ChemicalBook > CAS DataBase List > Tetrakis(hydroxymethyl)phosphonium chloride

Tetrakis(hydroxymethyl)phosphonium chloride

Product Name: Tetrakis(hydroxymethyl)phosphonium chloride
CAS No.: 124-64-1
Chemical Name: Tetrakis(hydroxymethyl)phosphonium chloride
Synonyms: THPC;SQJGLHL;THPS-UPC;meso-THPC;pyrosettkc;nci-c55061;AURORA KA-1157;HISHICOLIN THPC;tetramethylolphosphonium chloride;tetrakis(hydroxymethyl)phosphonium
CBNumber: CB2166508
Molecular Formula: C4H12ClO4P
Formula Weight: 190.56
MOL File: 124-64-1.mol

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Tetrakis(hydroxymethyl)phosphonium chloride Property

Melting point:: 154°C
Boiling point:: 115°C/760mmHg
Density: 1.341 g/mL at 25 °C
vapor pressure: 0Pa at 25℃
refractive index: n20/D 1.512
form: Solution
pka: 6.05[at 20 ℃]
color: Clear light pink or yellow-green
Water Solubility: >=10 g/100 mL at 20 ºC
BRN: 3631669
InChI: InChI=1S/C4H12O4P.ClH/c5-1-9(2-6,3-7)4-8;/h5-8H,1-4H2;1H/q+1;/p-1
InChIKey: AKXUUJCMWZFYMV-UHFFFAOYSA-M
SMILES: [P+](CO)(CO)(CO)CO.[Cl-]
LogP: -9.8
CAS DataBase Reference: 124-64-1(CAS DataBase Reference)
EPA Substance Registry System: Tetrakis(hydroxymethyl)phosphonium chloride (124-64-1)

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Safety

Hazard Codes: T,N
Risk Statements: 21-25-38-41-42/43-51/53
Safety Statements: 22-26-36/37/39-45-60-61-23
RIDADR: UN 2810 6.1/PG 3
WGK Germany: 3
RTECS: TA2450000
HazardClass: 8
PackingGroup: III
HS Code: 29319019
Hazardous Substances Data: 124-64-1(Hazardous Substances Data)
Toxicity: mammal (species unspecified),LD50,oral,400mg/kg (400mg/kg),Kobunshi. High Polymers. Vol. 24, Pg. 788, 1975.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 404861
Product name: Tetrakis(hydroxymethyl)phosphonium chloride solution
Purity: 80% in H2O
Packaging: 100ml
Price: $77.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: 404861
Product name: Tetrakis(hydroxymethyl)phosphonium chloride solution
Purity: 80% in H2O
Packaging: 500ml
Price: $227
Updated: 2025/07/31

TCI Chemical

Product number: T0607
Product name: Tetrakis(hydroxymethyl)phosphonium Chloride (ca. 80% in Water)
Packaging: 25mL
Price: $19
Updated: 2021/12/16

TCI Chemical

Product number: T0607
Product name: Tetrakis(hydroxymethyl)phosphonium Chloride (ca. 80% in Water)
Packaging: 500mL
Price: $162
Updated: 2021/12/16

TRC

Product number: T298578
Product name: Tetrakis(hydroxymethyl)phosphonium Chloride (ca. 80% in Water)
Packaging: 1mL
Price: $45
Updated: 2021/12/16

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Tetrakis(hydroxymethyl)phosphonium chloride Chemical Properties,Usage,Production

Chemical Properties

Clear light pink or yellow-green solution

Uses

Flame-retarding agent for cotton fabrics. May be used in combination with triethylolamine and urea (Roxel process) or with triethanolamine and tris(1-aziridinyl) phosphine oxide.

Uses

Tetrakis(hydroxymethyl)phosphonium chloride solution (80% in H₂O) has been used as a reducing agent and stabilizing ligand for the synthesis of gold nanoparticles (AuNPs) from gold(III) chloride trihydrate (HAuCl₄.3H₂O). It is a tetra-functional, amine-reactive, aqueous crosslinker that can be used for tuning the properties of protein-based hydrogels for 3D cell encapsulation applications.

Definition

A crystalline compound made by the reaction of phosphine, formaldehyde, and hydrochloric acid.

General Description

Clear slightly viscous,colorless to yellow liquid (20% H2O solution).

Air & Water Reactions

Hygroscopic. Water soluble.

Reactivity Profile

Tetrakis(hydroxymethyl)phosphonium chloride reacts vigorously with oxidizers and alkalis. Reacts with cellulose.

