3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine

Uses

Product Name: 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
CAS No.: 486460-21-3
Chemical Name: 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Synonyms: 3-Trifluoromethyl-5,6,7,8...;TAP-4 (Sitagliptin Intermediat;TAP-4 (Sitagliptin Intermediate);3-(TrifluoroMethyl)-5,6,7,8-tetrahydro-[1,2,4];3-trifluoro methyl-[1,2,4]triazole[4,3-a]piperazine;3-(Trifluoromethyl)[1,2,4]triazolo[4,3-a]piperazine;3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine;3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a...;3-(TrifluoroMethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyra;3-(Trifluoromethyl)-1,2,4-triazolo[4,3-a]piperazine Hydrochloride
CBNumber: CB5809828
Molecular Formula: C6H7F3N4
Formula Weight: 192.14
MOL File: 486460-21-3.mol

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3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Property

Boiling point:: 266∶C
Density: 1.72
Flash point:: 115∶C
storage temp.: 2-8°C(protect from light)
form: solid
pka: 6.27±0.20(Predicted)
color: Yellow
CAS DataBase Reference: 486460-21-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: T796983
Product name: 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Packaging: 100mg
Price: $75
Updated: 2021/12/16

Apolloscientific

Product number: PC1232
Product name: 5,6,7,8-Tetrahydro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine
Packaging: 250mg
Price: $15
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-3-Y3
Product name: 3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine
Packaging: 250mg
Price: $16
Updated: 2021/12/16

Matrix Scientific

Product number: 068416
Product name: 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
Purity: >95%
Packaging: 1g
Price: $25
Updated: 2021/12/16

Apolloscientific

Product number: PC1232
Product name: 5,6,7,8-Tetrahydro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine
Packaging: 1g
Price: $37
Updated: 2021/12/16

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3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Chemical Properties,Usage,Production

Uses

3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine is primarily used as an important intermediate in organic synthesis. The introduction of the trifluoromethyl group imparts excellent chemical and thermal stability to this compound, allowing it to react under relatively harsh conditions. Furthermore, it possesses certain biological and pharmacological activities, making it a potential candidate compound for drug development. Therefore, it has wide applications in organic synthesis, materials science, and drug development.

Chemical Properties

White crystalline powder

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Preparation Products And Raw materials

Raw materials

Hydrazinium hydroxide solution Ethanol Palladium Polyphosphoric acid Trifluoroacetic anhydride 2-Chloropyrazine

Preparation Products

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3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Suppliers

China 197 Germany 2 India 9 Switzerland 1 United Kingdom 1 United States 17 Global 227

J & K SCIENTIFIC LTD.

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Pure Chemistry Scientific Inc.

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View Lastest Price from 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride 486460-21-3
Price: US $0.10/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 1000 tons
Release date: 2020-04-24

Zhuozhou Wenxi import and Export Co., Ltd

Product: (trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazlol[4,3-a]pyrazine 486460-21-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: (trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazlol[4,3-a]pyrazine 486460-21-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

486460-21-3, 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazineRelated Search:

Tetramethylpyrazine Terazosin Prazosin Levomepromazine hydrochloride Pyrazine Terazosin hydrochloride Doxazosin Sitagliptin Sitagliptin phosphate monohydrate Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate Sitagliptin S-IsoMer 3-(tert-butoxycarbonyl aMino)-4-(2,4,5-trifluoro phenyl)butanoic acid 1-(2,4,5-trifluorophenyl)propan-2-one (S)-1-(2,4,5-trifluorophenyl)propan-2-amine hydrochloride Methyl 3-aMino-4-(2,4,5-trifluorophenyl)butanoate tert-butyl 4-oxo-4-(3-(trifluoroMethyl)-5,6-dihydro-[1,2,4]triazolo [4,3-a]pyrazin-7(8H)-yl)-1-(2,4,5-trifluorophenyl) butan-2-ylcarbaMate (S)-methyl 3-amino-4-(2,4,5-trifluoro phenyl) butanoate 1-(2,4,5-trifluorophenyl)propan-2-amine hydrochloride

3-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZINE PHOSPHATE SALT 98% MINHPLC

3-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZINE HYDRO

3-trifluoro methyl-[1,2,4]triazole[4,3-a]piperazine

(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazlol[4,3-a]pyrazine

3-Trifluoromethyl-5,6,7,8...

5,6,7,8-Tetrahydro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine

3-(TrifluoroMethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyra

3-(Trifluoromethyl)[1,2,4]triazolo[4,3-a]piperazine

TAP-4 (Sitagliptin Intermediate)

3-(TrifluoroMethyl)-5,6,7,8-tetrahydro-[1,2,4]

3-(TrifluoroMethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine hydrochloride, 98+%

1,2,4-Triazolo[4,3-a]pyrazine,5,6,7,8-tetrahydro-3-(trifluoroMethyl)-

3-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO-1,2,4-TRIAZOLO-[4,3-A]PYRAZINE

3-(Trifluoromethyl)-1,2,4-triazolo[4,3-a]piperazine Hydrochloride

3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine

3-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZINE PHOSPHATE SALT 98%

3-(TRIFLUOROMETHYL)-5,6,7,8-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-A]PYRAZINE PHOSPHATE SALT MINHPLC

TAP-4 (Sitagliptin Intermediat

3- (trifluoromethyl) -5,6,7, 8-tetrahydro-[1,2,4] triazole [4,3-a] pyrazine hydrochloride

3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazin-7-ium

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a...

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[l,2,4]triazolo[4,3-a]pyrazine

3-(trifluoro methyl)-5,6,7,8-tetrahydro- [1,2,4] triazolo [4,3-α] pyrazine hydrochloride

3-(Trifluromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a] pyrazine

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-A]pyrazine HCL form, 98%

486460-21-3

C6H7N4F3PO4

C6H7F3N4HCl

C6H7F3N4

Heterocyclic Building Blocks

Amines and Anilines

Heterocycles