ChemicalBook > CAS DataBase List > 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE

1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE

Product Name
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
CAS No.
6001-64-5
Chemical Name
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
Synonyms
MET;CHLOROBUTANOL HEMIHYDRATE;CHLORETONE;CHLOROBUTANOL HYDROUS;CHLORBUTE;CHLORBUTOL;MET HEMIHYDRATE;ACETONE CHLOROFORM;Chlorobutanol Base;ACETONE CHLOROFORME
CBNumber
CB2134363
Molecular Formula
C8H16Cl6O3
Formula Weight
372.93
MOL File
6001-64-5.mol
More
Less

1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Property

Melting point:
77-79 °C(lit.)
Boiling point:
173-175 °C
Flash point:
100 °C
storage temp. 
2-8°C
solubility 
Slightly soluble in water, very soluble in ethanol (96 per cent), soluble in glycerol (85 per cent).
form 
Crystalline Powder, Crystals and/or Chunks
color 
White to almost white
Water Solubility 
Soluble in ethanol, ether, chloroform, and glycerol. Insoluble in water.
Merck 
14,2129
BRN 
878167
Stability:
Stable. Generates toxic fumes on combustion. Incompatible with strong oxidizing agents.
LogP
2.074 (est)
CAS DataBase Reference
6001-64-5
More
Less

Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
RTECS 
UC0175000
TSCA 
Yes
HS Code 
29055900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SAB1305534
Product name
MONOCLONAL ANTI-BI-PHOSPHO-MET/HGFR(Y1234/Y1235) antibody produced in mouse
Purity
clone 6AT1877, IgG fraction of antiserum, buffered aqueous solution
Packaging
400μl
Price
$481
Updated
2024/03/01
Sigma-Aldrich
Product number
112054
Product name
1,1,1-Trichloro-2-methyl-2-propanol hemihydrate
Purity
98%
Packaging
50g
Price
$57
Updated
2024/03/01
Sigma-Aldrich
Product number
1112503
Product name
Chlorobutanol
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$491
Updated
2024/03/01
Sigma-Aldrich
Product number
Y0002029
Product name
Chlorobutanol hemihydrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
Y0002029
Price
$150
Updated
2023/01/07
Sigma-Aldrich
Product number
1.01005
Product name
1,1,1-Trichloro-2-methyl-2-propanol hemihydrate
Purity
EMPROVE? ESSENTIAL, Ph. Eur., BP, JP, NF
Packaging
1KG
Price
$221
Updated
2022/05/15
More
Less

1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Chemical Properties,Usage,Production

Chemical Properties

white crystalline solid

Uses

1,1,1-Trichloro-2-methyl-2-propanol hemihydrate in combination with dimethyl sulfone, can serve as an appropriate solvent for the freeze drying of certain parenteral organic drugs, which have an increase in many factors such as stability, dissolution rate, dosing accuracy and sterility.

Uses

Pharmaceutic aid (antimicrobial agent).

Uses

1,1,1-Trichloro-2-methyl-2-propanol hemihydrate converts benzisoxazole to α-aryloxyisobutyric acid. It forms eutectic with dimethyl sulfone, which is the most suitable media for freeze-drying due to its high solubilizing ability and a good rate of solvent removal.

brand name

Chloretone (Parke-Davis).

General Description

1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) converts benzisoxazole to α-aryloxyisobutyric acid. 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) forms eutectic with dimethyl sulfone, which is the most suitable media for freeze-drying due to its high solubilizing ability and a good rate of solvent removal.

Biochem/physiol Actions

Chlorobutanol or 1,1,1-Trichloro-2-methyl-2-propanol is a opthalmic preservative and sedative hypnotic that possess antibacterial and antifungal properties. It also decreases the conduction velocity and induces conduction failure and automaticity within isolated ventricular muscle strips as well as impacts myocardial cells by acting on cell membrane and reduces isometric tension produced by heart.