Health Hazard

ACUTE/CHRONIC HAZARDS: Tetrakis(hydroxymethyl)phosphonium chloride may be corrosive. When heated to decomposition, it may emit very toxic fumes of POx, hydrogen chloride and bis(chloromethyl)ether. Decomposition of Tetrakis(hydroxymethyl)phosphonium chloride in an aqueous environment may produce phosphine, formaldehyde and hydrogen chloride.

Fire Hazard

Tetrakis(hydroxymethyl)phosphonium chloride is probably combustible.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise it from AcOH and dry it at 100o in a vacuum. An 80% w/v aqueous solution has d4 1.33 [Reeves J Am Chem Soc 77 3923 1955]. [Beilstein 1 IV 3062.]

Tetrakis(hydroxymethyl)phosphonium chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Tetrakis(hydroxymethyl)phosphonium chloride Suppliers

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View Lastest Price from Tetrakis(hydroxymethyl)phosphonium chloride manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Tetrakis(hydroxymethyl)phosphonium chloride 124-64-1
Price: US $1.00-4.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200000KG
Release date: 2025-05-14

Hebei Chuanghai Biotechnology Co., Ltd

Product: Tetrakis(hydroxymethyl)phosphonium chloride 124-64-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2022-09-30

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Tetrakis(hydroxymethyl)phosphonium chloride 124-64-1
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-28

124-64-1, Tetrakis(hydroxymethyl)phosphonium chloride Related Search:

Tris(hydroxymethyl)nitromethane Methyl trioctyl ammonium chloride DIMETHYLTIN DICHLORIDE Thionyl chloride Ammonium chloride Chlorodiphenylphosphine Tetrakis(hydroxymethyl)phosphonium sulfate Polyvinyl chloride DIMETHYLPHOSPHINOTHIOIC CHLORIDE Benzylmagnesium chloride Calcium chloride Tetramethylol acetylenediurea Sodium chloride Methylmagnesium chloride Tetrabutylphosphonium chloride Choline chloride Potassium chloride TETRAPHENYLOLETHANE GLYCIDYL ETHER

THPS-UPC

THPC

TETRA(HYDROXYMETHYL)PHOSPHONIUM CHLORIDE

TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM CHLORIDE

tetramethylolphosphonium chloride

nci-c55061

Phosphonium,tetrakis(hydroxymethyl)-,chloride

pyrosettkc

tetrakis-(hydroxymethyl)fosfoniumchlorid

tetrakis(hydroxymethyl)phosphochloride

tetrakis(hydroxymethyl)-phosphoniuchloride

tetrakis(hydroxymethyl)phosphonium

TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM CHLOR IDE, 80% SOLUTION IN WATER

TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM CHLOR IDE, 80% IN H2O

Tetrakis(Hydroxymethyl)Phosphorium Chloride

TetrakisHydroxymethylPhosphoniumChloride(Thpc)

AURORA KA-1157

tetrakis(hydroxymethyl)phosphonium chloride solution

HISHICOLIN THPC

Tetrakis(hydroxymethyl)phosphonium Chloride (ca. 80% in Water)

TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM CHLORIDE, CA. 80% SOLUTION IN WATER

meso-THPC

TETRAKIS(HYDROXYMETHYL)PHOSPHONIUM CHLORIDE: 80% IN WATER

Tetrakis(HydroxyMethyl) PosphoniuM Chloride

Tetrakis(hydroxyMethyl)phosphoniuM chloride solution,~80% in H2O

PhosphoniuM,tetrakis(hydroxyMethyl)-, chloride (1:1)

Tetrakis(hydroxymethyl)phosphonium chloride, 80% solution in H2O

Tetrakis(hydroxymethyl) phosphonium chloride (70-80 % in water)

SQJGLHL

Tetrakis(hydroxymethyl)phosphanium chloride

Tetrakis(hydroxymethyl)phosphonium chloride solution,~8% in H2O

Tetramethyl phosphorus chloride (THPC)

Tetrakis(hydroxymethyl)phosphanium chloride,80% in water

124-64-1

124-61-1

24-64-1

HOCH24PCl

C4H12O4PClC4H12ClO4P

CH2OH4PCl

C4H12O4PCl

C4H12ClO4P

C10H24O12P2

Phosphonium Compounds

Synthetic Reagents

Phosphonium Salts

Phase Transfer Catalysts

texitile auxiliary agents

Phosphonium Compounds

Greener Alternatives: Catalysis

Phase Transfer Catalysts

Phosphonium Salts