4-Amino-2,6-dibromopyridine
Uses- Product Name
- 4-Amino-2,6-dibromopyridine
- CAS No.
- 39771-34-1
- Chemical Name
- 4-Amino-2,6-dibromopyridine
- Synonyms
- SA037318;2,6-DibroMo-4-pyridinaMine;2,6-dibromopyridin-4-amine;2,6-DibroMo-4-aMinopyridine;2,6-Dibromopyridine-4-amine;4-Pyridinamine, 2,6-dibromo-;4-Amino-2,6-dibromopyridine 95+%;4-Amino-2,6-dibromopyridine ISO 9001：2015 REACH
- CBNumber
- CB21471230
- Molecular Formula
- C5H4Br2N2
- Formula Weight
- 251.91
- MOL File
- 39771-34-1.mol
4-Amino-2,6-dibromopyridine Property
- Melting point:
- 205-207 °C(Solv: hexane (110-54-3); benzene (71-43-2))
- Boiling point:
- 373.7±37.0 °C(Predicted)
- Density
- 2.147±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- solid
- pka
- 0.80±0.50(Predicted)
- color
- Off-white
- InChI
- InChI=1S/C5H4Br2N2/c6-4-1-3(8)2-5(7)9-4/h1-2H,(H2,8,9)
- InChIKey
- NTFZVUOMTODHRO-UHFFFAOYSA-N
- SMILES
- C1(Br)=NC(Br)=CC(N)=C1
- CAS DataBase Reference
- 39771-34-1
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- D426153
- Product name
- 2,6-Dibromopyridin-4-amine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- D426153
- Product name
- 2,6-Dibromopyridin-4-amine
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FA55308
- Product name
- 4-Amino-2,6-dibromopyridine
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 3H30-9-W6
- Product name
- 4-Amino-2,6-dibromopyridine
- Purity
- 95.0%
- Packaging
- 5G
- Price
- $77
- Updated
- 2021/12/16
- Product number
- CS-W002548
- Product name
- 2,6-Dibromopyridin-4-amine
- Purity
- 99.26%
- Packaging
- 10g
- Price
- $118
- Updated
- 2021/12/16
4-Amino-2,6-dibromopyridine Chemical Properties,Usage,Production
Uses
2,6-Dibromo-4-aminopyridine can be used as a pharmaceutical synthesis intermediate.
Synthesis
98027-81-7
39771-34-1
c) Synthesis of 2,6-dibromopyridin-4-amine: iron powder (1.26 g, 22.56 mmol) was slowly added to a stirring solution of 2,6-dibromo-4-nitropyridine 1-oxide (Preparation 22b, 1.68 g, 5.64 mmol) in acetic acid (16 mL) at 0 °C. The reaction mixture was stirred continuously for 1 hour at room temperature. Upon completion of the reaction, water and ethyl acetate were added to the mixture for extraction. The organic layer was separated and washed sequentially with water, saturated aqueous potassium carbonate solution and brine, followed by drying with anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure to give 2,6-dibromo-4-aminopyridine as a white solid (1.35 g, 96% yield).LRMS (m/z): 251/253/255 (M + 1)+.1H NMR (400 MHz, chloroform-d) δ ppm 4.33 (br.s., 2H), 6.68 (s, 2H).
References
[1] Patent: WO2012/41476, 2012, A1. Location in patent: Page/Page column 58-59
[2] Patent: EP2441755, 2012, A1. Location in patent: Paragraph 0174
[3] Patent: US2012/88750, 2012, A1. Location in patent: Page/Page column 22
[4] Tetrahedron Letters, 2011, vol. 52, # 44, p. 5728 - 5732
[5] Chemistry - A European Journal, 2013, vol. 19, # 41, p. 13745 - 13760
4-Amino-2,6-dibromopyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Amino-2,6-dibromopyridine manufacturers
- Product
- 4-Amino-2,6-dibromopyridine 39771-34-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-04-30
- Product
- 4-Amino-2,6-dibromopyridine 39771-34-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2019-07-05