1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Suppliers

Belgium 2 Brazil 1 China 168 France 2 Germany 6 India 34 Japan 4 Latvia 2 Poland 1 Switzerland 3 The Netherlands 1 United Arab Emirates 1 United Kingdom 7 United States 31 Global 263
Guangzhou Yuanda New Material Co., Ltd.
Tel
19849939632; 19849939632
Email
2470479589@qq.com
Country
China
ProdList
3580
Advantage
58
Shanghai Heng Pan Biological Medicine Co., LTD
Tel
18217762875
Email
2136632918@qq.com
Country
China
ProdList
41
Advantage
58
Jiangxi Boye Medical Technology Co., Ltd
Tel
18971341812/18971341812 18971341812
Fax
027-81625225
Email
anikay@boyechemicals.com
Country
China
ProdList
634
Advantage
58
Hubei widely chemical technology Co., Ltd.
Tel
027-83778895 18602735115
Fax
027-51119224
Email
18602735115@163.com
Country
China
ProdList
1999
Advantage
64
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15848
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
Shanghai Hanhong Scientific Co.,Ltd.
Tel
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18739
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4941
Advantage
60
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25014
Advantage
65
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai CanSpecsci Instrument Co., Ltd.
Tel
400-6087598 15021221957
Fax
4006087598-8012
Email
order@canspecsci.com
Country
China
ProdList
2071
Advantage
56
Shanghai Balmxy Pharmaceutical Co., Ltd
Tel
021-24206007 13764915196
Fax
86-021-23027023
Email
sales@balmxy.com
Country
China
ProdList
6730
Advantage
55
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5223
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10015
Advantage
53
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8147
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
13096311329 028-88469284 616445927
Fax
028-88469284
Email
616445927@qq.com
Country
China
ProdList
2876
Advantage
50
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9503
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9958
Advantage
56
Hangzhou Dingyan Chem Co., LTD
Tel
0571-0571-87157530-8001-8006 18049756717
Fax
0571-87156470
Email
sales@dingyanchem.com
Country
China
ProdList
1997
Advantage
58
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9947
Advantage
58
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20810
Advantage
60
Shanghai ChengShao Biological Technology Co., Ltd.
Tel
021-61847300 13341622919
Fax
021-61847300
Email
shcss01@163.com
Country
China
ProdList
4809
Advantage
58
Grader reagent
Tel
18221735425
Email
sales@xinpingchem.com
Country
China
ProdList
9951
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29797
Advantage
68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Wellman Pharmaceutical Group Limited
Tel
027-027-83778875 15807197853
Fax
027-83991220
Email
15807197853@163.com
Country
China
ProdList
3980
Advantage
58
klamar reagent
Tel
4001650900
Fax
021-64897811
Email
sales-wang@klamar-reagent.com
Country
China
ProdList
1986
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19806
Advantage
60
Guangzhou LES biological Technology Co.,Ltd.
Tel
13672434928
Fax
-
Email
3307355104@qq.com
Country
China
ProdList
3650
Advantage
58
Capot Chemical Co.,Ltd.
Tel
571-85586718 +8613336195806
Fax
+86-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
29797
Advantage
60
Shanghai Standard Technology Co.,Ltd.
Tel
021-57127007-6622 15618937986
Fax
+86 (21) 5132-0077
Email
zhaok@nature-standard.com
Country
China
ProdList
3928
Advantage
58
Aikon International Limited
Tel
025-66028182 18112977050
Fax
(3)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
15820
Advantage
58
Conier Chem & Pharma Limited
Tel
13368167990
Email
sales@conier.com
Country
China
ProdList
2809
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17997
Advantage
58
More
Less

View Lastest Price from 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Chlorobutanol 6001-64-5
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%~101.0%
Supply Ability
5000kg/month
Release date
2021-06-18
Hebei Guanlang Biotechnology Co., Ltd.
Product
1,1,1-Trichloro-2-Methyl-2-Propanol Hemihydrate 6001-64-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-10-24
Hebei Mojin Biotechnology Co., Ltd
Product
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE 6001-64-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-09-07

6001-64-5, 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATERelated Search:

2-Methyl-2-butanol 3-Chloro-1-propanol Polymethylhydrosiloxane Methylcyclohexane 2-Amino-2-methyl-1-propanol 2,2,2-TRICHLORO-1,1-DIMETHYLETHYL CHLOROFORMATE 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE tert-Butanol Chlorobutanol Chlorobutanol 1,1,1-TRICHLORO-2-PROPANOL (R)-(+)-3-HYDROXY-3-METHYL-4,4,4-TRICHLOROBUTYRIC BETA-LACTONE (S)-(-)-3-HYDROXY-3-METHYL-4,4,4-TRICHLOROBUTYRIC BETA-LACTONE 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HYDRATE BIS(2,2,2-TRICHLORO-1,1-DIMETHYLETHYL) PHOSPHOROCHLORIDATE 2,2,2-TRICHLORO-TERT-BUTOXYCARBONYL HYDRAZIDE SALOR-INT L320064-1EA AKOS 94377

