ChemicalBook > CAS DataBase List > 2,6-Dimethylaniline

2,6-Dimethylaniline

Product Name
2,6-Dimethylaniline
CAS No.
87-62-7
Chemical Name
2,6-Dimethylaniline
Synonyms
2,6-DMA;NSC 7098;ai3-52358;NCI-C56188;xylylamine;2,6-Xylidin;2,6-XYLIDINE;2,6-Xyildine;amino-p-xylol;Aniline Salts
CBNumber
CB8327518
Molecular Formula
C8H11N
Formula Weight
121.18
MOL File
87-62-7.mol
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2,6-Dimethylaniline Property

Melting point:
10-12 °C(lit.)
Boiling point:
216 °C
Density 
0.984 g/mL at 25 °C(lit.)
vapor pressure 
<0.01 mm Hg ( 20 °C)
refractive index 
n20/D 1.560(lit.)
Flash point:
196 °F
storage temp. 
Store below +30°C.
solubility 
13g/l
form 
Liquid
pka
3.89(at 25℃)
color 
Clear yellow to red-brown
PH
12.5 (100g/l, H2O, 20℃)
PH Range
12.5
explosive limit
1.3-6.9%(V)
Water Solubility 
7.5 g/L (20 ºC)
Merck 
14,10084
BRN 
636332
CAS DataBase Reference
87-62-7(CAS DataBase Reference)
IARC
2B (Vol. 57) 1993
NIST Chemistry Reference
Benzenamine, 2,6-dimethyl-(87-62-7)
EPA Substance Registry System
2,6-Xylidine (87-62-7)
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Safety

Hazard Codes 
Xn,N,T
Risk Statements 
20/21/22-37/38-40-51/53
Safety Statements 
23-25-36/37-61
RIDADR 
UN 1711 6.1/PG 2
WGK Germany 
2
RTECS 
ZE9275000
8
Autoignition Temperature
490 °C
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29214910
Hazardous Substances Data
87-62-7(Hazardous Substances Data)
Toxicity
LD50 orally in Rabbit: 1290 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

H351Suspected of causing cancer

H361Suspected of damaging fertility or the unborn child

H370Causes damage to organs

H371May cause damage to organs

H373May cause damage to organs through prolonged or repeated exposure

H401Toxic to aquatic life

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P391Collect spillage. Hazardous to the aquatic environment

P307+P311IF exposed: call a POISON CENTER or doctor/physician.

P370+P378In case of fire: Use … for extinction.

P405Store locked up.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
442327
Product name
2,6-Dimethylaniline
Purity
analytical standard
Packaging
1000 mg
Price
$16.2
Updated
2021/03/22
Sigma-Aldrich
Product number
8.08671
Product name
2,6-Dimethylaniline
Purity
for synthesis
Packaging
5 mL
Price
$19.7
Updated
2021/03/22
Sigma-Aldrich
Product number
D146005
Product name
2,6-Dimethylaniline
Purity
99%
Packaging
5g
Price
$20.6
Updated
2021/03/22
Sigma-Aldrich
Product number
36766
Product name
2,6-Dimethylaniline
Purity
PESTANAL , analytical standard
Packaging
1g-r
Price
$38.4
Updated
2020/08/18
Sigma-Aldrich
Product number
36766
Product name
2,6-Dimethylaniline
Purity
PESTANAL?, analytical standard
Packaging
250MG-R
Price
$39.9
Updated
2021/03/22
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2,6-Dimethylaniline Chemical Properties,Usage,Production

Chemical Properties

clear yellow to red-brown liquid

Uses

Bupivacaine (B689560) impurity.

Definition

ChEBI: A primary arylamine that is aniline in which the hydrogens at the 2- and 6-positions are replaced by methyl groups. It is used in the production of some anasthetics and other chemicals. It is a drug metabolite of lidocaine (local anasthetic).

Synthesis Reference(s)

Journal of the American Chemical Society, 92, p. 7464, 1970 DOI: 10.1021/ja00728a038
The Journal of Organic Chemistry, 37, p. 3570, 1972

General Description

A liquid. Toxic by ingestion, inhalation and skin absorption. Slightly soluble in water. Used in pharmaceuticals, as dye intermediates and organic syntheses.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

2,6-Dimethylaniline reacts with strong oxidizing agents [Handling Chemicals Safely 1980 p. 964]. Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

May be fatal if inhaled, swallowed or absorbed through skin. Vapor or mist irritating to the eyes, mucous membranes and upper respiratory tract; causes skin irritation. Absorption into body leads to the formation of methemoglobin which, in sufficient concentration, may cause cyanosis. Onset may be delayed 2-4 hours or longer. Exposure can cause nausea, dizziness, headache, damage to the eyes, and blood effects.

Fire Hazard

Special Hazards of Combustion Products: Container explosion may occur under fire conditions. Emits toxic fumes under fire conditions.

Safety Profile

Suspected carcinogen. Moderately toxic by ingestion. Mutation data reported. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits toxic fumes of NOx. See also other xylidme entries.

Purification Methods

Convert vic-xylidine to a derivative (see below) which, after recrystallisation, is decomposed with alkali to give the free base. Dry it over KOH and fractionally distil. The acetyl derivative has m 177o, the benzoyl derivative has m 168o, and the picrate has m 180o. [Beilstein 12 H 1107, 12 IV 2521.]

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2,6-Dimethylaniline Suppliers

-Hebei DaPeng Pharm & Chem Co., Ltd.
Tel
0317-7238109-
Fax
0317-7238109
Email
sales@dpchem.com
Country
China
ProdList
1
Advantage
58
Shanghai Jovan Biochemical Technology Co. Ltd.
Tel
+86-021-61654350
Fax
+86-021-61654350
Email
1245958370@qq.com
Country
China
ProdList
2987
Advantage
50
Wuhan yuqing jiaheng pharmaceutical co. LTD
Tel
027-83855381-
Fax
027-83855381
Email
xiaozhan0503@163.com;
Country
China
ProdList
1069
Advantage
58
Wuhan Xinyang Ruihe Chemical Technology Co., Ltd.
Tel
027-83850106-
Email
366443693@QQ.COM
Country
China
ProdList
3107
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Fax
86-21-61259102
Email
sh@meryer.com
Country
China
ProdList
40264
Advantage
62
Alfa Aesar
Tel
400-610-6006; 021-67582000
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30159
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 qq:2355568890
Fax
0086-21-50182339
Email
sales@demochem.com; export1@demochem.com
Country
China
ProdList
2582
Advantage
57
Beijing dtftchem Technology Co., Ltd.
Tel
13651141086; 86(10)60275028、60275820
Fax
86 (10) 60270825
Email
dtftchem@sina.com
Country
China
ProdList
3392
Advantage
62
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View Lastest Price from 2,6-Dimethylaniline manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2,6-DiMethylaniline 87-62-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2019-12-30
career henan chemical co
Product
2,6-Dimethylaniline 87-62-7
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10MT
Release date
2018-12-16

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