ChemicalBook > CAS DataBase List > N,N-dimethylarginine

N,N-dimethylarginine

Product Name
N,N-dimethylarginine
CAS No.
30315-93-6
Chemical Name
N,N-dimethylarginine
Synonyms
ArginineImpurity12;H-Arg(NMe2)-OH(asym);N,N-dimethylarginine;Asymmetric dimethylarginine;Asymmetric dimethylarginine(ADMA);L-Arg(Me,Me)-OH(asymmetrical), >97%;N(omega),N(omega)-dimethyl-L-arginine;L-Ornithine, N5-[(dimethylamino)iminomethyl]-;Arginine Impurity 12(N, N-Dimethyl-L-Arginine);N5-[(Dimethylamino)iminomethyl]-L-ornithine, 97%
CBNumber
CB21351907
Molecular Formula
C8H18N4O2
Formula Weight
202.25
MOL File
30315-93-6.mol
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N,N-dimethylarginine Property

Boiling point:
340.8±52.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
DMF: 5 mg/ml; DMSO: 3 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): freely soluble
form 
A crystalline solid
pka
2.50±0.24(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00938
Product name
Dimethyl-L-arginine
Purity
≥95% (HPLC)
Packaging
100MG
Price
$224
Updated
2025/07/31
Sigma-Aldrich
Product number
SMB00938
Product name
Dimethyl-L-arginine
Purity
≥95%(HPLC)
Packaging
500MG
Price
$539
Updated
2025/07/31
ChemScene
Product number
CS-0059330
Product name
Asymmetricdimethylarginine
Purity
>98.0%
Packaging
250mg
Price
$195
Updated
2021/12/16
ChemScene
Product number
CS-0059330
Product name
Asymmetricdimethylarginine
Purity
>98.0%
Packaging
1g
Price
$495
Updated
2021/12/16
ChemScene
Product number
CS-0059330
Product name
Asymmetricdimethylarginine
Purity
>98.0%
Packaging
5g
Price
$1485
Updated
2021/12/16
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N,N-dimethylarginine Chemical Properties,Usage,Production

Uses

Metabolomics

Definition

ChEBI: A L-arginine derivative having two methyl groups both attached to the primary amino moiety of the guanidino group.

General Description

Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health. Asymmetric dimethylarginine is created in protein methylation, a common mechanism of post-translational protein modification. This reaction is catalyzed by an enzyme set called S-adenosylmethionine protein N-methyltransferases (protein methylases I and II). The methyl groups transferred to create ADMA are derived from the methyl group donor S-adenosylmethionine, an intermediate in the metabolism of homocysteine. (Homocysteine is an important blood chemical, because it is also a marker of cardiovascular disease). After synthesis, ADMA migrates into the extracellular space and then into blood plasma.

IC 50

Human Endogenous Metabolite

N,N-dimethylarginine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N,N-dimethylarginine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
N,N-dimethylarginine 30315-93-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2024-07-25

30315-93-6, N,N-dimethylarginineRelated Search:


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  • L-Ornithine, N5-[(dimethylamino)iminomethyl]-
  • ArginineImpurity12
  • H-Arg(NMe2)-OH(asym)
  • Inhibitor,Endogenous Metabolite,NOS,NO Synthase,Asymmetric dimethylarginine,inhibit,Nitric oxide synthases
  • Asymmetric dimethylarginine(ADMA)
  • 30315-93-6