  • CHLOROBUTANOL HEMIHYDRATE
  • CHLOROBUTO HEMIHYDRATE
  • CHLORETONE
  • CHLORETONE 0.5-WATER
  • CHLORETONE HEMIHYDRATE
  • CHLORBUTE
  • CHLORBUTOL
  • BETA,BETA,BETA-TRICHLORO-T-BUTANOL HEMIHYDRATE
  • BETA,BETA,BETA-TRICHLORO-TERT-BUTYL ALCOHOL HEMIHYDRATE
  • Acetonechloroform beta,beta,beta-Trichloro-tert-butyl Alcohol Chloretone
  • Chlorbutanol HeMihydrate
  • MONOCLONAL ANTI-BI-PHOSPHO-MET/HGFR(Y1234/Y1235) antibody produced in mouse
  • Proto-oncogene c-Met
  • Scatter factor receptor
  • 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate 98%
  • 1,1,1-Trichloro-2-methyl-propanol hydrat
  • 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate β,β,β-Trichloro-tert-butyl alcohol hemihydrate Acetone chloroform
  • ACETONE CHLOROFORM
  • 'ACETONE CHLOROFORM'
  • ACETONE CHLOROFORM 0.5-WATER
  • ACETONE CHLOROFORM HEMIHYDRATE
  • ACETONCHLOROFORM HEMIHYDRATE
  • 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HYDRATE
  • 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate,β,β,β-Trichloro-t-butanol, β,β,β-Trichloro-tert-butyl alcohol hemihydrate, Acetone chloroform, Chloretone, Chlorobutanol
  • Chlorobutanol (200 mg)
  • Chlorobutanol, Hydrous, NF
  • 1,1,1-Trichloro-2-Methyl-2-propanol&nbsp
  • 1,1,1-Trichloro-2-Methyl-2-propanol heMihydrate, 98% 100GR
  • 1,1,1-trichloro-2-methyl-2-propanol hemihydrate 2(
  • 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL 0.5-WATER
  • 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
  • 2,2,2-TRICHLORO-TERT BUTYL ALCOHOL
  • TRICHLORO-TER BUTANOL HEMIHYDRATE
  • TRICHLORO-TERT BUTANOL
  • N-METHYL-N-ETHYLTRYPTAMINE
  • > 100 Kghlorobutanol hemihydrate
  • 2-Methyl-1,1,1-trichloro-2-propanol hemihydrate
  • ACETONE CHLOROFORME
  • β,β,β-Trichloro-tert-butyl alcohol hemihydrate
  • CHLOROBUTANOL HEMIHYDRATE, PHARMA
  • 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL 0.5H2O
  • 2-Propanol, 1,1,1-trichloro-2-methyl-, hydrate (2:1)
  • β,β,β-trichloro-t-butanol
  • CHLORBUTOLHEMIHYDRATE
  • CHLOROBUTANOL,HEMIHYDRATE,NF
  • MET
  • MET HEMIHYDRATE
  • CHLOROBUTANOL HYDROUS
  • β,β,β-Trichloro-t-butanol, Acetone chloroform, Chloretone, Chlorobutanol, β,β,β-Trichloro-tert-butyl alcohol hemihydrate
  • Acetone chloroform, Chlorobutanol, β,β,β-Trichloro-tert-butyl alcohol hemihydrate
  • 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate,98%
  • 1,1,1-Trichloro-2-methyl-2-propanol Hemihydrate&gt
  • Chlorobutanol? (pharmaceutical grade)
  • SanlvShudingchunChlorobutanol
  • 6001-64-5 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
  • Chlorobutanol (1112503)
  • β,β,β-Trichloro-tert-butyl alcohol hemihydrate
  • 1,1,1-Trichloro-2-methylpropan-2-ol hydrate