ChemicalBook > CAS DataBase List > D-LYSINE METHYL ESTER DIHYDROCHLORIDE

D-LYSINE METHYL ESTER DIHYDROCHLORIDE

Product Name
D-LYSINE METHYL ESTER DIHYDROCHLORIDE
CAS No.
67396-08-1
Chemical Name
D-LYSINE METHYL ESTER DIHYDROCHLORIDE
Synonyms
D-Lys-OMe 2HCl;(R)-Methyl 2,6-diaminohexanoate;D-LysineMethylEsterDihydrochloride>METHYL 2,6-DIAMINOHEXANOATE DIHYDROCHLORIDE;D-LYSINE METHYL ESTER DIHYDROCHLORIDE USP/EP/BP;(R)-Methyl 2,6-diaminohexanoate dihydrochloride;methyl (2R)-2,6-diaminohexanoate dihydrochloride;D-Lysine Methyl Ester Dihydrochloride
CBNumber
CB21475511
Molecular Formula
C7H16N2O2.2HCl
Formula Weight
0
MOL File
67396-08-1.mol
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D-LYSINE METHYL ESTER DIHYDROCHLORIDE Property

Melting point:
205 °C
refractive index 
-17 ° (C=5, H2O)
storage temp. 
Inert atmosphere,Room Temperature
Water Solubility 
Soluble in water
solubility 
Methanol (Slightly), Water (Slightly)
form 
powder to crystal
color 
White to Almost white
Stability:
Hygroscopic
CAS DataBase Reference
67396-08-1
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Safety

HS Code 
2922.41.0090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
L0201
Product name
D-Lysine Methyl Ester Dihydrochloride
Purity
>98.0%(N)(T)
Packaging
5g
Price
$122
Updated
2025/07/31
TCI Chemical
Product number
L0201
Product name
D-Lysine Methyl Ester Dihydrochloride
Purity
>98.0%(N)(T)
Packaging
25g
Price
$305
Updated
2025/07/31
TRC
Product number
L468920
Product name
D-Lysine Methyl Ester Dihydrochloride
Packaging
5g
Price
$100
Updated
2021/12/16
TRC
Product number
L468920
Product name
D-Lysine Methyl Ester Dihydrochloride
Packaging
25g
Price
$250
Updated
2021/12/16
Matrix Scientific
Product number
095091
Product name
(R)-Methyl 2,6-diaminohexanoate dihydrochloride
Purity
95+%
Packaging
1g
Price
$57
Updated
2021/12/16
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D-LYSINE METHYL ESTER DIHYDROCHLORIDE Chemical Properties,Usage,Production

Uses

D-Lysine Methyl Ester is a protected form of D-Lysine (L468930). D-Lysine is the unnatural isomer of L-Lysine (L468895) that has the ability to reduce non-enzymatic glycation in vitro. D-Lysine also exists as polypeptide chains of poly-D-lysine, a nonspecific adhesion-promoting molecule that has the potential to be a polymeric drug carrier.

Synthesis

67-56-1

657-27-2

13515-95-2

L-lysine hydrochloride (2, 5.00 g, 27.4 mmol, 1.0 eq.) and methanol (30 mL, 0.9 M) were added to a round bottom flask. The suspension was heated to reflux to completely dissolve the solid. Thionyl chloride (2.59 mL, 35.6 mmol, 1.3 eq.) was added slowly and dropwise over 15 min. The reaction mixture was kept under reflux conditions for 17 hours. Removal of most of the volatiles (~25 mL) by distillation followed by azeotropic removal of the remaining volatiles by toluene under reduced pressure afforded pure lysine methyl ester dihydrochloride (3, quantitative mass recovery, white solid), which was used directly in the next step of the reaction without further purification. The product was analyzed and the data were consistent with those reported in the literature.

References

[1] Tetrahedron Letters, 2016, vol. 57, # 4, p. 502 - 504
[2] Journal of Medicinal Chemistry, 2002, vol. 45, # 17, p. 3669 - 3683
[3] Heterocycles, 2017, vol. 94, # 5, p. 964 - 978
[4] Journal of Polymer Science, Part A: Polymer Chemistry, 2015, vol. 53, # 17, p. 2036 - 2049
[5] Molecules, 2016, vol. 21, # 1,

D-LYSINE METHYL ESTER DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from D-LYSINE METHYL ESTER DIHYDROCHLORIDE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
D-Lysine Methyl Ester Dihydrochloride 67396-08-1
Price
US $2.00-6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-08-07
Sichuan HongRi Pharma-Tech Co.,Ltd
Product
D-Lys-Ome.2Hcl 67396-08-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2024-03-24
Career Henan Chemical Co
Product
D-LYSINE METHYL ESTER DIHYDROCHLORIDE 67396-08-1
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-10

67396-08-1, D-LYSINE METHYL ESTER DIHYDROCHLORIDERelated Search:

D-Lysine D-Lysine hydrochloride L-Tyrosine Ethyl Ester Hydrochloride D-Leucine methyl ester hydrochloride H-D-TYR-OME HCL METHYL D-HOMOALANINATE HCL (S)-3-Amino-3-phenyl propionic acid methylester HCl Methyl 4-aminobutyrate hydrochloride D-Ornithine monohydrochloride L-Valine methyl ester hydrochloride D-allo-Isoleucine Ethyl Ester Hydrochloride 2-AMINO-2-METHYL-BUTYRIC ACID METHYL ESTER HYDROCHLORIDE H-D-ALLO-THR-OME HCL ETHYL 4-AMINOBUTYRATE HYDROCHLORIDE H-ABU-OME HCL N-Benzylglycine ethyl ester H-D-LYS(Z)-OH H-D-LYS(Z)-OBZL HCL

  • D-Lys-OMe 2HCl
  • methyl (2R)-2,6-diaminohexanoate dihydrochloride
  • <small>D</small>-Lysine Methyl Ester Dihydrochloride
  • METHYL 2,6-DIAMINOHEXANOATE DIHYDROCHLORIDE
  • (R)-Methyl 2,6-diaminohexanoate dihydrochloride
  • D-LysineMethylEsterDihydrochloride&gt
  • D-LYSINE METHYL ESTER DIHYDROCHLORIDE USP/EP/BP
  • (R)-Methyl 2,6-diaminohexanoate
  • 67396-08-1
  • Amino Acid Methyl Esters
  • Amino Acids
  • Amino Acids (C-Protected)
  • Biochemistry