ChemicalBook > CAS DataBase List > 2-(1-Piperazinyl)pyrimidine

2-(1-Piperazinyl)pyrimidine

Product Name
2-(1-Piperazinyl)pyrimidine
CAS No.
20980-22-7
Chemical Name
2-(1-Piperazinyl)pyrimidine
Synonyms
1-(2-PYRIMIDYL)PIPERAZINE;1-pp;PMPRZ;mj13653;GOSO-003;AKOS BBS-00003690;TIMTEC-BB SBB003913;RARECHEM AH CK 0195;LABOTEST-BB LT00233196;2-PIPERAZINOPYRIMIDINE
CBNumber
CB2169600
Molecular Formula
C8H12N4
Formula Weight
164.21
MOL File
20980-22-7.mol
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2-(1-Piperazinyl)pyrimidine Property

Melting point:
32-34°C
Boiling point:
277 °C (lit.)
Density 
1.158 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.587(lit.)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Liquid After Melting
pka
8.68±0.10(Predicted)
color 
Clear yellow
Water Solubility 
almost transparency
Sensitive 
Hygroscopic
BRN 
151178
InChIKey
MRBFGEHILMYPTF-UHFFFAOYSA-N
CAS DataBase Reference
20980-22-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
RTECS 
UV9702000
TSCA 
Yes
HazardClass 
8
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2845
Product name
Buspirone Related Compound A
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
2X100MG
Price
$485
Updated
2024/03/01
Sigma-Aldrich
Product number
1078573
Product name
Buspirone Related Compound A
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
2x75mg
Price
$1300
Updated
2024/03/01
Sigma-Aldrich
Product number
421235
Product name
1-(2-Pyrimidyl)piperazine
Purity
98%
Packaging
5g
Price
$35.5
Updated
2023/06/20
TCI Chemical
Product number
P1110
Product name
1-(2-Pyrimidyl)piperazine
Purity
>98.0%(GC)
Packaging
5g
Price
$24
Updated
2024/03/01
TCI Chemical
Product number
P1110
Product name
1-(2-Pyrimidyl)piperazine
Purity
>98.0%(GC)
Packaging
25g
Price
$69
Updated
2024/03/01
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2-(1-Piperazinyl)pyrimidine Chemical Properties,Usage,Production

Chemical Properties

clear yellow liquid after melting

Uses

2-(1-Piperazinyl)pyrimidine (Buspirone EP Impurity A) is the major metabolite of Tandospirone (T006430).

Uses

The major metabolite of Tandospirone.

Definition

ChEBI: 1-(2-Pyrimidyl)piperazine is a N-arylpiperazine.

Synthesis Reference(s)

The Journal of Organic Chemistry, 18, p. 1484, 1953 DOI: 10.1021/jo50017a004

General Description

1-(2-Pyrimidyl)piperazine is a piperazine-based derivative. It is a metabolite of buspirone.

2-(1-Piperazinyl)pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

Buspirone Tandospirone Doxazosin
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2-(1-Piperazinyl)pyrimidine Suppliers

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View Lastest Price from 2-(1-Piperazinyl)pyrimidine manufacturers

Hebei Duling International Trade Co. LTD
Product
2-(1-Piperazinyl)pyrimidine 20980-22-7
Price
US $34.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000 tons
Release date
2023-01-30
Shaanxi Dideu Medichem Co. Ltd
Product
2-(1-Piperazinyl)pyrimidine 20980-22-7
Price
US $0.00-0.00/KG
Min. Order
5mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-06
Zibo Hangyu Biotechnology Development Co., Ltd
Product
2-(1-Piperazinyl)pyrimidine 20980-22-7
Price
US $60.00-600.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-07

20980-22-7, 2-(1-Piperazinyl)pyrimidineRelated Search:

