ChemicalBook > CAS DataBase List > 2-Chloro-4,6-diphenylpyrimidine

2-Chloro-4,6-diphenylpyrimidine

Product Name
2-Chloro-4,6-diphenylpyrimidine
CAS No.
2915-16-4
Chemical Name
2-Chloro-4,6-diphenylpyrimidine
Synonyms
6-diphenylpyrimidine;2-Chloro-4,6-diphenylpyrimidine>Pyrimidine, 2-chloro-4,6-diphenyl-;2-chloro-4,6-diphenyl-1,3-pyrimidine;2-Chloro-4,6-diphenylpyrimidine ISO 9001:2015 REACH
CBNumber
CB21501298
Molecular Formula
C16H11ClN2
Formula Weight
266.72
MOL File
2915-16-4.mol
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2-Chloro-4,6-diphenylpyrimidine Property

Melting point:
113.0 to 117.0 °C
Boiling point:
469.1±14.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
powder to crystal
pka
-1.69±0.30(Predicted)
color 
White to Light yellow
CAS DataBase Reference
2915-16-4
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Safety

HS Code 
2933.59.8000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C3123
Product name
2-Chloro-4,6-diphenylpyrimidine
Purity
>98.0%(GC)
Packaging
1g
Price
$42
Updated
2025/07/31
TCI Chemical
Product number
C3123
Product name
2-Chloro-4,6-diphenylpyrimidine
Purity
>98.0%(GC)
Packaging
5g
Price
$88
Updated
2025/07/31
TRC
Product number
C370170
Product name
2-Chloro-4,6-diphenylpyrimidine
Packaging
500mg
Price
$90
Updated
2021/12/16
Matrix Scientific
Product number
098632
Product name
2-Chloro-4,6-diphenylpyrimidine
Purity
95+%
Packaging
5g
Price
$44
Updated
2021/12/16
Matrix Scientific
Product number
098632
Product name
2-Chloro-4,6-diphenylpyrimidine
Purity
95+%
Packaging
1g
Price
$14
Updated
2021/12/16
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2-Chloro-4,6-diphenylpyrimidine Chemical Properties,Usage,Production

Chemical Properties

white solid

Definition

ChEBI: 2-chloro-4,6-diphenylpyrimidine is a member of pyrimidines.

Synthesis

3764-01-0

98-80-6

2915-16-4

A mixture of 2,4,6-trichloropyrimidine (PYR, 1.3 mL, 7 mmol) and phenylboronic acid (Ph-B(OH)2, 1.5 g, 12 mmol), catalyzed by Pd(PPh3)4 (0.2 g, 0.17 mmol), was mixed in 40 mL of toluene. The mixture was transferred to a two-necked round-bottomed flask equipped with a condenser tube, and 2 M aqueous K2CO3 (40 mL), ethanol (25 mL), and toluene (80 mL) were added, and the reaction was carried out at reflux for 8 h at 110 °C under nitrogen protection. After completion of the reaction, the mixture was extracted with ethyl acetate (60 mL) and water (50 mL). The organic layer was dried with anhydrous magnesium sulfate, filtered and concentrated. The crude product was purified by silica gel column chromatography with hexane:dichloromethane (4:1) as eluent to give the intermediate 2P-PYR as a white solid. 2-Chloro-4,6-diphenylpyrimidine was further synthesized in 74% yield; white solid; 1H NMR (500 MHz, CDCl3) δ 8.13-8.14 (m, 4H), 8.01 (s, 1H), 7.51-7.55 (m, 6H); 13C NMR (500 MHz, CDCl3) δ 167.7, 162.1, 135.7, 131.7, 129.1, 127.5, 111.0.

References

[1] Journal of Organic Chemistry, 2001, vol. 66, # 21, p. 7125 - 7128
[2] Patent: WO2011/93609, 2011, A1. Location in patent: Page/Page column 17
[3] Patent: KR2015/92145, 2015, A. Location in patent: Paragraph 0265-0267
[4] Patent: CN103664906, 2016, B. Location in patent: Paragraph 0158; 0160
[5] Patent: CN103570628, 2016, B. Location in patent: Paragraph 0103-0106

2-Chloro-4,6-diphenylpyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Chloro-4,6-diphenylpyrimidine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
2-Chloro-4,6-diphenylpyrimidine 2915-16-4
Price
US $100.00-50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2024-11-13
Henan Aochuang Chemical Co.,Ltd.
Product
2-Chloro-4,6-diphenylpyrimidine 2915-16-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-27
Shanghai UCHEM Inc.
Product
2-Chloro-4,6-diphenylpyrimidine 2915-16-4
Price
US $13.00-216.00/g
Min. Order
5g
Purity
0.98
Supply Ability
25kg
Release date
2024-01-02

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