ChemicalBook > CAS DataBase List > 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE

1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE

Product Name
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
CAS No.
6001-64-5
Chemical Name
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
Synonyms
MET;CHLOROBUTANOL HEMIHYDRATE;CHLORETONE;CHLOROBUTANOL HYDROUS;CHLORBUTE;CHLORBUTOL;MET HEMIHYDRATE;ACETONE CHLOROFORM;Chlorobutanol Base;ACETONE CHLOROFORME
CBNumber
CB2134363
Molecular Formula
C8H16Cl6O3
Formula Weight
372.93
MOL File
6001-64-5.mol
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1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Property

Melting point:
77-79 °C(lit.)
Boiling point:
173-175 °C
Flash point:
100 °C
storage temp. 
2-8°C
solubility 
Slightly soluble in water, very soluble in ethanol (96 per cent), soluble in glycerol (85 per cent).
form 
Crystalline Powder, Crystals and/or Chunks
color 
White to almost white
Water Solubility 
Soluble in ethanol, ether, chloroform, and glycerol. Insoluble in water.
Merck 
14,2129
BRN 
878167
Stability:
Stable. Generates toxic fumes on combustion. Incompatible with strong oxidizing agents.
LogP
2.074 (est)
CAS DataBase Reference
6001-64-5
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
RTECS 
UC0175000
TSCA 
Yes
HS Code 
29055900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SAB1305534
Product name
MONOCLONAL ANTI-BI-PHOSPHO-MET/HGFR(Y1234/Y1235) antibody produced in mouse
Purity
clone 6AT1877, IgG fraction of antiserum, buffered aqueous solution
Packaging
400μl
Price
$481
Updated
2024/03/01
Sigma-Aldrich
Product number
112054
Product name
1,1,1-Trichloro-2-methyl-2-propanol hemihydrate
Purity
98%
Packaging
50g
Price
$57
Updated
2024/03/01
Sigma-Aldrich
Product number
1112503
Product name
Chlorobutanol
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$491
Updated
2024/03/01
Sigma-Aldrich
Product number
Y0002029
Product name
Chlorobutanol hemihydrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
Y0002029
Price
$150
Updated
2023/01/07
Sigma-Aldrich
Product number
1.01005
Product name
1,1,1-Trichloro-2-methyl-2-propanol hemihydrate
Purity
EMPROVE? ESSENTIAL, Ph. Eur., BP, JP, NF
Packaging
1KG
Price
$221
Updated
2022/05/15
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1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Chemical Properties,Usage,Production

Chemical Properties

white crystalline solid

Uses

1,1,1-Trichloro-2-methyl-2-propanol hemihydrate in combination with dimethyl sulfone, can serve as an appropriate solvent for the freeze drying of certain parenteral organic drugs, which have an increase in many factors such as stability, dissolution rate, dosing accuracy and sterility.

Uses

Pharmaceutic aid (antimicrobial agent).

Uses

1,1,1-Trichloro-2-methyl-2-propanol hemihydrate converts benzisoxazole to α-aryloxyisobutyric acid. It forms eutectic with dimethyl sulfone, which is the most suitable media for freeze-drying due to its high solubilizing ability and a good rate of solvent removal.

brand name

Chloretone (Parke-Davis).

General Description

1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) converts benzisoxazole to α-aryloxyisobutyric acid. 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) forms eutectic with dimethyl sulfone, which is the most suitable media for freeze-drying due to its high solubilizing ability and a good rate of solvent removal.

Biochem/physiol Actions

Chlorobutanol or 1,1,1-Trichloro-2-methyl-2-propanol is a opthalmic preservative and sedative hypnotic that possess antibacterial and antifungal properties. It also decreases the conduction velocity and induces conduction failure and automaticity within isolated ventricular muscle strips as well as impacts myocardial cells by acting on cell membrane and reduces isometric tension produced by heart.

1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Suppliers

Guangzhou Yuanda New Material Co., Ltd.
Tel
19849939632
Email
2470479589@qq.com
Country
China
ProdList
3992
Advantage
58
Jiangxi Boye Medical Technology Co., Ltd
Tel
027-18971341812/18971341812 18971341812
Fax
027-81625225
Email
anikay@boyechemicals.com
Country
China
ProdList
659
Advantage
58
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
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69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
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56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
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View Lastest Price from 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Chlorobutanol 6001-64-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%~101.0%
Supply Ability
5000kg/month
Release date
2021-06-18
Hebei Weibang Biotechnology Co., Ltd
Product
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE 6001-64-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-12-11
Hebei Weibang Biotechnology Co., Ltd
Product
1,1,1-Trichloro-2-Methyl-2-Propanol Hemihydrate 6001-64-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-29

6001-64-5, 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATERelated Search:


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