ChemicalBook > CAS DataBase List > N,N-dimethylarginine

N,N-dimethylarginine

Product Name
N,N-dimethylarginine
CAS No.
30315-93-6
Chemical Name
N,N-dimethylarginine
Synonyms
ArginineImpurity12;H-Arg(NMe2)-OH(asym);N,N-dimethylarginine;Asymmetric dimethylarginine;L-Arg(Me,Me)-OH(asymmetrical), >97%;N(omega),N(omega)-dimethyl-L-arginine;L-Ornithine, N5-[(dimethylamino)iminomethyl]-;Arginine Impurity 12（N, N-Dimethyl-L-Arginine）;N5-[(Dimethylamino)iminomethyl]-L-ornithine, 97%;(S)-2-Amino-5-(3,3-dimethylguanidino)pentanoic acid
CBNumber
CB21351907
Molecular Formula
C8H18N4O2
Formula Weight
202.25
MOL File
30315-93-6.mol
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N,N-dimethylarginine Property

Boiling point:
340.8±52.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
DMF: 5 mg/ml; DMSO: 3 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): freely soluble
form 
A crystalline solid
pka
2.50±0.24(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00938
Product name
Dimethyl-L-arginine
Purity
≥95% (HPLC)
Packaging
100MG
Price
$210
Updated
2024/03/01
Sigma-Aldrich
Product number
SMB00938
Product name
Dimethyl-L-arginine
Purity
≥95%(HPLC)
Packaging
500MG
Price
$524
Updated
2024/03/01
ChemScene
Product number
CS-0059330
Product name
Asymmetricdimethylarginine
Purity
>98.0%
Packaging
1g
Price
$495
Updated
2021/12/16
ChemScene
Product number
CS-0059330
Product name
Asymmetricdimethylarginine
Purity
>98.0%
Packaging
250mg
Price
$195
Updated
2021/12/16
ChemScene
Product number
CS-0059330
Product name
Asymmetricdimethylarginine
Purity
>98.0%
Packaging
5g
Price
$1485
Updated
2021/12/16
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N,N-dimethylarginine Chemical Properties,Usage,Production

Uses

Metabolomics

Definition

ChEBI: A L-arginine derivative having two methyl groups both attached to the primary amino moiety of the guanidino group.

General Description

Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health. Asymmetric dimethylarginine is created in protein methylation, a common mechanism of post-translational protein modification. This reaction is catalyzed by an enzyme set called S-adenosylmethionine protein N-methyltransferases (protein methylases I and II). The methyl groups transferred to create ADMA are derived from the methyl group donor S-adenosylmethionine, an intermediate in the metabolism of homocysteine. (Homocysteine is an important blood chemical, because it is also a marker of cardiovascular disease). After synthesis, ADMA migrates into the extracellular space and then into blood plasma.

N,N-dimethylarginine Preparation Products And Raw materials

Raw materials

Preparation Products

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30315-93-6, N,N-dimethylarginineRelated Search:

Iodopropynyl butylcarbamate Dimethyl N,N-Dimethylaniline 2,6-Dimethylaniline ARG-ARG 4-METHOXY-B-NAPHTHYLAMIDE TRIHYD L-Arginine L-aspartate H-ARG(OH)-OH ACOH N-ALPHA-CARBAMYL-L-ARGININE glutamyl-glycyl-arginine chloromethyl ketone Homoarginine Impurity 1 DL-Arginine hydrochloride monohydrate 5-[[(DiMethylaMino)iMinoMethyl]aMino]-2-oxopentanoic Acid 1H-1,3-Diazepine-4-carboxylicacid, 2-amino-4,5,6,7-tetrahydro-, (S)- (9CI) AKA 2-Oxoarginine-13C6 NG,NGa€-Dimethyl-L-arginine-d6

  • N5-[(Dimethylamino)iminomethyl]-L-ornithine, 97%
  • N,N-dimethylarginine
  • (S)-2-Amino-5-(3,3-dimethylguanidino)pentanoic acid
  • N(omega),N(omega)-dimethyl-L-arginine
  • N,N-dimethylarginine, 2-amino-5-(3,3-dimethylguanidino)pentanoic acid L-Arg(Me, Me)-OH (asymmetrical)
  • Asymmetric dimethylarginine
  • Arginine Impurity 12（N, N-Dimethyl-L-Arginine）
  • L-Arg(Me,Me)-OH(asymmetrical), >97%
  • L-Ornithine, N5-[(dimethylamino)iminomethyl]-
  • ArginineImpurity12
  • H-Arg(NMe2)-OH(asym)
  • Inhibitor,Endogenous Metabolite,NOS,NO Synthase,Asymmetric dimethylarginine,inhibit,Nitric oxide synthases
  • 30315-93-6