5-AMINOTHIAZOLE HCL
- Product Name
- 5-AMINOTHIAZOLE HCL
- CAS No.
- 942631-51-8
- Chemical Name
- 5-AMINOTHIAZOLE HCL
- Synonyms
- Thiazol-5-ylaMine;5-Thiazolamine HCl;5-AMINOTHIAZOLE HCL;thiazol-5-aMine hydrochloride;5-Aminothiazole hydrochloride;Thiazol-5-ylamine hydrochloride;1,3-thiazol-5-amine hydrochloride;5-Thiazolamine, hydrochloride (1:1)
- CBNumber
- CB21519257
- Molecular Formula
- C3H5ClN2S
- Formula Weight
- 136.6
- MOL File
- 942631-51-8.mol
5-AMINOTHIAZOLE HCL Property
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- Appearance
- White to light yellow Solid
- InChI
- InChI=1S/C3H4N2S.ClH/c4-3-1-5-2-6-3;/h1-2H,4H2;1H
- InChIKey
- WFJPRXNQDKBTPT-UHFFFAOYSA-N
- SMILES
- S1C(N)=CN=C1.Cl
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- T344223
- Product name
- 5-ThiazolamineHydrochloride
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- OR51952
- Product name
- 5-Aminothiazolehydrochloride
- Packaging
- 1g
- Price
- $160
- Updated
- 2021/12/16
- Product number
- FA10572
- Product name
- 5-Aminothiazole hydrochloride
- Packaging
- 500mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- 7H70-5-95
- Product name
- 5-Aminothiazolehydrochloride
- Packaging
- 1g
- Price
- $176
- Updated
- 2021/12/16
- Product number
- W9667
- Product name
- 5-Thiazolaminehydrochloride
- Packaging
- 1g
- Price
- $181
- Updated
- 2021/12/16
5-AMINOTHIAZOLE HCL Chemical Properties,Usage,Production
Synthesis
942631-50-7
942631-51-8
General procedure for the synthesis of 5-aminothiazole hydrochloride from tert-butyl thiazole-5-carbamate: To a stirred solution of tert-butyl thiazole-5-carbamate (379, 300 mg, 1.5 mmol) in methanol (5 mL), protected by argon at 0°C, a 1,4-dioxane solution (5 mL) in 4N HCl was slowly added. The reaction mixture was gradually warmed up to room temperature and stirring was continued for 3 hours. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the volatile solvent was removed under reduced pressure to give the crude product. The crude product was washed with n-pentane (2 × 5 mL) and subsequently dried under reduced pressure to afford 5-aminothiazole hydrochloride (380, 150 mg, HCl salt) as a light yellow solid.TLC conditions: 50% ethyl acetate/hexane (Rf 0.1); 1H-NMR (DMSO-d6, 500 MHz) data: δ 9.10 (s, 1H), 7.22 (s. 1H).
References
[1] Patent: WO2007/71955, 2007, A1. Location in patent: Page/Page column 47
[2] Patent: WO2014/41175, 2014, A1. Location in patent: Page/Page column 55
[3] Patent: WO2015/138895, 2015, A1. Location in patent: Paragraph 000310
5-AMINOTHIAZOLE HCL Preparation Products And Raw materials
Raw materials
Preparation Products
5-AMINOTHIAZOLE HCL Suppliers
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