2-Nitro-5-(phenylthio)aniline
- Product Name
- 2-Nitro-5-(phenylthio)aniline
- CAS No.
- 43156-47-4
- Chemical Name
- 2-Nitro-5-(phenylthio)aniline
- Synonyms
- Fenbendazole Thio Compound;2-NITRO-5-THIOPHENYL-ANILINE;2-Nitro-5-(phenylthio)aniline;2-nitro-5-phenylmercaptoaniline;2-nitro-5-phenylsulfanylaniline;3-Amino-5-nitrodiphenyl sulfide;4-phenylthio-2-aminonitrobenzene;2-nitro-5-phenylsulfanyl-aniline;2-Nitro-5-(phenylthio)benzenamine;5-Phenylthio-2-Nitroaniline (FTC)
- CBNumber
- CB2132819
- Molecular Formula
- C12H10N2O2S
- Formula Weight
- 246.29
- MOL File
- 43156-47-4.mol
2-Nitro-5-(phenylthio)aniline Property
- Melting point:
- 145-146 °C
- Boiling point:
- 472.5±35.0 °C(Predicted)
- Density
- 1.37±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO, Methanol
- form
- Solid
- pka
- -0.98±0.25(Predicted)
- color
- Orange Yellow
- EPA Substance Registry System
- Benzenamine, 2-nitro-5-(phenylthio)- (43156-47-4)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- N496990
- Product name
- 2-Nitro-5-phenylthioaniline
- Packaging
- 25g
- Price
- $250
- Updated
- 2021/12/16
- Product number
- N496990
- Product name
- 2-Nitro-5-phenylthioaniline
- Packaging
- 100g
- Price
- $770
- Updated
- 2021/12/16
- Product number
- 47903
- Product name
- 2-Nitro-5-phenylthioaniline
- Packaging
- 100g
- Price
- $1275
- Updated
- 2021/12/16
- Product number
- 47903
- Product name
- 2-Nitro-5-phenylthioaniline
- Packaging
- 10g
- Price
- $625
- Updated
- 2021/12/16
- Product number
- CHM0093944
- Product name
- 2-NITRO-5-(PHENYLTHIO)-BENZENAMINE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $703.4
- Updated
- 2021/12/16
2-Nitro-5-(phenylthio)aniline Chemical Properties,Usage,Production
Uses
2-Nitro-5-phenylthioaniline is a useful synthetic intermediate. It was used to synthesize methyl 5(6)-phenylsulfinyl-2-benzimidazolecarbamate as a potent anthelmintic.
Synthesis
1635-61-6
108-98-5
43156-47-4
In an autoclave, 255 g of 5-chloro-2-nitroaniline (78.3% purity) was suspended in 250 mL of isopropanol. After warming the reaction system to 60 °C, 95.7 g of liquid ammonia was slowly pumped into the autoclave to bring the system pressure to 9 bar. this temperature was maintained, and 161 g of phenylthiophenol (98% purity) was added dropwise at a uniform rate over a period of 1.5 h, while the reaction pressure was controlled at a constant level of 9 bar by replenishing ammonia. after 6 h, the autoclave was cooled down to room temperature and slowly relieved of pressure. The reaction mixture was separated by filtration and the autoclave was rinsed with isopropyl alcohol and the rinsate was combined with the filtrate. The combined organic phases were washed with water and dried to obtain 298.6 g of the yellow powdery product 2-nitro-5-(phenylthio)aniline, which was analyzed by HPLC with a purity of 91.2% and a yield of 96.4% of the theoretical value.
References
[1] Patent: US6552230, 2003, B1
[2] Patent: US6552230, 2003, B1
[3] Archiv der Pharmazie, 1983, vol. 316, # 7, p. 638 - 638
[4] Journal of Heterocyclic Chemistry, 2004, vol. 41, # 2, p. 273 - 276
[5] Patent: US3965113, 1976, A
2-Nitro-5-(phenylthio)aniline Preparation Products And Raw materials
Raw materials
Preparation Products
2-Nitro-5-(phenylthio)aniline Suppliers
- Tel
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- sales@chemos-group.com
- Country
- Germany
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View Lastest Price from 2-Nitro-5-(phenylthio)aniline manufacturers
- Product
- 2-Nitro-5-(phenylthio)aniline 43156-47-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 10000KGS
- Release date
- 2025-02-18
- Product
- 2-Nitro-5-(phenylthio)aniline 43156-47-4
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2020-01-09