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tert-Butyl 3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate

Product Name
tert-Butyl 3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate
CAS No.
877402-43-2
Chemical Name
tert-Butyl 3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate
Synonyms
N-Boc triazolo[4,3-a]pyrazine Impurity;tert-Butyl 3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate;3-Trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazine-7-carboxylic acid tert-butyl ester;1,2,4-Triazolo[4,3-a]pyrazine-7(8H)-carboxylic acid, 5,6-dihydro-3-(trifluoromethyl)-, 1,1-dimethylethyl ester
CBNumber
CB21512708
Molecular Formula
C11H15F3N4O2
Formula Weight
292.26
MOL File
877402-43-2.mol
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tert-Butyl 3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate Property

Boiling point:
356.9±52.0 °C(Predicted)
Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Dichloromethane, Ethyl Acetate
form 
Solid
pka
0.25±0.20(Predicted)
color 
White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B675175
Product name
tert-Butyl3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate
Packaging
100mg
Price
$55
Updated
2021/12/16
TRC
Product number
B675175
Product name
tert-Butyl3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate
Packaging
1g
Price
$355
Updated
2021/12/16
Chemcia Scientific
Product number
AA10-2470
Product name
3-Trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazine-7-carboxylicacidtert-butylester
Purity
95%
Packaging
1g
Price
$395
Updated
2021/12/16
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tert-Butyl 3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate Chemical Properties,Usage,Production

Uses

tert-Butyl 3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate is an intermediate in the synthesis of Sitagliptin Triazecine Analog (S491015). Sitagliptin Triazecine Analog is related to the family of Sitagliptin compounds which has recently been approved for the therapy of type II diabetes.

tert-Butyl 3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-Butyl 3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate Suppliers

877402-43-2, tert-Butyl 3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylateRelated Search:


  • tert-Butyl 3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-carboxylate
  • 3-Trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazine-7-carboxylic acid tert-butyl ester
  • 1,2,4-Triazolo[4,3-a]pyrazine-7(8H)-carboxylic acid, 5,6-dihydro-3-(trifluoromethyl)-, 1,1-dimethylethyl ester
  • N-Boc triazolo[4,3-a]pyrazine Impurity
  • 877402-43-2
  • C11H15F3N4O2
  • API intermediates