GENTISEIN
- Product Name
- GENTISEIN
- CAS No.
- 529-49-7
- Chemical Name
- GENTISEIN
- Synonyms
- NSC329491;NSC-329491;NSC 329491;Gentisein(NSC 329491);Gentisein, 10 mM in DMSO;1,3,7-trihydroxyxanthen-9-one;1,3,7-Trihydroxy-9H-xanthen-9-one;9H-Xanthen-9-one,1,3,7-trihydroxy-;5-HT Receptor,Inhibitor,5-hydroxytryptamine Receptor,Serotonin Receptor,Gentisein,inhibit,1,3,7-Trihydroxyxanthone,serotonin uptake,antidepressant,metabolite
- CBNumber
- CB21409336
- Molecular Formula
- C13H8O5
- Formula Weight
- 244.2
- MOL File
- 529-49-7.mol
GENTISEIN Property
- storage temp.
- -20°C
- solubility
- DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml,Ethanol: 20 mg/ml
- form
- A solid
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- FG137911
- Product name
- Gentisein
- Packaging
- 1mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 8611CN
- Product name
- Gentisein
- Packaging
- 1mg
- Price
- $252
- Updated
- 2021/12/16
- Product number
- PXT0002139
- Product name
- GENTISEIN
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.77
- Updated
- 2021/12/16
- Product number
- CD11110128
- Product name
- Gentisein(NSC329491)
- Purity
- 95+%
- Packaging
- 5g
- Price
- $1180
- Updated
- 2021/12/16
- Product number
- CFN92398
- Product name
- Gentisein
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $312
- Updated
- 2021/12/16
GENTISEIN Chemical Properties,Usage,Production
Uses
Gentisein (NSC 329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC50 value of 4.7 μM[1][2].
Definition
ChEBI: A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3 and 7.
References
[1] Wang H, et al. Identification and determination of four metabolites of mangiferin in rat urine. J Pharm Biomed Anal. 2007;45(5):793-798. DOI:10.1016/j.jpba.2007.07.019
[2] Tzankova, Virginia et al. (2010). Inhibition of 5-HT uptake by some constituents of Hypericum annulatum in rat brain in vitro. Pharmacologyonline. 2.
GENTISEIN Preparation Products And Raw materials
Raw materials
Preparation Products
GENTISEIN Suppliers
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