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Fumonisin B2

Product Name
Fumonisin B2
CAS No.
116355-84-1
Chemical Name
Fumonisin B2
Synonyms
FB2;FUMONISIN B2;FUMONISIN B3;B2 Fumonisin B2;FUMONISIN B2, 96+%;Diquat-d4 Dibromide;fumonisin b2solution;Fumonisin B2 Standard;FUMONISIN B2 SOLUTION (50ΜFumonisin B2 in Acetonitrile
CBNumber
CB2173535
Molecular Formula
C34H59NO14
Formula Weight
705.83
MOL File
116355-84-1.mol
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Fumonisin B2 Property

Melting point:
<3200(dec)
Boiling point:
705.92°C (rough estimate)
Density 
1.2044 (rough estimate)
refractive index 
1.6630 (estimate)
Flash point:
6 °C
storage temp. 
-20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
3?+-.0.23(Predicted)
form 
Off-white solid
color 
Off-White to Beige
Stability:
Hygroscopic
CAS DataBase Reference
116355-84-1
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Safety

Hazard Codes 
T+,T,Xn,F
Risk Statements 
26/27/28-36/37/38-40-36-20/21/22-11
Safety Statements 
22-36/37/39-45-36/37-16-26
RIDADR 
UN 2811 6.1/PG 1
WGK Germany 
3
RTECS 
TZ8335000
HS Code 
29221990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F7817
Product name
Fumonisin B2 solution
Purity
1.4?mM in DMSO (0.2 μm filtered)
Packaging
500μl
Price
$421
Updated
2024/03/01
Sigma-Aldrich
Product number
344852
Product name
Fumonisin B?,
Packaging
1mg
Price
$294
Updated
2024/03/01
Sigma-Aldrich
Product number
34142
Product name
Fumonisin B2 solution
Purity
50?μg/mL in acetonitrile: water (50:50), analytical standard
Packaging
1ML
Price
$509
Updated
2024/03/01
Cayman Chemical
Product number
13227
Product name
Fumonisin B2
Purity
≥95%
Packaging
500μg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
13227
Product name
Fumonisin B2
Purity
≥95%
Packaging
1mg
Price
$230
Updated
2024/03/01
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Fumonisin B2 Chemical Properties,Usage,Production

Description

Fumonisin B2 belongs to the family of toxins known as fumonisins. It is produced by several species of Fusarium molds primarily by Fusarium verticillioide. It is one of the major mycotoxin contaminant in corn and corn-based foods. Fumonisin B2 is a structural analog of fumonisin B1 but it is more cytotoxic than the latter and it inhibits sphinganine-N-acetyltransferase (ceramide synthase).
Fumonisin B2 is a carcinogenic mycotoxin generally present on corn based food and feed-stuff, which is produced by the fungus Fusarium verticillioides and Fusarium moniliforme. Fumonisin B2 can also be detected in the industrially important fungi, Aspergillus niger.

Chemical Properties

Pale Yellow Crystalline Solid

Uses

Fumonisin B2 is a minor analogue of a family of potent mycotoxins produced by various Fusarium species, associated with animal toxicity worldwide. To date much of the research on the pharmacology of the fumonisins has focused on fumonisin B1. It is generally accepted that fumonisin B2 acts on ceramide biosynthesis, however, the pharmacology of the minor analogues is less well explored.

Uses

A mycotoxin produced by mold associated with corn. Inhibitor of sphingosine N-acyltransferase. Blocks the formation of ceramide from sphingosine.

Uses

Contact herbicide used also to produce desiccation and defoliation

Definition

ChEBI: Fumonisin B2 is a fumonisin that is (2S,3S,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,14,15-triol in which the hydroxy groups at positions 14 and 15 have each been esterified by condensation with the 1-carboxy group of 3-carboxyglutaric acid (giving a 3-carboxyglutarate ester group with R configuration in each case). It has a role as an Aspergillus metabolite and a carcinogenic agent. It is a fumonisin, a primary amino compound, a diol and a diester.

General Description

Fumonisin B2 (FB2) is a diester of tricarballylic acid and polyhydric alcohols.. Fumonisins B2 (FB2) does not have one or more hydroxyl groups at the C5 or C10 positions.

Biochem/physiol Actions

Inhibitor of sphingosine N-acyltransferase. Blocks the formation of ceramide from sphingosine.

Safety Profile

Fumonisin B2, a mycotoxin produced by Fusariummoniliforme in a variety of cereals, is a potent inhibitor of sphingosine N-acyltransferase (ceramidesynthase), blocking sphingolipid de novo synthesis. Fumonisin (FB) is a mycotoxin, a structurally similar bidentate compound composed of different polyhydric alcohols and propionic tricarboxylic acids, of which fumonisin B1 (FB1), fumonisin B2 (FB2) and fumonisin B3 (FB3) are the main components of contaminated food and its products, and a potential trigger for cancer, and has been declared by the International Agency for Research on Cancer as The International Agency for Research on Cancer has declared fumonisins as "Class 2B" toxicants (possible carcinogens to humans).

Fumonisin B2 Preparation Products And Raw materials

Raw materials

Preparation Products

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Fumonisin B2 Suppliers

Belgium 1 Canada 3 China 110 France 1 Germany 5 India 3 Norway 1 Switzerland 2 United Kingdom 7 United States 25 Global 158
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 13675144456
Fax
025-85563444
Email
sean.lv@synzest.com
Country
China
ProdList
11438
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Fax
0086-21-51320502
Email
tauto@tautobiotech.com
Country
China
ProdList
3989
Advantage
66
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
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View Lastest Price from Fumonisin B2 manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Fumonisin B2 116355-84-1
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99.0%
Supply Ability
1 ton
Release date
2020-04-23

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  • 116355-84-1
  • C34H59NO143H2O
  • C34H59NO14
  • C12H8D4Br2N2
  • C12H8D4N22Br
  • C34H59NO4
  • Sphingosine acyltransferase
  • R to Z
  • Enzyme Inhibitors
  • Enzyme Inhibitors by Enzyme
  • Enzymes, Inhibitors, and Substrates
  • Biochemicals and Reagents
  • BioChemical
  • antibiotic
  • Isotope Labelled Compounds
  • Amines
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Enzyme InhibitorsEnzyme Inhibitors by Enzyme
  • Sphingosine acyltransferase
  • Core Bioreagents
  • R to
  • Research Essentials
  • Agro-Products
  • Heterocycles
  • Isotope Labeled Compounds