ChemicalBook > CAS DataBase List > 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid

2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid

Product Name
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid
CAS No.
391211-97-5
Chemical Name
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid
Synonyms
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid;3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoic acid;2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic acid 98%;3,4-Difluoro-2-(2-fluoro-4-iodophenylaMino)benzoic Acid;3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)aMino]benzoic Acid;Benzoic acid, 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]-;2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID;2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID;3,4-Difluoro-2-(2-fluoro-4-iodophenylamino)benzoic acid
CBNumber
CB21507957
Molecular Formula
C13H7F3INO2
Formula Weight
393.1
MOL File
391211-97-5.mol
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2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Property

Melting point:
189-191°C
Boiling point:
370.1±42.0 °C(Predicted)
Density 
1.939±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
DMSO (Sparingly), Methanol (Slightly)
form 
Solid
pka
3.25±0.36(Predicted)
color 
Off-White to Beige
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
F591960
Product name
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoicAcid
Packaging
2g
Price
$315
Updated
2021/12/16
ChemScene
Product number
CS-M1628
Product name
Benzoicacid,3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-
Purity
99.76%
Packaging
100mg
Price
$62
Updated
2021/12/16
ChemScene
Product number
CS-M1628
Product name
Benzoicacid,3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-
Purity
99.76%
Packaging
250mg
Price
$83
Updated
2021/12/16
Apolloscientific
Product number
PC408065
Product name
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoicacid
Purity
98%
Packaging
250mg
Price
$134
Updated
2021/12/16
SynQuest Laboratories
Product number
4657-K-01
Product name
3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoic acid
Packaging
250mg
Price
$155
Updated
2021/12/16
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2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Intermediate in the preparation of MEK inhibitors.

Synthesis

To a solution of methyl-3,4-diflluoro-2-((2-flluoro-4-iodophenyl)amino)benzoate (23, 6.0 g, 23.8 mmol) in methanol (80 mL) and water (80 mL) was added LiOH (7.8 g, 195 mmol). The reaction mixture was stirred at 78 C in an oil bath for 1 h. After cooling, the reaction mixture was acidified to pH = 2 with a 2 N HCl solution. The solid was filtered and washed with water to provide 2-(2-Fluoro-4-iodoanilino)-3,4-difluoro benzoic Acid (5.11 g, 96%) as a white solid.

2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Suppliers

Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
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View Lastest Price from 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid manufacturers

Career Henan Chemical Co
Product
2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID 391211-97-5
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-08-13

391211-97-5, 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic AcidRelated Search:


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  • 3,4-Difluoro-2-(2-fluoro-4-iodophenylaMino)benzoic Acid
  • 3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)aMino]benzoic Acid
  • Benzoic acid, 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]-
  • 3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoic acid
  • 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic acid 98%
  • 2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID
  • 3,4-<WBR>Difluoro-<WBR>2-<WBR>(2-<WBR>fluoro-<WBR>4-<WBR>iodophenylamino)<WBR>benzoic acid
  • 391211-97-5
  • C13H7F3INO2
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