest Price from 2-CHLOROISONICOTINAMIDE manufacturers

Dideu Industries Group Limited
Product
2-CHLOROISONICOTINAMIDE 100859-84-5
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-02
Career Henan Chemical Co
Product
2-CHLOROISONICOTINAMIDE 100859-84-5
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10 tons
Release date
2020-01-10
Nanjing jinheyou Trading Co., Ltd.
Product
2-CHLOROISONICOTINAMIDE 100859-84-5
Price
US $0.00/g
Min. Order
1g
Purity
95%min
Supply Ability
20kg/month
Release date
2019-12-09