2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid

Product Name: 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid
CAS No.: 391211-97-5
Chemical Name: 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid
Synonyms: 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid;3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoic acid;2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic acid 98%;3,4-Difluoro-2-(2-fluoro-4-iodophenylaMino)benzoic Acid;3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)aMino]benzoic Acid;Benzoic acid, 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]-;2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID;2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID;3,4-Difluoro-2-(2-fluoro-4-iodophenylamino)benzoic acid
CBNumber: CB21507957
Molecular Formula: C13H7F3INO2
Formula Weight: 393.1
MOL File: 391211-97-5.mol

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2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Property

Melting point:: 189-191°C
Boiling point:: 370.1±42.0 °C(Predicted)
Density: 1.939±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,2-8°C
solubility: DMSO (Sparingly), Methanol (Slightly)
form: Solid
pka: 3.25±0.36(Predicted)
color: Off-White to Beige

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Safety

HS Code: 2916399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: F591960
Product name: 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoicAcid
Packaging: 2g
Price: $315
Updated: 2021/12/16

Matrix Scientific

Product number: 099339
Product name: 3,4-Difluoro-2-((2-fluoro-4-iodophenyl)-amino)benzoic acid
Purity: 95+%
Packaging: 1g
Price: $353
Updated: 2021/12/16

Apolloscientific

Product number: PC408065
Product name: 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoicacid
Purity: 98%
Packaging: 1g
Price: $286
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4657-K-01
Product name: 3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoic acid
Packaging: 1g
Price: $295
Updated: 2021/12/16

AK Scientific

Product number: 5091AB
Product name: 3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)benzoicacid
Packaging: 5g
Price: $752
Updated: 2021/12/16

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2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Intermediate in the preparation of MEK inhibitors.

Synthesis

To a solution of methyl-3,4-diflluoro-2-((2-flluoro-4-iodophenyl)amino)benzoate (23, 6.0 g, 23.8 mmol) in methanol (80 mL) and water (80 mL) was added LiOH (7.8 g, 195 mmol). The reaction mixture was stirred at 78 C in an oil bath for 1 h. After cooling, the reaction mixture was acidified to pH = 2 with a 2 N HCl solution. The solid was filtered and washed with water to provide 2-(2-Fluoro-4-iodoanilino)-3,4-difluoro benzoic Acid (5.11 g, 96%) as a white solid.

2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Suppliers

Canada 1 China 84 India 2 United Kingdom 1 United States 8 Global 96

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View Lastest Price from 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid manufacturers

Career Henan Chemical Co

Product: 2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID 391211-97-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-13

391211-97-5, 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic AcidRelated Search:

N-(2-FLUOROPHENYL)ANTHRANILIC ACID 4-FLUORO-2-PHENYLAMINO-BENZOIC ACID 2-Fluoro-4-iodoaniline 2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID 4-Amino-3-chlorophenol 3-FLUORODIPHENYLAMINE 2-AMINO-3,4-DIFLUOROBENZOIC ACID

2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID

2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid

3,4-Difluoro-2-(2-fluoro-4-iodophenylaMino)benzoic Acid

3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)aMino]benzoic Acid

Benzoic acid, 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]-

3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoic acid

2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic acid 98%

2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID

3,4-Difluoro-2-(2-fluoro-4-iodophenylamino)benzoic acid

391211-97-5

C13H7F3INO2

Aromatics

Intermediates & Fine Chemicals

Pharmaceuticals