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Tetrakis(hydroxymethyl)phosphonium chloride

Product Name
Tetrakis(hydroxymethyl)phosphonium chloride
CAS No.
124-64-1
Chemical Name
Tetrakis(hydroxymethyl)phosphonium chloride
Synonyms
THPC;SQJGLHL;THPS-UPC;meso-THPC;pyrosettkc;nci-c55061;AURORA KA-1157;HISHICOLIN THPC;tetramethylolphosphonium chloride;tetrakis(hydroxymethyl)phosphonium
CBNumber
CB2166508
Molecular Formula
C4H12ClO4P
Formula Weight
190.56
MOL File
124-64-1.mol
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Tetrakis(hydroxymethyl)phosphonium chloride Property

Melting point:
154°C
Boiling point:
115°C/760mmHg
Density 
1.341 g/mL at 25 °C
vapor pressure 
0Pa at 25℃
refractive index 
n20/D 1.512
form 
Solution
pka
6.05[at 20 ℃]
color 
Clear light pink or yellow-green
Water Solubility 
>=10 g/100 mL at 20 ºC
BRN 
3631669
InChI
InChI=1S/C4H12O4P.ClH/c5-1-9(2-6,3-7)4-8;/h5-8H,1-4H2;1H/q+1;/p-1
InChIKey
AKXUUJCMWZFYMV-UHFFFAOYSA-M
SMILES
[P+](CO)(CO)(CO)CO.[Cl-]
LogP
-9.8
CAS DataBase Reference
124-64-1(CAS DataBase Reference)
EPA Substance Registry System
Tetrakis(hydroxymethyl)phosphonium chloride (124-64-1)
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Safety

Hazard Codes 
T,N
Risk Statements 
21-25-38-41-42/43-51/53
Safety Statements 
22-26-36/37/39-45-60-61-23
RIDADR 
UN 2810 6.1/PG 3
WGK Germany 
3
RTECS 
TA2450000
HazardClass 
8
PackingGroup 
III
HS Code 
29319019
Hazardous Substances Data
124-64-1(Hazardous Substances Data)
Toxicity
mammal (species unspecified),LD50,oral,400mg/kg (400mg/kg),Kobunshi. High Polymers. Vol. 24, Pg. 788, 1975.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
404861
Product name
Tetrakis(hydroxymethyl)phosphonium chloride solution
Purity
80% in H2O
Packaging
100ml
Price
$75.5
Updated
2024/03/01
Sigma-Aldrich
Product number
404861
Product name
Tetrakis(hydroxymethyl)phosphonium chloride solution
Purity
80% in H2O
Packaging
500ml
Price
$220
Updated
2024/03/01
TCI Chemical
Product number
T0607
Product name
Tetrakis(hydroxymethyl)phosphonium Chloride (ca. 80% in Water)
Packaging
25mL
Price
$19
Updated
2021/12/16
TCI Chemical
Product number
T0607
Product name
Tetrakis(hydroxymethyl)phosphonium Chloride (ca. 80% in Water)
Packaging
500mL
Price
$162
Updated
2021/12/16
TRC
Product number
T298578
Product name
Tetrakis(hydroxymethyl)phosphonium Chloride (ca. 80% in Water)
Packaging
1mL
Price
$45
Updated
2021/12/16
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Tetrakis(hydroxymethyl)phosphonium chloride Chemical Properties,Usage,Production

Chemical Properties

Clear light pink or yellow-green solution

Uses

Flame-retarding agent for cotton fabrics. May be used in combination with triethylolamine and urea (Roxel process) or with triethanolamine and tris(1-aziridinyl) phosphine oxide.

Uses

Tetrakis(hydroxymethyl)phosphonium chloride solution (80% in H2O) has been used as a reducing agent and stabilizing ligand for the synthesis of gold nanoparticles (AuNPs) from gold(III) chloride trihydrate (HAuCl4.3H2O). It is a tetra-functional, amine-reactive, aqueous crosslinker that can be used for tuning the properties of protein-based hydrogels for 3D cell encapsulation applications.

Definition

A crystalline compound made by the reaction of phosphine, formaldehyde, and hydrochloric acid.

General Description

Clear slightly viscous,colorless to yellow liquid (20% H2O solution).

Air & Water Reactions

Hygroscopic. Water soluble.

Reactivity Profile

Tetrakis(hydroxymethyl)phosphonium chloride reacts vigorously with oxidizers and alkalis. Reacts with cellulose.

Health Hazard

ACUTE/CHRONIC HAZARDS: Tetrakis(hydroxymethyl)phosphonium chloride may be corrosive. When heated to decomposition, it may emit very toxic fumes of POx, hydrogen chloride and bis(chloromethyl)ether. Decomposition of Tetrakis(hydroxymethyl)phosphonium chloride in an aqueous environment may produce phosphine, formaldehyde and hydrogen chloride.

Fire Hazard

Tetrakis(hydroxymethyl)phosphonium chloride is probably combustible.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise it from AcOH and dry it at 100o in a vacuum. An 80% w/v aqueous solution has d4 1.33 [Reeves J Am Chem Soc 77 3923 1955]. [Beilstein 1 IV 3062.]

Tetrakis(hydroxymethyl)phosphonium chloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Tetrakis(hydroxymethyl)phosphonium chloride Suppliers

GLR Innovations
Tel
+91 9891111994
Email
info@glrgroup.in
Country
India
ProdList
4535
Advantage
58
TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
Spectrochem Private Limited
Tel
--
Fax
--
Country
India
ProdList
1055
Advantage
58
Prasol Chemicals Private Limited
Tel
--
Fax
--
Country
India
ProdList
49
Advantage
58
CHEMSWORTH
Tel
--
Fax
--
Email
info@chemsworth.com
Country
India
ProdList
6700
Advantage
30
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View Lastest Price from Tetrakis(hydroxymethyl)phosphonium chloride manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Tetrakis(hydroxymethyl)phosphonium chloride 124-64-1
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-05-28
Hebei Yanxi Chemical Co., Ltd.
Product
Tetrakis(hydroxymethyl)phosphonium chloride 124-64-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-09-04
Hebei Weibang Biotechnology Co., Ltd
Product
Tetrakis(hydroxymethyl)phosphonium chloride 124-64-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-09-30

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