2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid
- Product Name
- 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid
- CAS No.
- 391211-97-5
- Chemical Name
- 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid
- Synonyms
- 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid;3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoic acid;2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic acid 98%;3,4-Difluoro-2-(2-fluoro-4-iodophenylaMino)benzoic Acid;3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)aMino]benzoic Acid;Benzoic acid, 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]-;2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID
- CBNumber
- CB21507957
- Molecular Formula
- C13H7F3INO2
- Formula Weight
- 393.1
- MOL File
- 391211-97-5.mol
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Property
- Melting point:
- 189-191°C
- Boiling point:
- 370.1±42.0 °C(Predicted)
- Density
- 1.939±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- DMSO (Sparingly), Methanol (Slightly)
- form
- Solid
- pka
- 3.25±0.36(Predicted)
- color
- Off-White to Beige
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F591960
- Product name
- 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoicAcid
- Packaging
- 2g
- Price
- $315
- Updated
- 2021/12/16
- Product number
- 099339
- Product name
- 3,4-Difluoro-2-((2-fluoro-4-iodophenyl)-amino)benzoic acid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $353
- Updated
- 2021/12/16
- Product number
- PC408065
- Product name
- 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoicacid
- Purity
- 98%
- Packaging
- 1g
- Price
- $286
- Updated
- 2021/12/16
- Product number
- 4657-K-01
- Product name
- 3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoic acid
- Packaging
- 1g
- Price
- $295
- Updated
- 2021/12/16
- Product number
- 5091AB
- Product name
- 3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)benzoicacid
- Packaging
- 5g
- Price
- $752
- Updated
- 2021/12/16
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Uses
Intermediate in the preparation of MEK inhibitors.
Synthesis
To a solution of methyl-3,4-diflluoro-2-((2-flluoro-4-iodophenyl)amino)benzoate (23, 6.0 g, 23.8 mmol) in methanol (80 mL) and water (80 mL) was added LiOH (7.8 g, 195 mmol). The reaction mixture was stirred at 78 C in an oil bath for 1 h. After cooling, the reaction mixture was acidified to pH = 2 with a 2 N HCl solution. The solid was filtered and washed with water to provide 2-(2-Fluoro-4-iodoanilino)-3,4-difluoro benzoic Acid (5.11 g, 96%) as a white solid.
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid Suppliers
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- +1-833-552-7181
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- United States
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View Lastest Price from 2-(2-Fluoro-4-iodoanilino)-3,4-difluorobenzoic Acid manufacturers
- Product
- 2-(N-2''-FLURO-4''-IODOPHENYL)AMINO-3,4-DIFLUORO BENZOIC ACID 391211-97-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20kg
- Release date
- 2018-08-13