2-Ethylhexyl ferulate Piperazine Piperacillin 1-Methylpiperazine N-Aminoethylpiperazine Homopiperazine 2-Chloropyrimidine Dihydrochloride BUSPIRONE (D8) 3,3-Tetramethyleneglutarimide Buspirone EP Impurity F 8-(pyrimidin-2-yl)-5,8-diazaspiro[4.5]decan-5-ium chloride Buspirone Impurity 1 (Lactone of 6-Hydroxy Buspirone) 8-(4-Chlorobutyl)-8-azaspiro[4.5]decane-7,9-dione Buspirone EP Impurity H Buspirone Impurity 2 Buspirone N-Oxide Buspirone impurity 3

  • LABOTEST-BB LT00233196
  • AKOS BBS-00003690
  • 1-PYRIMIDYL PIPERAZINE
  • 2-(1-PIPERAZINYL)PYRIMIDINE
  • 2-PIPERAZINOPYRIMIDINE
  • 2-PIPERAZIN-1-YLPYRIMIDINE
  • 1-(2-PYRIMIDINYL)PIPERAZINE
  • 1-(2-PYRIMIDYL)PIPERAZINE
  • 1-Pyrimydinyl Piperazine
  • RARECHEM AH CK 0195
  • TIMTEC-BB SBB003913
  • PMPRZ
  • 1-(Pyrimidin-2-yl)piperazine 98%
  • 1-(2-PYRIMIDINYL)PIPERZINE
  • 1-(2-PYRIMIDINYL)PIPERZINE DIHYDROCHLORIDE
  • 2-(1-Piperazinyl)pyrimidine, 98+%
  • 1-(2-PYRIMIDYL)PIPERAZINE 98%
  • 1-(2-PYRIMIDYL)PIPERAZINE DIHYDROCHLORIDE, 98+%
  • 1-(2-Pyrimidyl)piperazine dihydrochloride
  • 1-(2-Pyrimidyl)piperazine ,98%
  • 2-Piperazinylpyrimidine
  • 2-(piperazine-1-yl)-pyriMidine
  • PyriMidine, 2-(1-piperazinyl)-
  • N - (2 - pyriMidine base) piperazine
  • GOSO-003
  • Buspirone Impurity 1(Buspirone EP Impurity A)
  • Buspirone EP Impurity A
  • 2-(1-Piperazinyl)pyrimidine,99%
  • Buspirone Related Compound A
  • 1-pp
  • 2-(1-piperazinyl)-pyrimidin
  • 4-(2-pyrimidinyl)piperazine
  • mj13653
  • n-(2-pyrimidinyl)piperazine
  • 2-(1-Piperazino)pyrimidine
  • 1-(Pyrimidin-2-yl)piperazine
  • 2-(Piperazin-1-yl)pyrimidine 98%
  • 1-(2-Pyrimidinyl)piperazine 98% min
  • 2-(2-Piperazinyl)pyrimidine
  • N-(2-pyridinyl)piperazine
  • 1-(2-Pyrimidyl)piperazine&gt
  • Buspirone EP Impurity A/ Buspirone Related Compound A
  • Buspirone EP Impurity AQ: What is Buspirone EP Impurity A Q: What is the CAS Number of Buspirone EP Impurity A Q: What is the storage condition of Buspirone EP Impurity A Q: What are the applications of Buspirone EP Impurity A
  • TIANFU CHEM 2-(1-Piperazinyl)pyrimidine
  • Buspirone Related Compound A (75 mg x 2) (2-(Piperazin-1-yl)pyrimidine) (1078573)
  • Di2-(Piperazin-1-yl)pyrimidine
  • RSYY（Donepezil Hydrochloride)-16
  • Buspirone EP Impurity A Buspirone USP RC A
  • 2-Piperazinyl Pyrimidine, Hydrobromide（1：2）
  • 20980-22-7
  • C8H13N4
  • C8H12N4
  • Heterocyclic Building Blocks
  • Building Blocks
  • Piperazines
  • AMINE
  • Heterocycles, Metabolites & Impurities, Mutagenesis Research Chemicals
  • Metabolites & Impurities