ChemicalBook > CAS DataBase List > BOC-GLYCINE TERT-BUTYL ESTER
BOC-GLYCINE TERT-BUTYL ESTER
- Product Name
- BOC-GLYCINE TERT-BUTYL ESTER
- CAS No.
- 111652-20-1
- Chemical Name
- BOC-GLYCINE TERT-BUTYL ESTER
- Synonyms
- N-Boc-gL;BOC-GLY-OTBU;N-BOC-Gly-OtBu;Boc-Gly-Ot<;Boc-Gly-Otbu-OH;Boc-Gly-OtBu, ≥98%;Boc-Gly-OtBu;BOC-GLYCINE T-BUTYL ESTER;BOC-GLYCINE TERT-BUTYL ESTER;(Tert-Butoxy)Carbonyl Gly-OtBu
- CBNumber
- CB2157582
- Molecular Formula
- C11H21NO4
- Formula Weight
- 231.29
- MOL File
- 111652-20-1.mol
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BOC-GLYCINE TERT-BUTYL ESTER Property
- Melting point:
- 66-68 °C(lit.)
- Boiling point:
- 306.0±25.0 °C(Predicted)
- Density
- 1.023
- storage temp.
- 2-8°C
- solubility
- very soluble in Methanol
- form
- powder to crystal
- pka
- 11.06±0.46(Predicted)
- color
- White to Almost white
- Water Solubility
- 1.05g/L at 20℃
- BRN
- 5002580
- InChIKey
- ZDKFMHKWZATBMR-UHFFFAOYSA-N
- LogP
- 2.21 at 25℃
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Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-51
- Safety Statements
- 20/21-29/56
- WGK Germany
- 3
- HS Code
- 29241990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H401Toxic to aquatic life
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P330Rinse mouth.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 423297
- Product name
- Boc-Gly-OtBu
- Purity
- 99%
- Packaging
- 5g
- Price
- $134
- Updated
- 2023/06/20
TCI Chemical
- Product number
- B4156
- Product name
- N-(tert-Butoxycarbonyl)glycine tert-Butyl Ester
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 1g
- Price
- $20
- Updated
- 2025/07/31
TCI Chemical
- Product number
- B4156
- Product name
- N-(tert-Butoxycarbonyl)glycine tert-Butyl Ester
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 5g
- Price
- $54
- Updated
- 2025/07/31
Usbiological
- Product number
- 265310
- Product name
- Boc-glycine tert-butyl ester
- Packaging
- 1g
- Price
- $358
- Updated
- 2021/12/16
TRC
- Product number
- B656140
- Product name
- Boc-Gly-OtBu
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
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BOC-GLYCINE TERT-BUTYL ESTER Chemical Properties,Usage,Production
Chemical Properties
Whtie powder
Uses
peptide synthesis
reaction suitability
reaction type: Boc solid-phase peptide synthesis
Synthesis
24424-99-5
27532-96-3
111652-20-1
Example 1 (Example of reaction formula (1)) [13]: tert-butyl glycinate hydrochloride (10.0 g, 59.7 mmol) was suspended in toluene (46.2 ml), heated to 60 °C and then triethylamine (6.51 g, 64.3 mmol) was added, and the reaction was stirred for 0.5 hours. Subsequently, a solution of di-tert-butyl dicarbonate (10.0 g, 45.9 mmol) in toluene (11.6 ml) was added slowly and dropwise to the reaction mixture and the reaction was continued for 6 hours. After completion of the reaction, it was quenched by addition of water (30 ml) and the organic layer was separated. The organic layer was distilled by azeotropic distillation with n-hexane to remove the solvent to afford tert-butyl N-Boc-glycinate (10.6 g, 45.9 mmol, 100% yield). The structure of the product was confirmed by 1H-NMR analysis.
References
[1] Patent: CN103068795, 2016, B. Location in patent: Paragraph 0119; 0120; 0121; 0122; 0123; 0124
[2] Synthesis, 1987, # 3, p. 223 - 225
[3] The Journal of organic chemistry, 2002, vol. 67, # 24, p. 8291 - 8298
BOC-GLYCINE TERT-BUTYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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BOC-GLYCINE TERT-BUTYL ESTER Suppliers
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- 18210857532; 18210857532
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View Lastest Price from BOC-GLYCINE TERT-BUTYL ESTER manufacturers
Sichuan HongRi Pharma-Tech Co.,Ltd
- Product
- Boc-Gly-OtBU 111652-20-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2023-09-15
Henan Aochuang Chemical Co.,Ltd.
- Product
- Boc-Gly-OtBu 111652-20-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-28
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- Boc-Gly-OtBu 111652-20-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
111652-20-1, BOC-GLYCINE TERT-BUTYL ESTERRelated Search:
BOC-Glycine
N-Boc-L-phenylalaninal
N-Boc-Ethylenediamine
N-(tert-Butoxycarbonyl)-4-piperidone
Boc-L-glutamic acid 1-tert-butyl ester
(S)-N-ALPHA-T-BUTYLOXYCARBONYL-PYROGLUTAMIC ACID T-BUTYL ESTER
Boc-Asp-OtBu
BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER
N-1-BOC-N-4-CBZ-2-PIPERAZINECARBOXYLIC ACID T-BUTYL ESTER
Glycine
BOC-SER(TBU)-OH
BOC-D-ASP-OTBU
BOC-ORN-OTBU HCL
N-BOC-4-NITRO-L-PHENYLALANINE-T-BUTYL ESTER
BOC-GLU(OSU)-OTBU
BOC-L-THIOCITRULLINE-OTBU
BOC-ALA-OTBU
BOC-D-GLU-OTBU