ChemicalBook > CAS DataBase List > GENTISEIN

GENTISEIN

Product Name: GENTISEIN
CAS No.: 529-49-7
Chemical Name: GENTISEIN
Synonyms: NSC329491;NSC-329491;NSC 329491;Gentisein(NSC 329491);Gentisein, 10 mM in DMSO;1,3,7-trihydroxyxanthen-9-one;1,3,7-Trihydroxy-9H-xanthen-9-one;9H-Xanthen-9-one,1,3,7-trihydroxy-;5-HT Receptor,Inhibitor,5-hydroxytryptamine Receptor,Serotonin Receptor,Gentisein,inhibit,1,3,7-Trihydroxyxanthone,serotonin uptake,antidepressant,metabolite
CBNumber: CB21409336
Molecular Formula: C13H8O5
Formula Weight: 244.2
MOL File: 529-49-7.mol

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GENTISEIN Property

storage temp.: -20°C
solubility: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml,Ethanol: 20 mg/ml
form: A solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FG137911
Product name: Gentisein
Packaging: 1mg
Price: $150
Updated: 2021/12/16

AK Scientific

Product number: 8611CN
Product name: Gentisein
Packaging: 1mg
Price: $252
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PXT0002139
Product name: GENTISEIN
Purity: 95.00%
Packaging: 5MG
Price: $503.77
Updated: 2021/12/16

Crysdot

Product number: CD11110128
Product name: Gentisein(NSC329491)
Purity: 95+%
Packaging: 5g
Price: $1180
Updated: 2021/12/16

Arctom

Product number: CFN92398
Product name: Gentisein
Purity: ≥98%
Packaging: 5mg
Price: $312
Updated: 2021/12/16

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GENTISEIN Chemical Properties,Usage,Production

Uses

Gentisein (NSC 329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC50 value of 4.7 μM[1][2].

Definition

ChEBI: A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3 and 7.

References

[1] Wang H, et al. Identification and determination of four metabolites of mangiferin in rat urine. J Pharm Biomed Anal. 2007;45(5):793-798. DOI:10.1016/j.jpba.2007.07.019
[2] Tzankova, Virginia et al. (2010). Inhibition of 5-HT uptake by some constituents of Hypericum annulatum in rat brain in vitro. Pharmacologyonline. 2.

GENTISEIN Preparation Products And Raw materials

Raw materials

Preparation Products

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529-49-7, GENTISEINRelated Search:

Gamma-mangostin GENTISIN isomangiferin 1-Isomangostin Mangiferin Mangostin Neomangiferin 3-isomangostin Beta-mangostin GENTISEIN isogentisin 9H-Xanthen-9-one, 1,3,7-trimethoxy- 1-HYDROXY-3,7-DIMETHOXYXANTHONE HYDROXYCALABAXANTHONE, 9- SWERTIANIN (SWERTIAE) 5-18-05-00186 (Beilstein Handbook Reference) manglexanthone

Gentisein(NSC 329491)

1,3,7-Trihydroxy-9H-xanthen-9-one

9H-Xanthen-9-one,1,3,7-trihydroxy-

1,3,7-trihydroxyxanthen-9-one

NSC 329491

NSC329491

NSC-329491

5-HT Receptor,Inhibitor,5-hydroxytryptamine Receptor,Serotonin Receptor,Gentisein,inhibit,1,3,7-Trihydroxyxanthone,serotonin uptake,antidepressant,metabolite

Gentisein, 10 mM in DMSO

529-49-7

Xanthones