2,6-DIBROMO-4-NITRO-PYRIDINE
- Product Name
- 2,6-DIBROMO-4-NITRO-PYRIDINE
- CAS No.
- 175422-04-5
- Chemical Name
- 2,6-DIBROMO-4-NITRO-PYRIDINE
- Synonyms
- 2,6-DIBROMO-4-NITRO-PYRIDINE;2,6-DIBROMO-4-NITRO-PYRIDINE2;Pyridine, 2,6-dibromo-4-nitro-;2,6-Dibromo-4-nitropyridine≥ 98% (HPLC);2,6-DIBROMO-4-NITRO-PYRIDINE ISO 9001：2015 REACH
- CBNumber
- CB6205757
- Molecular Formula
- C5H2Br2N2O2
- Formula Weight
- 281.89
- MOL File
- 175422-04-5.mol
2,6-DIBROMO-4-NITRO-PYRIDINE Property
- Boiling point:
- 330.0±37.0 °C(Predicted)
- Density
- 2?+-.0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- crystalline powder
- pka
- -7.58±0.10(Predicted)
- color
- Pale yellow
- InChI
- InChI=1S/C5H2Br2N2O2/c6-4-1-3(9(10)11)2-5(7)8-4/h1-2H
- InChIKey
- XIPATZUHJFQGQC-UHFFFAOYSA-N
- SMILES
- C1(Br)=NC(Br)=CC([N+]([O-])=O)=C1
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
N-Bromosuccinimide Price
- Product number
- D426048
- Product name
- 2,6-Dibromo-4-nitropyridine
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FD142976
- Product name
- 2,6-Dibromo-4-nitropyridine
- Packaging
- 1g
- Price
- $51
- Updated
- 2021/12/16
- Product number
- 057342
- Product name
- 2,6-Dibromo-4-nitropyridine
- Purity
- 90%
- Packaging
- 1g
- Price
- $62
- Updated
- 2021/12/16
- Product number
- CS-B0696
- Product name
- 2,6-dibromo-4-nitropyridine
- Purity
- 99.58%
- Packaging
- 5g
- Price
- $83
- Updated
- 2021/12/16
- Product number
- FD142976
- Product name
- 2,6-Dibromo-4-nitropyridine
- Packaging
- 2g
- Price
- $88
- Updated
- 2021/12/16
2,6-DIBROMO-4-NITRO-PYRIDINE Chemical Properties,Usage,Production
Chemical Properties
Pale yellow crystalline powder
Uses
2,6-Dibromo-4-nitropyridine
Synthesis
98027-81-7
175422-04-5
General procedure for the synthesis of 2,6-dibromo-4-nitropyridine N-oxide from 2,6-dibromo-4-nitropyridine N-oxide: to a suspension of 22.7 g (76.2 mmol) of 2,6-dibromo-4-nitropyridine N-oxide in chloroform (120 mL) was added slowly and dropwise at 5 °C phosphorus trichloride (20 mL, 229 mmol). Subsequently, the reaction mixture was heated to 75 °C and refluxed for 4 days. Upon completion of the reaction, the mixture was carefully poured into 600 mL of ice water and neutralized with sodium bicarbonate solution. The organic and aqueous layers were separated and the aqueous layer was extracted with chloroform (3 x 150 mL). The organic layers were combined and dried with magnesium sulfate and subsequently concentrated under vacuum. The residue was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate=4:1) to afford 15.5 g (72% yield) of 2,6-dibromo-4-nitropyridine as a white solid with a melting point of 122-123 °C. The residue was extracted with chloroform (3 x 150 mL) and the aqueous layer was extracted with chloroform.
References
[1] Journal of Medicinal Chemistry, 2003, vol. 46, # 7, p. 1273 - 1276
[2] Journal of Medicinal Chemistry, 2014, vol. 57, # 20, p. 8307 - 8318
[3] Tetrahedron Letters, 2007, vol. 48, # 1, p. 113 - 117
[4] Patent: WO2005/26164, 2005, A1. Location in patent: Page/Page column 41
[5] Helvetica Chimica Acta, 1997, vol. 80, # 1, p. 86 - 96
2,6-DIBROMO-4-NITRO-PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,6-DIBROMO-4-NITRO-PYRIDINE manufacturers
- Product
- 2,6-DIBROMO-4-NITRO-PYRIDINE 175422-04-5
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-08
- Product
- 2,6-DIBROMO-4-NITRO-PYRIDINE 175422-04-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 500kg
- Release date
- 2018-08-19